PhD Student in Cancer Epitranscriptomics

Background and Research Environment

Recently established, the Cancer RNAs & Epigenetic Group (CREG) focuses on understanding the role of epigenetic and epitranscriptomic regulation in tumor progression, with the ultimate aim to develop innovative nucleic acid therapeutics against cancer. We make use of advanced molecular and cellular technologies to identify novel targets and get insight into mechanisms deregulated in cancer. We are looking for a highly motivated Ph.D. student to join our young and dynamic research group. The successful candidate will get access to several core facilities and relevant state-of-the-art technologies. S/He will benefit from an active seminar program, international conference attendances, opportunities  for professional growth. The project will be carried out in collaboration with national and international partners.

The PhD candidate will be supported through a FNRS-Televie funded project focusing on the crosstalk between m6A RNA methylation pathway and metabolic/lipid rewiring in glioma. We will leverage our expertise in genetic engineering and m6A profiling, and characterize the specific metabolome and lipidome composition of glioma.  We will assess the impact of m6A deregulation on glioma oncogenic features.

Key Skills, Experience and Qualifications

• Master’s degree in Biomedical Sciences, Biology, or Oncology
• Hands-on experience in molecular biology, cell culture (2D and 3D), immunofluorescence and microscopy
• Prior experience in RNA biology, NGS and/or Metabolism is an asset
• Understanding of common bioinformatics approaches and experience with one of the main programming languages for data analysis (R, Python) is an asset
• Curiosity, creativity, rigor, willingness to learn, team spirit and collaborative capacity, excellent time and priority management
• Fluency in English  (written and spoken) is mandatory

For any further information please contact Dr. Sabrina Fritah, Department of Cancer Research,  sabrina.fritah@lih.lu

2-year contract – renewable for an additional 2 years

Gender Equality

The LIH is an equal opportunities employer. We are fully committed to removing any discriminatory barrier related to gender, and not only, in recruitment and career progression of our staff. The LIH is attentive to gender representation among its leadership staff and aims to eliminate obstacles to the recruitment and promotion of female leaders and their career development