NORLUX Neuro-Oncology Laboratory 

activities

We are dedicated to advancing treatment options for malignant brain tumors, with a specific focus on diffuse gliomas. With a radically translational approach to our research, we employ patient samples and innovative patient-derived preclinical model systems that faithfully reproduce the patient tumor. In our research, we investigate the cellular and molecular basis of gliomas, we explore their capacity to invade healthy brain tissue and escape therapy. Our overarching goal is to reveal novel therapeutic targets and identify reliable biomarkers of treatment responses.   

SCIENTIFIC AREAS OF INTEREST AND ACTIVITIES

• Advanced brain tumor patient avatars for preclinical investigations and treatment efficacy studies
• Personalized medicine and pharmacogenomics
• Tumor heterogeneity at cellular, multi-omics and functional levels
• Tumor plasticity and resistance mechanisms
• Tumor-microenvironment interactions and immuno-oncology

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