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THE HIV-CLINICAL AND TRANSLATIONAL RESEARCH GROUP

The HIV Clinical and Translational Research (HIV-CTR) Group focuses on clinically oriented research in the field of HIV, hepatitis and SARS-COV-2 and provides new translational knowledge in immunology.  

ACTIVITIES

The HIV Clinical and Translational Research (HIV-CTR) Group emerged from the Reference Laboratory of Retrovirology offering specialised technical support for the clinical follow-up of HIV and HCV-infected patients in Luxembourg since 1990. The group joined the Department of Infection and Immunity under the direction of  Dr Carole Seguin-Devaux, and lead HIV clinical research in the field of resistance to antiviral therapy, transmission, molecular epidemiology and HIV Cure since 2014. 

The HIV-CTR research team: 

  • Provides new translational knowledge on HIV cure and in immunology. 
  • Develop immunotherapeutic complexes boosting complement or NK cells activation against viruses, bacteria or cancer cells for further elimination by the immune system. 
  • Since the beginning of the COVID-19 epidemic, the group has developed SARS-CoV-2 cultures and HIV-pseudotypes/viral neutralisation assays for SARS-CoV-2 to assess the potency of antivirals and neutralising antibodies, respectively. 

The Group is a partner in several European HIV and HCV networks, collaborates with lifescience and biotech companies, and has built up a network in Sub-Saharian African countries to support knowledge and technology transfer for the clinical management of HIV and hepatitis-infected patients.  

Collaborations: 

Carole
Seguin-Devaux

Projects & clinical trials

Featured team members

  • Gilles
    Iserentant
    M.S.
    Research Engineer
  • Danielle
    Perezbercoff
    Ph.D.
    Senior Scientist
  • Samiha
    Regaia
    M.S.
    Research Engineer
  • Carole
    Seguin
    Ph.D.
    Group leader
  • Jean-Yves
    Servais
    M.S.
    Research Engineer

Scientific publications

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