ALLERGY AND CLINICAL IMMUNOLOGY
The work of the Allergy and Clinical Immunology group has its focus on the common pathways leading to the activation of immune reactions and the induction of immune tolerance in various diseases, with special attention to IgE-mediated allergies.
activities
The Allergy and Clinical Immunology group aims to identify and characterise novel insect venom allergens (in collaboration with Helmholtz Center, Munich) and to perform clinical-translational studies on anaphylaxis to various allergens (in collaboration with Odense Research Centre in Anaphylaxis/ORCA, University of Southern Denmark), but also on tolerance responses developing in patients undergoing allergen-specific immunotherapy (in collaboration with Centre Hospitalier de Luxembourg/CHL, Luxembourg). New targets for immune interventions and biomarkers for precision medicine will be developed and tested in pre-clinical models.
State-of-the-art techniques such as proteomics, CyTOF or gene network analysis are at our disposal to perform the studies.
Ollert
Projects & clinical trials
- Molecular and clinical-translational studies on anaphylaxis (peanut, insect venom, wheat and fish).
- Clinical-translational studies in patient cohorts with allergen-specific immunotherapy to insect venom, peanut and grass or birch pollen.
- Assessment of novel targets for immunotherapy and experimental validation in murine models of allergy and immunotherapy.
- Identification of biomarkers predicting the risk and the outcome of allergic disease and allergen-specific immunotherapy
Featured team members
-
Murilo
Bazon Postdoctoral Fellow -
Caroline
Davril Laboratory Technician -
Agnieszka
Demczuk PhD -
Olivia
Domingues Research Engineer -
Cathy
Léonard Scientist -
Markus
Ollert Director of Department of Infection & Immunity -
Nataliia
Vdovichenko Research Engineer
Scientific publications
-
Altered infective competence of the human gut microbiome in COVID-19 – 09/03/2023
-
EAACI guidelines on environmental science in allergic diseases and asthma – Leveraging artificial intelligence and machine learning to develop a causality model in exposomics – 01/01/2023
-
Allergenic risk assessment of cowpea and its cross-reactivity with pea and peanut – 01/12/2022
-
Long COVID Classification – 30/11/2022
-
Association of miR-144 levels in the peripheral blood with COVID-19 severity and mortality – 21/11/2022
-
A comprehensive, tri-national, cross-sectional analysis of characteristics and impact of pruritus in psoriasis – 28/06/2022
-
A voice-based biomarker for monitoring symptom resolution in adults with COVID-19 – 20/10/2022
-
Allergic airway inflammation delays glioblastoma progression and reinvigorates systemic and local immunity in mice – 01/01/2022
-
Omics technologies in allergy and asthma research – 01/01/2022
-
Biotin interference can cause false-negative specific IgE results in patients with anaphylaxis – 01/01/2022
Related News
