Wissenschaftliche Publikationen
Die Forschenden am LIH haben den Anspruch, bedeutsames und für Erkrankungen relevantes Wissen und entsprechende Ergebnisse für Patienten in Luxemburg und Europa hervorzubringen. Ihre Forschungsergebnisse werden regelmäßig in renommierten internationalen, von unabhängigen Gutachtern geprüften Fachzeitschriften publiziert. Dadurch vergrößern sie die Reichweite und Sichtbarkeit des Instituts und seine Bedeutung.
Wissenschaftliche Veröffentlichungen
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Personalized functional profiling using ex-vivo patient-derived spheroids points out the potential of an antiangiogenic treatment in a patient with a metastatic lung atypical carcinoid – 31/12/2022
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ORFhunteR – 01/05/2022
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Differences and Interactions in Placental Manganese and Iron Transfer across an In Vitro Model of Human Villous Trophoblasts – 18/03/2022
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Noncoding RNAs in age-related cardiovascular diseases – 16/03/2022
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Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies – 16/03/2022
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Is vitamin A an antioxidant? – 16/03/2022
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Wearable technology in orthopedic trauma surgery – An AO trauma survey and review of current and future applications – 15/03/2022
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Chimpanzee exposure to pollution revealed by human biomonitoring approaches – 15/03/2022
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The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD – 14/03/2022
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Trained through generations – 11/03/2022
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Consensus guidelines for the validation of qRT-PCR assays in clinical research by the CardioRNA consortium – 10/03/2022
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Carbonic Anhydrase IX – 09/03/2022
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A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise – 08/03/2022
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Surgical simulation training should become a mandatory part of orthopaedic education – 28/02/2022
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Comparison of Acetabular Labral Reconstruction With 7-mm Tibialis Anterior Allograft and 5-mm Iliotibial Band Autograft at Minimum 2-Year Follow-up – 28/02/2022
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Tolerable upper intake level for dietary sugars – 28/02/2022
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Safety of dried coffee husk (cascara) from Coffea arabica L. as a Novel food pursuant to Regulation (EU) 2015/2283 – 25/02/2022
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Additive Effect of Dopaminergic Medication on Gait Under Single and Dual-Tasking Is Greater Than of Deep Brain Stimulation in Advanced Parkinson Disease With Long-duration Deep Brain Stimulation – 25/02/2022
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Regulating Proteasome Activity – 23/02/2022
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Editorial – 23/02/2022
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Unspecific CTL Killing Is Enhanced by High Glucose via TNF-Related Apoptosis-Inducing Ligand – 21/02/2022
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Enzymatic activity of glycosyltransferase GLT8D1 promotes human glioblastoma cell migration – 18/02/2022
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Global change in hepatitis C virus prevalence and cascade of care between 2015 and 2020 – 15/02/2022
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PINK1 Protects against Staurosporine-Induced Apoptosis by Interacting with Beclin1 and Impairing Its Pro-Apoptotic Cleavage – 15/02/2022
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Measles – 12/02/2022
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Stress hormone signalling inhibits Th1 polarization in a CD4 T-cell-intrinsic manner via mTORC1 and the circadian gene PER1 – 10/02/2022
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Prevalence of hepatitis E virus antibodies in cattle in Burkina Faso associated with swine mixed farming – 09/02/2022
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Retrograde Procedural Memory in Parkinson’s Disease – 09/02/2022
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Editorial – 03/02/2022
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Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress – 01/02/2022
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Neurodegeneration and neuroinflammation are linked, but independent of alpha-synuclein inclusions, in a seeding/spreading mouse model of Parkinson’s disease – 29/01/2022
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Analysis of the Origin and Dissemination of HIV-1 Subtype C in Bulgaria – 27/01/2022
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COVID-19 – 27/01/2022
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Spatiotemporal and Ground-Reaction Force Characteristics as Risk Factors for Running-Related Injury – 20/01/2022
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Improving Diabetes-Related Biomedical Literature Exploration in the Clinical Decision-making Process via Interactive Classification and Topic Discovery – 18/01/2022
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Editorial – 17/01/2022
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Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection – 13/01/2022
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The role of serum 25 (OH) vitamin D level in the correlation between lipid profile, body mass index (BMI), and blood pressure – 13/01/2022
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Single-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson’s disease – 13/01/2022
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A Hot Topic – 12/01/2022
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Dairy Intake and Parkinson’s Disease – 08/01/2022
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Burden of non-communicable disease studies in Europe – 07/01/2022
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DYT6 mutated THAP1 is a cell type dependent regulator of the SP1 family – 07/01/2022
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Clinical and biological risk factors associated with inflammation in patients with type 2 diabetes mellitus – 06/01/2022
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Unexpectedly High Prevalence of Hepatitis C Virus Infection, Southern Laos – 01/01/2022
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Safety of hydrothermally treated kernels from edible Jatropha curcas L. (Chuta) as a novel food pursuant to Regulation (EU) 2015/2283 – 01/01/2022
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Guidance for establishing and applying tolerable upper intake levels for vitamins and essential minerals – 01/01/2022
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AllergoOncology – 01/01/2022
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Determinants of Self-Stigma in People with Parkinson’s Disease – 01/01/2022
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Prevalence and Cost of Care for Parkinson’s Disease in Luxembourg – 01/01/2022
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Lower impact forces but greater burden for the musculoskeletal system in running shoes with greater cushioning stiffness – 01/01/2022
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Das Knie im Spitzensport – 01/01/2022
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Allgemeinärzte raten nach einer Gesundheitskampagne nicht zu mehr körperlicher Aktivität – 01/01/2022
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A Specific CD44lo CD25lo Subpopulation of Regulatory T Cells Inhibits Anti-Leukemic Immune Response and Promotes the Progression in a Mouse Model of Chronic Lymphocytic Leukemia – 01/01/2022
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Brominated flame retardants, a cornelian dilemma – 01/01/2022
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DJ-1 depletion prevents immunoaging in T-cell compartments – 01/01/2022
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Safety of oil from Schizochytrium sp. (strain ATCC 20889) for use in infant and follow-on formula as a novel food pursuant to Regulation (EU) 2015/2283 – 01/01/2022
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Wearable gait analysis systems – 01/01/2022
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Ungewöhnliche Ursache für lumbale Beschwerden im Leistungssport – 01/01/2022
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Machine learning and conventional statistics – 01/01/2022
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Eine ausführliche Analyse des Side Hop Tests bei Patienten 9 Monate nach Rekonstruktion des vorderen Kreuzbandes – 01/01/2022
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Introgressive hybridisation between domestic pigs (Sus scrofa domesticus) and endemic Corsican wild boars (S. s. meridionalis) – 01/01/2022
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Mendelian Randomisation Study of Smoking, Alcohol, and Coffee Drinking in Relation to Parkinson’s Disease – 01/01/2022
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Gonadotropins as novel active partners in vascular diseases – 01/01/2022
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Impact of COVID-19 Pandemic on (Health) Care Situation of People with Parkinson’s Disease in Germany (Care4PD) – 31/12/2021
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Surgical resection of glioblastomas induces pleiotrophin-mediated self-renewal of glioblastoma stem cells in recurrent tumors – 29/12/2021
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Patient-oriented perspective on chemokine receptor expression and function in glioma – 28/12/2021
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Association between Dietary Factors and Constipation in Adults Living in Luxembourg and Taking Part in the ORISCAV-LUX 2 Survey – 28/12/2021
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Safety of Eurycoma longifolia (Tongkat Ali) root extract as a novel food pursuant to Regulation (EU) 2015/2283 – 22/12/2021
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The european prevalence of resistance associated substitutions among direct acting antiviral failures – 22/12/2021
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Safety of Wolffia globosa powder as a Novel food pursuant to Regulation (EU) 2015/2283 – 22/12/2021
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Safety of tetrahydrocurcuminoids from turmeric (Curcuma longa L.) as a novel food pursuant to Regulation (EU) 2015/2283 – 22/12/2021
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Cancer cell heterogeneity and plasticity – 21/12/2021
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Leveraging non-coding RNAs to fight cardiovascular disease – 21/12/2021
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Multimorbidity in large Canadian urban centres: A multilevel analysis of pooled 2015–2018 cross-sectional cycles of the Canadian Community Health Survey – 20/12/2021
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Exercise-Based Injury Prevention in High-Level and Professional Athletes – 17/12/2021
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Critical Assessment of MetaProteome Investigation (CAMPI) – 15/12/2021
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Editorial – 15/12/2021
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Examining the double burden of malnutrition for preschool children and women of reproductive age in low-income and middle-income countries – 14/12/2021
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Associations Between Device-Measured Physical Activity and Glycemic Control and Variability Indices Under Free-Living Conditions – 14/12/2021
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Safety of iron hydroxide adipate tartrate as a novel food pursuant to Regulation (EU) 2015/2283 and as a source of iron in the context of Directive 2002/46/EC – 10/12/2021
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Intraoperative discrimination of native meningioma and dura mater by Raman spectroscopy – 08/12/2021
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Dietary intake of adult residents in luxembourg taking part in two cross-sectional studies—oriscav-lux (2007–2008) and oriscav-lux 2 (2016–2017) – 07/12/2021
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Clustering of obesity-related characteristics – 01/12/2021
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Analyses of blood donor samples from eight provinces in Lao PDR suggest considerable variation concerning HBV exposure and carriage – 01/12/2021
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An age-stratified serosurvey against purified Salmonella enterica serovar Typhi antigens in the Lao People´s Democratic Republic – 01/12/2021
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Novel Advances in Allergy Diagnosis and Treatment – 01/12/2021
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Estimated visceral adiposity is associated with risk of cardiometabolic conditions in a population based study – 01/12/2021
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Only limited correlations between patient-reported outcomes and objectively monitored physical activity 10-years after THA – 01/12/2021
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Methods to Generate Innovative Research Ideas and Improve Patient and Public Involvement in Modern Epidemiological Research – 01/12/2021
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Outcome of revised metal-on-metal hip arthroplasties – 30/11/2021
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The Th17 cell – IL22 axis depends on glutathione upon intestinal inflammation – 29/11/2021
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Tert promoter mutations increase sense and antisense transcription from the tert promoter – 26/11/2021
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Randomised crossover trial comparing algorithms and averaging times for automatic oxygen control in preterm infants – 24/11/2021
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Early-life adversity leaves its imprint on the oral microbiome for more than 20 years and is associated with long-term immune changes – 24/11/2021
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The antioxidant glutathione as a regulator of natural killer cell immunity – 21/11/2021
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DNA Repair and Innate Immune Response in Glioblastoma – PROJECT REPORT, November 2021 – 19/11/2021
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Unravelling data for rapid evidence-based response to COVID-19 – 18/11/2021
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Impact of small extracellular vesicles on anti-tumor immunity in chronic lymphocytic leukemia in vivo – 17/11/2021
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Special issue “microglia heterogeneity and its relevance for translational research” – 16/11/2021
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Impact of epithelial to mesenchymal transition on the regulation of anti-tumour immune response in breast cancer – 16/11/2021
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Effect of creatine and EDTA supplemented diets on European seabass (Dicentrarchus labrax) allergenicity, fish muscle quality and omics fingerprint – 16/11/2021
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Comparison of three galenic forms of lamivudine in young West African children living with Human Immunodeficiency Virus – 16/11/2021
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Safety of water lentil powder from Lemnaceae as a Novel Food pursuant to Regulation (EU) 2015/2283 – 15/11/2021
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Personalized drug screening for functional tumor profiling – 15/11/2021
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High nevirapine levels in breast milk and consequences in HIV-infected child when initiated on antiretroviral therapy – 15/11/2021
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(Eco)toxicological tests for assessing impacts of chemical stress to aquatic ecosystems – 15/11/2021
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Extension of use of nicotinamide riboside chloride as a novel food pursuant to Regulation (EU) 2015/2283 – 12/11/2021
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Impact of chromatin dynamics and dna repair on genomic stability and treatment resistance in pediatric high‐grade gliomas – 12/11/2021
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Relevance of Frequency-Domain Analyses to Relate Shoe Cushioning, Ground Impact Forces and Running Injury Risk – 11/11/2021
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IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation – 09/11/2021
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Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function – 09/11/2021
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Food-allergic patients: from phenotype to endotype for biomarker discovery – 09/11/2021
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Biomarkers for detection of lung cancer – 04/11/2021
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Signaling, function and modulation of CXCR3 variants – 03/11/2021
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Dietary modulation alters susceptibility to listeria monocytogenes and salmonella typhimurium with or without a gut microbiota – 02/11/2021
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Mondo-A Maintains Aggressiveness in Common Acute Lymphoblastic Leukemia (B-All) by Modulating the Metabolic Stress Response and can be Targeted by a Designer Drug – 01/11/2021
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Multiomic single nucleus RNA- and ATACSEQ profiling reveals regulators of glioma cell state diversity – 01/11/2021
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Detection of COVID-19 from voice, cough and breathing patterns – 01/11/2021
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Raman spectroscopy as a diagnostic tool in neuropathology – 01/11/2021
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The role of IDH1 R132H mutation in glioma an investigation by genome-editing in human induced pluripotent stem cells – 01/11/2021
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EntropyHub – 01/11/2021
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A DNA Damage Repair Signature in Pediatric High-Grade Gliomas: XRCC1 and PARP1, Key Biomarkers – 01/11/2021
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Inhibition of GBM invasion by the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor antagonist Perampanel – 01/11/2021
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Investigating T cells in the context of Neuroimmunology: Molecular and cellular mechanisms during a stress response and a patient-based study in Parkinson’s disease – 01/11/2021
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European Health Interview Survey (EHIS): Obésité, Nutrition et Activité physique – 3 ème vague – 2019 (Fact sheet) – 01/11/2021
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Relevance of N6-methyladenosine regulators for transcriptome – 01/11/2021
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New section on carbohydrate epitopes in the WHO/IUIS allergen nomenclature website – 01/11/2021
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Vicilin IgE-cross-reactivity is responsible for in vitro allergenicity to cowpea in patients with legume allergy – 01/11/2021
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Validation of a sensor-based gait analysis system with a gold-standard motion capture system in patients with parkinson’s disease – 01/11/2021
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Raman spectroscopy as a tool in neurosurgery – 01/11/2021
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Allergy burden in luxembourg: A population-based, cross-sectional health survey paralleled by component-resolved-IgE-diagnosis – 01/11/2021
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Exploring the contribution of the mitochondrial disulfide relay system to Parkinson’s disease – 01/11/2021
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Whey-and soy protein isolates added to a carrot-tomato juice alter carotenoid bioavailability in healthy adults – 31/10/2021
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Intérêt d’une approche géostatistique pour analyser les disparités géographiques de la couverture vaccinale contre les papillomavirus humains en France – 30/10/2021
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Digital technology and disease surveillance in the COVID-19 pandemic – 29/10/2021
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An adaptive network model of the role of the gut-brain axis in parkinson’s disease – 29/10/2021
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Safety of the extension of use of galacto-oligosaccharides as a Novel food pursuant to Regulation (EU) 2015/2283 – 27/10/2021
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Transcriptional cooperation of PBX1 and PAX6 in adult neural progenitor cells – 25/10/2021
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Advanced analytical methods to assess physical activity behavior using accelerometer time series – 25/10/2021
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The Moderating Role of Resilience in the Personality-Mental Health Relationship During the COVID-19 Pandemic – 21/10/2021
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Safety of mung bean protein as a novel food pursuant to Regulation (EU) 2015/2283 – 20/10/2021
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Organic foods and contribution to the protection of body cells and molecules (lipids and DNA) from oxidative damage: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 – 20/10/2021
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The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1 – 19/10/2021
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Current landscape and future perspectives in preclinical MR and PET imaging of brain metastasis – 14/10/2021
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Peripheral blood RNA biomarkers for cardiovascular disease from bench to bedside – 14/10/2021
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Waning of maternal antibodies against measles suggests a large window of susceptibility in infants in lao people’s Democratic republic – 13/10/2021
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Parkinson’s Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2-Hydroxypropyl-β-Cyclodextrin Treatment – 12/10/2021
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In silico approach for validating and unveiling new applications for prognostic biomarkers of endometrial cancer – 09/10/2021
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Gastric lipase can significantly increase lipolysis and carotenoid bioaccessibility from plant food matrices in the harmonized INFOGEST static in vitro digestion model – 04/10/2021
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Differentiation of primary CNS lymphoma and glioblastoma using Raman spectroscopy and machine learning algorithms – 04/10/2021
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DECONbench – 02/10/2021
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Maraviroc prevents hcc development by suppressing macrophages and the liver progenitor cell response in a murine chronic liver disease model – 01/10/2021
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Management of anaphylaxis due to COVID-19 vaccines in the elderly – 01/10/2021
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Global, regional, and national burden of stroke and its risk factors, 1990-2019 – 01/10/2021
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Unraveling the concepts of distress, burnout, and depression in type 1 diabetes – 01/10/2021
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Does prevention pay off? – 01/10/2021
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Isomaltulose and normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 – 01/10/2021
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Rubella epidemiology in the Central African Republic, 2015-2016 and molecular characterization of virus strains from 2008-2016 – 01/10/2021
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Declining incidence of HIV multidrug resistance in Europe – 01/10/2021
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Non-coding RNAs and stem cells – 01/10/2021
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Systems and Longitudinal Analysis Reveals Early-Stage and Highly Coordinated Immune Responses in Mild COVID-19 Patients – 30/09/2021
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Injuries in the European Union 2009-2018 – 30/09/2021
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Synthetic retinoids as potential therapeutics in prostate cancer—An update of the last decade of research – 29/09/2021
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A new brain organoid model to study Parkinson’s Disease – 28/09/2021
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Proficiency testing program celebrates its 10th anniversary – 28/09/2021
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A dangeROS liaison: the metabolism-dependent regulation of B lymphocytes – 28/09/2021
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Population birth data and pandemic readiness in Europe – 27/09/2021
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XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase – 27/09/2021
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Integrative genomics analysis of nasal intestinal-type adenocarcinomas demonstrates the major role of CACNA1C and paves the way for a simple diagnostic tool in male woodworkers – 25/09/2021
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Computationally designed GPCR quaternary structures bias signaling pathway activation – 23/09/2021
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TGF-β promotes microtube formation in glioblastoma through thrombospondin 1 – 20/09/2021
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Deprivation of dietary fiber in specific-pathogen-free mice promotes susceptibility to the intestinal mucosal pathogen Citrobacter rodentium – 18/09/2021
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An antigen microarray protocol for COVID-19 serological analysis – 17/09/2021
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Commentary – 16/09/2021
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Multi-omics analysis to decipher the molecular link between chronic exposure to pollution and human skin dysfunction – 15/09/2021
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IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria – 13/09/2021
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Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019 – 11/09/2021
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Inhibition of GBM invasion by the A-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic acid (AMPA) Glutamate receptor antagonist Perampanel – 09/09/2021
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Tumour Immune Evasion is Promoted by Actin Cytoskeleton-Driven Polarization of Inhibitory Signals to the Immunological Synapse – 09/09/2021
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The tumor microenvironment-dependent transcription factors ahr and hif-1α are dispensable for leukemogenesis in the eµ-tcl1 mouse model of chronic lymphocytic leukemia – 08/09/2021
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“Suffocating” tumors by blocking adaptation to hypoxia – 07/09/2021
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Epigenetic regulation via PRMT7 controls monocyte migration and COPD pathogenesis – 05/09/2021
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BMI in the Associations of Plant-Based Diets with Type 2 Diabetes and Hypertension Risks in Women – 04/09/2021
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Atopic Dermatitis Patients with Pet Dander Sensitization Mount IgE and T cell Responses to Mammalian Cystatins Including the Human Self-Protein – 03/09/2021
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Deep immune profiling reveals early-stage and highly coordinated immune responses in mild COVID-19 patients – 02/09/2021
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Phenotypic heterogeneity and plasticity as resistance mechanisms in glioblastoma – 01/09/2021
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The gut commensal Bacteroides vulgatus mpk reduces Candida albicans pathogenicity towards epithelial cells – 01/09/2021
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Effectiveness of integrase strand transfer inhibitor-based regimens in HIV-infected treatment-naive individuals – 01/09/2021
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Non-invasive, neurotoxic surgery reduces seizures in a rat model of temporal lobe epilepsy – 01/09/2021
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Novel thioridazine derivates: antiproliferative and apoptosis-inducing activity on glioblastoma cells in vitro – 01/09/2021
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The circadian clock remains intact, but with dampened hormonal output in heart failure – 01/09/2021
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Metastatic potential of systemic glioblastoma stem cell lines in vivo – 01/09/2021
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Troubles musculosquelettiques au cours du diabète de type 1 – 01/09/2021
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Loss of williams syndrome transcription factor (WSTF) leads to improved temozolomide sensitivity in human glioblastoma cells irrespective of MGMT expression – 01/09/2021
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Allergic airway inflammation impacts tumor take and delays experimental glioblastoma progression – 01/09/2021
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La traduction et la synthèse des positions de consensus du CIO – 01/09/2021
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Visceral Fat Calculator – 01/09/2021
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La traduction et la synthèse des positions de consensus du CIO – 01/09/2021
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The conundrum of low covid-19 mortality burden in sub-saharan africa – 01/09/2021