Tumor Stroma Interactions

Activities

The Tumor Stroma Interactions research group is a dynamic and multinational team studying the mechanisms leading to leukemia progression with the goal to identify new prognostic markers and therapeutic targets. 

Some of the group’s research projects include: 

• Exosomes in B-cell malignancies – to identify potential biomarkers in exosomes derived from murine preclinical models and cells of patients affected by hematologic malignancies and to test their influence on cells from the microenvironment. 
• Tumor immunology – to identify new cellular populations which could be used as biomarkers for the response to treatment and potential new therapeutic targets. 
• New therapeutic targets in CLL – to investigate the therapeutic efficacy and mode of action of new molecules inhibiting translation machinery and prohibitins in chronic lymphocytic leukemia (CLL), both in patient cells and in a murine model. 

Group Leaders

Etienne
Moussay

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JÉRÔME
Paggetti

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