Allergies: More than a gut feeling
The prevalence of food allergies has reached epidemic levels, yet the cause remains largely unknown. In a recently published review, LIH Prof Desai discusses the clinical relevance of the gut mucosal barrier as a site for allergic sensitization to food. According to the group, studying the intricate links between the mucus barrier, the associated bacteria and the mucosal immune system may advance our understanding of the mechanisms to inform prevention and treatment strategies in food allergy.
Technology & Data Expert - BG1121
The “Human Motion, Orthopaedics, Sports Medicine, Digital Methods” (HOSD) unit is a transversal and translational research platform of the Luxembourg Institute of Health (LIH) conducting and supporting research related to movement, physical activity, physical function and mobility using laboratory-based, free-field, real-world and digital tools in orthopaedics and sports medicine as well as in other disease areas.
COVID 19 research boosted by private funding
On November 9th, the Luxembourg Institute of Health and the University of Luxembourg / LCSB, under the aegis of Research Luxembourg, welcomed the André Losch Fondation and representatives from the Luxembourg National Research Fund (FNR) to a special event dedicated to thanking both organisations for their financial support in COVID research.
Dietary fiber determines predisposition to foodborne enteric pathogens
Prof Mahesh Desai, Leader of the Eco-Immunology and Microbiome research group at DII, and his team showed that altering dietary fiber intake in mice was not only sufficient to alter susceptibility to common foodborne pathogens, Listeria monocytogenes and Salmonella Typhimurium, but also that it was able to do so regardless of the gut microbiome. Their results underscore the importance of an individual’s diet in the prevention and response to common enteric pathogens.
11 November 2021 11:00 AM
Lecture Series Cancer Research - "Identiﬁcation and characterization of cell-of-origin DNA methylation signatures in human cancers" - Prof Frank Lyko
FNR Awards 2021: LIH researchers shine at centre-stage
LIH scientists were triumphant in more than one category at the Luxembourg National Research Fund (FNR) awards 2021. In a ceremony that took place in Belval, Luxembourg Institute of Health (LIH) researchers Prof Dr Simone Niclou, Director of the Department of Oncology and group leader of the NORLUX Neuro-Oncology Laboratory and Dr Anna Golebiewska, group leader of the NORLUX Neuro-Oncology Laboratory, received the highly prestigious Outstanding Scientific Achievement award. In addition, Dr Pablo Elias Morande of the LIH Tumor Stroma Interactions group, was bestowed the Outstanding Mentor award.
LIH joins forces with Advanced BioDesign to improve cancer immunotherapy
The Tumor Immunotherapy and Microenvironment (TIME) research group of the LIH Department of Oncology (DONC) teamed-up with Advanced BioDesign to develop innovative combinatorial immunotherapy approaches. The aim is to potentiate the effectiveness of immunotherapy and provide a ground-breaking approach to treat cancers.
Hypertension: a worldwide analysis of diagnosis, treatment and control
Researchers from the LIH Department of Population Health (DoPH) – namely Dr Ala’a Alkerwi and Dr Maria Ruiz-Castell – Gwenaëlle Le Coroller from the LIH Competence Center for Methodology and Statistics (CCMS) and Prof Laetitia Huiart contributed to a collective study on hypertension with data from the national population-based studies “ORISCAV-LUX” (Observation des Risques et de la Santé Cardiovasculaire au Luxembourg) and “EHESLUX” (European Health Examination Survey in Luxembourg). This research, led by Imperial College London in the framework of the international Non-Communicable Diseases Risk Factor Collaboration (NCD-RisC), aimed to understand whether improvements in hypertension detection, treatment and control have been achieved between 1990 and 2019. Available data on this matter are often subject to methodological differences, making it difficult to compare such aspects among multiple countries. Thus, this study aimed to deliver consistent, solid and comparable data on a national, regional and global level. The results were published in August 2021 in the notorious journal The Lancet.