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Immuno-pharmacology and interactomics

The Immuno-Pharmacology and Interactomics group focuses on the mechanisms that lead to cellular signaling disregulation and their impact in health and disease. 

Activities

Altered cellular signalling and immune dysregulation are hallmarks of most auto-immune, inflammatory and chronic viral diseases. The expression, signalling and activity of chemokines and IFN are often altered in these pathologies but the molecular mechanisms and fine regulation at play are not completely understood. Most viruses have evolved strategies to hijack, bypass or lure these signal transducers and cellular effectors to favour their replication and/or to corrupt or evade immunity. 

Our research interests revolve around two axes: 

  • Fundamental research aiming at gaining new insights into the complex structural and cellular mechanisms that lead to altered cellular signalling and cell transformation. 
  • Translational research aiming at developing novel tools and therapeutic approaches to interfere or modulate these processes and viral replication. 
Andy
Chevigne

Projects & clinical trials

Some of the group’s research projects include: 

Featured team members

  • Hugo
    Bonnemain-Pascual
  • Andy
    Chevigne
    Ph.D.
    Group leader
  • Martyna
    Szpakowska
    M.S., Ph.D.
  • Tomasz
    Uchanski
    Ph.D.
    Postdoctoral Fellow
  • May
    Wantz
    Ph.D.
    Postdoctoral Fellow

Scientific publications

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