Infection and Immunotherapy Research Group
The goal of the Infection and Immunotherapy Research (IIR) is to develop new immunotherapies against infectious diseases and cancer. They aim to provide a new translational understanding on HIV cure, bacterial infections and of cancer immunology. The group is also involved in clinical research working towards the elimination of HIV and Hepatitis in Luxembourg.
Aims and objectives
We focus on the development of immunotherapeutic complexes and NK cell engagers boosting innate immunity against viruses, bacteria and cancer cells for further elimination by the immune system. Our research encompasses protein engineering, virology, bacteriology, immunoassays and preclinical studies for the design of targeted therapeutic approaches.
HIV and viral hepatitis elimination
Our group support the monitoring of HIV and Hepatitis elimination in Luxembourg, as part of international research and surveillance networks, through outreach projects and clinical studies from the national HIV and Hepatitis programmes.
Projects & clinical trials
Featured team members
Barros PhD Student
Devaux Group Leader and Deputy Head Quality & Safety
Dokuz Visiting Researcher
Iserentant Research Engineer
Pitiot Postdoctoral Fellow
Rolin Postdoctoral Fellow
Servais Research Engineer
Scientific publications
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Global and regional molecular epidemiology of HIV-1 during 1990–2024 – 01/01/2026
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Assessment of NK cell cytotoxicity induced by IL-15 based immunotherapy against cancer cells – 17/04/2026
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Use of the Workbook Method to estimate the prevalence of chronic hepatitis B infections in the European Union and European Economic Area, 2022 – 09/04/2026
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immunoHuMiX – 24/03/2026
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Co-occurrence of memory impairment and fatigue distinguishes post COVID from pandemic-related health effects in the 4-year CON-VINCE cohort study – 27/10/2025
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Directed-complement killing of Pseudomonas aeruginosa protects against lethal pneumonia – 16/09/2025
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Directed-Complement Activation as a Novel Immunotherapeutic Approach for HER2-Breast Cancer – 05/09/2025
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Standardising monitoring data on drug-related infectious diseases among people who inject drugs in Europe – an update of the European Union Drugs Agency technical protocol, 2024 – 31/07/2025
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Fighting Antibiotic Resistance – 27/03/2025
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Exploiting complement for targeted therapies against Pseudomonas aeruginosa infection and breast cancer – 21/01/2025
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