NORLUX Neuro-Oncology Laboratory
NORLUX represents a state-of-the art multidisciplinary research group with a critical mass of competitive scientists in neuro-oncology research.
activities
We aim to improve the treatment options for malignant brain tumors, with a focus on diffuse gliomas. With a radically translational approach to research, we work with patient samples and innovative patient-derived preclinical model systems that recapitulate the patient tumor. Our research investigates the cellular and molecular basis of gliomas, their capacity to invade the normal brain and escape therapy. Special areas of interests are tumor plasticity, tumor heterogeneity, tumor metabolism, immuno-oncology and pharmacogenomics.
projects
- Glioma patient avatars for personalized medicine
- Immuno-competent tumor organoids
- Personalized medicine and pharmacogenomics
- Glioblastoma heterogeneity, plasticity and tumor-microenvironment interactions
- IDH mutant glioma metabolism
- Novel regulators of glioma invasion
- Epigenetics, regulatory RNAs and functional genomics
- Harnessing endogenous RTK inhibitors for anti-cancer treatment
Projects & clinical trials
Featured team members
Within the Luxembourg Institute of Health, qualified professionals with various expertises are working together striving for excellence. Their talent, their ability to collaborate and the complementarity of their skills are some of the key elements allowing us to create societal and economical value.
Scientific publications
LIH researchers strive to generate meaningful and disease-relevant knowledge and results for patients. Their findings are regularly published in prestigious international peer-reviewed journals, thereby extending the reach and visibility of the institute’s impact.
Related News
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Masters of Disguise: New tactics in the hunt for shapeshifting cancers
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FNR Awards 2021: LIH researchers shine at centre-stage
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Towards personalised treatment of recurrent brain tumours
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New insights into Glioblastoma invasiveness
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Advancing personalised cancer treatment through patient “avatars”
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Advancing personalised cancer treatment through patient “avatars”
Forthcoming events
