Regulatory B cells (Bregs) are an immunosuppressive subset of B cells that restore homeostasis following inflammatory responses, primarily via the provision of IL-10.
Bregs have been shown to be numerically and functionally decreased in autoimmunity whilst enriched in primary solid tumors. While the field of immunometabolism is rapidly expanding little is understood about Breg
metabolic requirements. Understanding the metabolic requirement of Bregs over other B cells subsets which may shed light on the dysregulation of this cell subset in disease and provide novel therapeutic targets.
I will present an historical view of Bregs function, and the signals required for their differentiation. I will also share more recent data characterising how Bregs meet their metabolic demands in response to inflammation and how
this can be manipulated for the restoration of B cell responses in patients with SLE.
House of BioHealth
Conference Room (ground floor 0)
29, rue Henri Koch
LECTURE: 11:00am – 12:15pm
Please note that registration is mandatory by sending an email to firstname.lastname@example.org or email@example.com
12:45pm – 14:00pm light lunch provided
House of BioHealth
Salle Françoise Barré Sinoussi
29 rue Henri Koch
Read more about the “Data Protection Notice: processing of personal data in the scope of events’ management”.
🇬🇧 EIT Health Digital Medical Devices – Summer School
🇬🇧 Precision Health conference: Health for all of us
Speaker : Various
🇬🇧 Joint lecture series clinical research on innovative healthcare
Speaker : Prof Martin Südmeyer, Dr Odette Fründt
🇬🇧 Probes, instruments and algorithms to propel multiscale-multimodal imaging investigations of the brain in health and disease
Lecture Series Infection & Immunity – Next-generation of multi-omics research:going to the single cell
Speaker : Prof Mark Ellisman
🇬🇧 Facilitate the development of therapies to prevent and cure Type 1 diabetes through a network of excellence
Speaker : Manuela Battaglia