Research Group - Dr Yvan Devaux

Activities

Dr Yvan Devaux is head of the Cardiovascular Research Unit at LIH. 

Using a thoroughly validated experimental pipeline including both discovery and validation phases, Yvan and his group aim to identify novel biomarkers of acute cardiac conditions such as acute myocardial infarction, cardiac arrest, heart failure, aortic stenosis and stroke. His research group focuses on RNAs and particularly non-coding RNAs such as microRNAs and long non-coding RNAs.

He founded and coordinates the Cardiolinc network, a consortium of 7 private partners and more than 49 research groups worldwide investigating the role of long non-coding RNAs in cardiac disease.

Research projects

The group has several ongoing research projects, which include :

  • Identification of microRNAs predictive of outcome after cardiac arrest, acute myocardial infarction, aortic dissection and stroke
  • Development of a diagnostic microRNA-based assay to predict outcome after acute myocardial infarction

Collaborations

  • Centre Hospitalier de Luxembourg
  • Institut National de Chirurgie Cardiaque et de Cardiologie Interventionelle
  • Institute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School
  • Firalis

Funding

  • National Research Fund of Luxembourg
  • Ministry of Research of Luxembourg

yvan devaux

Ph.D.

1A-B, rue Thomas Edison
1445 Strassen
LUXEMBOURG
Tel. : +352 26 970 303

Featured Publications

Cyclin dependent kinase inhibitor 1 C is a female-specific marker of left ventricular function after acute myocardial infarction.

  • Cardiovascular Research Unit
January 01, 2019
2019 Jan. Int J Cardiol.274:319-325. Epub 2018 Jul 10.
By:
  • Lalem T
  • Zhang L
  • Scholz M
  • Burkhardt R
  • Saccheti V
  • Teren A
  • Thiery J
  • Devaux Y
  • Cardiolinc network.

Circulating levels of microRNA 423-5p are associated with 90 day mortality in cardiogenic shock.

  • Cardiovascular Research Unit
November 24, 2018
2018 Nov. ESC Heart Fail. [Epub ahead of print].
By:
  • Jantti T
  • Segersvard H
  • Tolppanen H
  • Tarvasmaki T
  • Lassus J
  • Devaux Y
  • Vausort M
  • Pulkki K
  • Sionis A
  • Bayes-Genis A
  • Tikkanen I
  • Lakkisto P
  • Harjola VP.
See all publications