Lecture Series Cancer Research - "DISSECTING ADULT AND PEDIATRIC GLIOMAS BY SINGLE-CELL GENOMICS"- Prof Mario Suva
27/05/2019 11:00 to 27/05/2019 13:00 (Europe/Luxembourg)
Prof Mario Suva is Assistant Professor of Pathology, Harvard Medical School Assistant Molecular Pathologist, Massachusetts General Hospital Institute Member, the Broad Institute of MIT and Harvard .
Human gliomas are incurable malignancies. One of the daunting challenges is repre-sented by their important level of hetero-geneity. In this lecture I will show how one can leverage cutting-edge single-cell genomic tools to interrogate human gliomas in adults and children. I will review the lessons learned in IDH-mutant oligoden-droglioma, IDH-mutant astrocytoma, H3K27M-mutant pediatric midline glioma and IDH-wildtype glioblastoma. I will show how single-cell genomics have shed light on cellular lineages of malignant cells, cancer stem cell programs, linking expression and genetics. I will also discuss lessons learned in the composi-tion of the tumor microenvironment, both myeloid cells and T cells. Finally, I will demonstrate how integrating single-cell genomics with large bulk profiles such as those from the TCGA can help shed light on brain tumor classification.
About the Lecture & Workshop series - cancer research
The LIH lecture and workshops series in Cancer Research, supported by the FNR and jointly organized with the University of Luxembourg, are gathering internationally recognised speakers to address topics around Cancer Research during 2019-2020. Please find here the current programme for 2019.
These lectures will be followed by a workshop especially dedicated to early-stage researchers.
Attendance to the lecture and workshop are free of charge. Should you be interested in registering for the workshop, please feel free to do so by sending us an email.