Webinar - Uncovering biomarkers deep within the complex transcriptome
23/02/2016 16:00 to 23/02/2016 17:00 (Europe/Luxembourg)
Technologies such as next generation sequencing are showing us brief glimpses of the enormous complexities within our cells transcriptomes. Non-coding RNAs and alternative splicing events are new sources of biomarker development. These biomarkers help identify risk for disease, diagnose disease, guide treatment strategies, and monitor patient responses to therapy.
Robustly identifying these transcriptome changes is difficult without careful consideration of the variances and challenges inherent to each technology, thus, limiting the ability to directly compare data from different platforms, such as RNA-seq and microarrays.
Here in this talk we will explore fundamental differences between arrays and RNA-seq for discovery of biomarkers, with their advantages and disadvantages.
During the webinar, the speaker will:
- Compare the differences between arrays and RNA-seq for biomarker discovery
- Address the power and limitations of each technique
- Describe the technical variance associated with RNA-seq
- Discuss the challenges associated with whole transcriptome profiling of blood or FFPE tissue in a clinical research setting
- Answer your questions !
Considerations on the depth of sequencing required
Time : 4 pm central europe; 7 am pacific
To access the webinar :
Choose the most appropriate phone number from the list to dial in.
The phone number list will be shown on the welcome page of the webinar.
Meeting ID: 4331251
supported by :
presented by :
About the speaker
Anthony (Tony) Schweitzer is a Principal Scientist and Head of Bioinformatics for the Affymetrix Expression Business Unit.
He provides expertise globally across the organization and has responsibilities in sales, marketing, product support and R&D. He manages the EBU bioinformatics team and designs and develops next generation expression solutions. He actively participates in the US FDA SEQC/MAQCIII consortium and educates on the power and limitations of RNA-seq. He has given lectures and seminars worldwide sharing insights on transcriptomics, biomarker discovery and clinical use of microarrays for personalized medicine. He has developed a passion for aiding investigators with their research and clinical needs and empowering them with tools and insight normally beyond their capabilities.
Tony began his career in Columbus Ohio working on large scale genomic efforts including progenitor stem cell research and pathogen detection. In 1997 he relocated to the San Francisco bay area and worked on clinical target discovery programs for large pharma and biotech in the areas of Asthma and Diabetes. In 1999 Tony became the Director of Bioinformatics and IT for Metabolex Inc. and began working with Affymetrix to develop custom Affymetrix expression arrays. In 2004 he brought his bioinformatics skills and knowledge to Affymetrix laboratories heading up the ExpressionR&D informatics team and worked extensively on developing whole transcriptome expression microarrays