Dr Michel Vaillant


Dr Michel Vaillant has a background in Biology, Statistics and Epidemiology from the Universities of Montpellier and Bordeaux, France.

He has applied up-to-date statistical methods to different clinical and epidemiological studies from analysis of variance to linear mixed models or generalized mixed models in the field of neurodegenerative diseases such as Parkinson’s and Alzheimer’s.

He has developed collaborations with partners acting in Poverty Related Infectious Diseases. With a strong background in Malaria epidemiology and clinical trials, Michel has been project leader for the data management and statistics aspects of 3 large clinical trials (≈ 3400 patients) with WHO/TDR.

Michel teaches data management at the University of Metz and participates in the WHO/TDR capacity building programme, which allows African visiting scientists to be trained.

Research projects

  • MEMOLINGUA, an LIH-funded neuroimaging project with the objective to observe the functional areas of the brain that are linked to the cognitive reserve and protection against the occurrence of Cognitive Impairment. (Biostatistician) 2015-2018
  • GATIFLOXACIN: Establishment of a database for a phase 3 clinical trial of tuberculosis (gatifloxacin-containing 4-month regimen vs. standard 6-month TB regimen) in SouthAfrica, Kenya, Guinea, Senegal and Benin– 15,000 $ (validation of procedures for transfer of database) + 195,000 $, 2011-2015
  • MOXIDECTIN: Establishment of a database for a phase 3 clinical trial of onchocerciasis (moxidectin vs. standard ivermectin), Statistical Analysis and reporting in Liberia, Democratic Republic of Congo and Ghana – 128,800 $, 2012-2016
  • Project co-funded by the LIH, an anonymous donor and the National Research Fund Luxembourg (FNR) in the framework of the PROVIE program. Can non motor signs be premotor signs in Parkinson’s disease? A longitudinal multicenter case-control study. (Biostatistician) 2005-2010
  • National Research Fund Luxembourg (FNR) in the framework of the BIOSAN program. MEMOVIE, a project with the objective to examine in a prospective way, the biological factors (including genetic traits) and medical conditions associated with the occurrence and evolution of Moderate Cognitive Impairment (MCI) to Alzheimer-like Disease (AD). (Biostatistician) 2003-2012
Michel Vaillant

MS - PhD

1A-B, rue Thomas Edison
L-1445 Strassen
Tel. : +352 26 970 740

Featured Publications

Single dose moxidectin versus ivermectin for Onchocerca volvulus infection in Ghana, Liberia, and the Democratic Republic of the Congo: a randomised, controlled, double-blind phase 3 trial.

  • Competence Center for Methodology and Statistics
October 06, 2018
2018 Oct. Lancet.392(10154):1207-1216. Epub 2018 Jan 18.
  • Opoku NO
  • Bakajika DK
  • Kanza EM
  • Howard H
  • Mambandu GL
  • Nyathirombo A
  • Nigo MM
  • Kasonia K
  • Masembe SL
  • Mumbere M
  • Kataliko K
  • Larbelee JP
  • Kpawor M
  • Bolay KM
  • Bolay F
  • Asare S
  • Attah SK
  • Olipoh G
  • Vaillant M
  • Halleux CM
  • Kuesel AC
  • Sampson A.

The Luxembourg Parkinson’s Study: a Comprehensive Approach for Stratification and Early Diagnosis.

  • Competence Center for Methodology and Statistics
  • Clinical and Epidemiological Investigation Center
September 26, 2018
2018 Sep. Front Aging Neurosci.10:326. Accepted.
  • Hipp G
  • Vaillant M
  • Diederich NJ
  • Roomp K
  • Satagopam VP
  • Banda P
  • Sandt E
  • Mommaerts K
  • Mosch S
  • Longhino L
  • Schweicher A
  • Hanff A-M
  • Nicolai B
  • Kolber P
  • Reiter D
  • Pavelka L
  • Binck S
  • Pauly C
  • Geffers L
  • Betsou F
  • Gantenbein M
  • Klucken J
  • Gasser T
  • Hu M
  • Balling R
  • Krueger R.
See all publications