Researcher/Research Engineer in Bioinformatics - MO0821
LIH is looking for a highly motivated candidate with strong expertise in bioinformatics, multi-omics data analysis and data integration. The focus will be to support current research demands of all LIH departments mostly in the field of immunology and immune-related diseases. The candidate should have a strong background in the analysis and interpretation of RNA/DNA next-generation sequencing or/and methylation data. Overall, the candidate should be able to demonstrate knowledge of algorithmic and statistical concepts in Biology and Biomedicine as well as scientifically validated data analysis software.
Enabling precision cardiometabolic disease prevention through artificial intelligence
Researchers from the LIH Department of Population Health (DoPH) and from the LIH Quantitative biology Unit (QBU) leveraged advanced artificial intelligence and machine-learning approaches to classify a sample of individuals representative of the Luxembourgish population into distinct risk groups, paving the way towards more targeted strategies for the prevention of cardiometabolic diseases at a population level. The findings were published on August 6th 2021 in the Nature Portfolio journal “Scientific Reports”.
Making large-scale health data analysis a reality
The Luxembourgish National Cancer Registry (RNC) at LIH joined the consortium of the European Health Data & Evidence Network (EHDEN). The LIH team, which involves the RNC, the IT eXpertise in Health Data (IT-X-HD) and the Deep Digital Phenotyping Research Unit of the LIH Department of Population Health (DoPH), as well as the IT company Information Technology for Translational Medicine (ITTM), secured a cross-disciplinary grant for a duration of 12 months to accelerate the standardisation of clinical data.
Clinical Research Nurse in Infectious Diseases - JYF0721
The Clinical Research Nurse will : Assist the investigator and the medical team at all stages of the studies in infectious diseases (hepatitis national plan); Organise the research protocol with drug users and participate in data collection and management; Ensure the coordination of the activities on the different partners’ sites (CHL, Abrigado, Jugend- an Drogenhëllef…); Coordinate patients’ clinical monitoring in collaboration with the CHL; Carry out nursing related activities as stated in the clinical research protocol; Provide specific expertise and know-how in the follow-up of active drug users; Ensure compliance with the legal, administrative and regulatory obligations; Assist the CIEC nurse team with studies in different therapeutic areas than infectious diseases (oncology, neurology, public health, etc.), if required.
Clinical Research Nurse - JYF0521
To assist the Research Nurse Team in its day to day activities the Clinical Research Nurse will : assist the investigator and the medical team in all stages of a study; organise the research protocol and participate in data collection and management; carry out nurse-related activities as stated in the clinical research protocol; participate in communication activities for clinical research
[Press release] 2020 in review: looking back on a momentous year
“The year 2020 can undoubtedly be defined as the most momentous period in the history of science and mankind and, consequently, for LIH and for the national biomedical research ecosystem in which it operates. The present annual report provides an unparalleled opportunity to reflect on the scientific excellence of our institute and celebrate the many collective achievements of its dedicated staff” – Prof Ulf Nehrbass, LIH CEO.
From beer to bread: innovative up-cycling venture generates political interest
Claude Turmes, the Minister of Energy and Spatial Planning in Luxembourg, visited the Luxembourg Institute of Health on June 25 2021. As part of the guided tour, Dr Torsten Bohn of the Luxembourg Institute of Health (LIH) gave a short presentation on the BIOVAL project, a collaboration that aims to up-cycle the organic waste produced from the brewing of beer to create other food and chemical products.
[Press release] ‘Unlocking’ the potential of viruses to fight cancer
Researchers from the Laboratory of Oncolytic-Virus-Immuno-Therapeutics (LOVIT) at the LIH Department of Oncology (DONC) are working on the development of novel anticancer strategies based on oncolytic viruses, “good” viruses that can specifically infect, replicate in and kill cancer cells. In particular, the LOVIT team elucidated the mechanism through which the H-1PV cancer-destroying virus can attach to and enter cancer cells, thereby causing their lysis and death. At the heart of this process lie laminins, and specifically laminin γ1, a family of proteins on the surface of a cancer cell to which this virus binds, and which therefore act as the ‘door’ through which the virus enters the cells. The findings, which were published in the prestigious international journal Nature Communications, carry significant implications for the advancement of virus-based anticancer strategies and for the prediction of a patient’s response to this innovative therapeutic approach.