multi-omics data science (modas) research group

The Multi-omics Data Science Research Group is focused on developing advanced computational and statistical methods of biomedical data analysis and interpretation. 

activities

The Multi-omics Data Science Group mainly focuses on the data obtained in cancer biology with high-throughput molecular profiling. We focus on extracting relevant biological signals and predictive features from tumors and surrounding tissues on various modalities: DNA methylation, RNA expression, protein abundance, and tissue histopathological images. Integrating the corresponding data improves our understanding of cancers and leads to better patient stratification and treatment. A special interest of the group is in contribution to translationally-oriented research through strong collaborations at the LIH, LNS and abroad. Members of the team enable cross-disciplinary research partnerships, which benefit from their diverse expertise in biostatistics, large-scale analysis and integration of multi-omics data, machine learning and scientific programming. 

Group leaders

Projects & clinical trials

The group members led or contributed to the following research projects: 

  • “Decomposition of mixed transcriptomes for classification of heterogeneous tumour samples (DEMICS)”, Luxembourg’s National Research Fund (FNR), 2018-2020. 
  • “Glioma longitudinal analysis in Luxembourg: ex vivo and in vivo functional profiling of recurrent gliomas” (GLASS-LUX), FNR, 2021-2024. 
  • “Targeting tumor propagating cells in glioblastoma: from mechanistic insights to precision medicine” (SUNRISE), Télévie PDR, Luxembourg-Belgium, 2021-2024. 

Featured team members

Corrado
Ameli
Postdoctoral Fellow
Claudia
Cerella
Senior Scientist
Maryna
Chepeleva
PhD Student
Petr
Nazarov
Group Leader
Francesca Maria
STEFANIZZI
Postdoctoral Fellow
Danial
Tabbakh
PhD Student
Ni
Zeng
Trainee

Scientific publications

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