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NORLUX Neuro-Oncology Laboratory 

NORLUX represents a state-of-the art multidisciplinary research group with a critical mass of competitive scientists in neuro-oncology research. 

activities

We aim to improve the treatment options for malignant brain tumors, with a focus on diffuse gliomas. With a radically translational approach to research, we work with patient samples and innovative patient-derived preclinical model systems that recapitulate the patient tumor. Our research investigates the cellular and molecular basis of gliomas, their capacity to invade the normal brain and escape therapy. Special areas of interests are tumor plasticity, tumor heterogeneity, tumor metabolism, immuno-oncology and pharmacogenomics.   

projects

  • Glioma patient avatars for personalized medicine 
  • Immuno-competent tumor organoids 
  • Personalized medicine and pharmacogenomics 
  • Glioblastoma heterogeneity, plasticity and tumor-microenvironment interactions 
  • IDH mutant glioma metabolism 
  • Novel regulators of glioma invasion 
  • Epigenetics, regulatory RNAs and functional genomics 
  • Harnessing endogenous RTK inhibitors for anti-cancer treatment 
Simone P.
Niclou
Anna
Golebiewska

Projects & clinical trials

Featured team members

  • Monika
    Dieterle
    Ph.D.
    Research Engineer
  • Sabrina
    Fritah
    Ph.D.
    Scientist
  • Anna
    Golebiewska
    Ph.D.
    Group leader
  • Eliane
    Klein
    M.S.
    Research Engineer
  • Simone
    Niclou
    Ph.D.
    Director of Department of Oncology
  • Anaïs
    Oudin
    M.S.
    Research Engineer
  • Ilaria
    Salvato

Scientific publications

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