Transversal Translational Medicine

Featured Publications

Using high-content screening to generate single-cell gene-corrected patient-derived iPS clones reveals excess alpha-synuclein with familial Parkinson’s disease point mutation A30P.

• Transversal Translational Medicine

September 10, 2020

2020 Sep. Cells.9(9):pii: cells9092065.

By:

• Barbuti P
• Antony P
• Santos B
• Massart F
• Cruciani G
• Dording C
• Arias J
• Schwamborn J
• Kruger R.

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A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease.

• Transversal Translational Medicine

September 09, 2020

2020 Sep. Sci Transl Med.12(560).

By:

• Boussaad I
• Obermaier CD
• Hanss Z
• Bobbili DR
• Bolognin S
• Glaab E
• Wołyńska K
• Weisschuh N
• De Conti L
• May C
• Giesert F
• Grossmann D
• Lambert A
• Kirchen S
• Biryukov M
• Burbulla LF
• Massart F
• Bohler J
• Cruciani G
• Schmid B
• Kurz-Drexler A
• May P
• Duga S
• Klein C
• Schwamborn JC
• Marcus K
• Woitalla D
• Vogt Weisenhorn DM
• Wurst W
• Baralle M
• Krainc D
• Gasser T
• Wissinger B
• Krüger R.

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Excess of singleton loss-of-function variants in Parkinson's disease contributes to genetic risk.

• Transversal Translational Medicine

September 01, 2020

2020 Sep. J Med Genet.57(9):617-623. Epub 2020 Feb 13.

By:

• Bobbili DR
• Banda P
• Kruger R
• May P.

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Bidirectional relation between Parkinson's Disease and glioblastoma multiforme.

• Transversal Translational Medicine

August 20, 2020

2020 Aug. Front Neurol.11(898).

By:

• Mencke P
• Hanss Z
• Boussaad I
• Sugier P-E
• Elbaz A
• Krüger R.

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Generation of two iPS cell lines (HIHDNDi001-A and HIHDNDi001-B) from a Parkinson's disease patient carrying the heterozygous p.A30P mutation in SNCA.

• Transversal Translational Medicine

August 08, 2020

2020 Aug. Stem Cell Res.48:101951. Online ahead of print.

By:

• Barbuti PA
• Santos BFR
• Dording CM
• Cruciani G
• Massart F
• Hummel A
• Kruger R.

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