Internship in Leukemia Research (Master Students) - JP0621
To be part of the Tumor Stroma Interactions research group (Head: PI: Dr. E. Moussay and Dr. Jérôme Paggetti) within the Department of Oncology at the LIH, we are currently looking for a Master Student in Leukemia Research.
Quantity and quality of sleep as a potential target to prevent diabetes in the general population
A collaborative effort from the Luxembourg Institute of Health (LIH), the University of Western Ontario (Canada), Aarhus University (Denmark), the Steno Diabetes Center Aarhus (Denmark), the Centre Hospitalier de Luxembourg (CHL) and the Directorate of Health (Luxembourg), led by Dr Gloria A. Aguayo from the LIH Department of Population Health (DoPH), was the first to show a link between poor sleep quality and duration, and impaired glycaemic control. The results, published in Diabetes & Metabolism in May 2021, highlight the relevance of measuring sleep patterns as key factors in the prevention of diabetes.
Data Scientist/Bioinformatician - GF0621
LIHis looking for a highly motivated candidate in Data Science/Bioinformatics. The focus is to support research demands of all LIH departments mostly related to the need of integration of clinical, epidemiological, digital and sociodemographic data to extract useful information and knowledge for project aimed at precision public health, biomedical research and healthcare. Overall, the candidate should be able to demonstrate a broad knowledge in statistical, machine- and deep learning methods. You will be working as a part of a cross-functional team supporting LIH’s data integration, target identification and precision health activities
Postdoctoral Fellow: Gut microbiome and mucosal barrier in multiple sclerosis - MD0620
We are looking for a talented candidate to apply for a MarieSkłodowska-Curie Actions (MSCA) Individual postdoctoral fellowship 2020. The interested candidate willsubmit an MSCA fellowship jointly with the‘Ecoimmunology & Microbiome Group’ headed by Prof. Mahesh S. Desai. Theresearch project will focus on the interactions between diet, the gutmicrobiome and colonic mucus in a neurodegenerative disease multiple sclerosis(MS). The project is based on the published work (Desai et al., Cell, 2016;Martens…Desai, Nature Reviews Microbiology, 2018) on the same topic andinvolves gnotobiotic mouse models, synthetic microbial communities, MS patientcohorts and key international collaborations in Europe, USA and Japan. Thepostdoc will participate in an exciting research program in an internationalresearch team with prior success with the MSCA applications. Scientific andprofessional guidance will be provided to submit the application for apostdoctoral fellowship that, if successful, could be initiated between spring2021 to early 2022. A 'bridge funding’ option may be available to start earlierin 2020 before the outcome of the fellowship application.
[Press release] New Study Further Advances the Treatment of Chronic Pain
Building on their previous findings, scientists from the Immuno-Pharmacology and Interactomics group at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH), in collaboration with the Center for Drug Discovery at RTI International (RTI), a nonprofit research institute, have demonstrated that conolidine, a natural painkiller derived from the pinwheel flower and traditionally used in Chinese medicine, interacts with the newly identified opioid receptor ACKR3/CXCR7 that regulates opioid peptides naturally produced in the brain. The researchers also developed a synthetic analogue of conolidine, RTI-5152-12, which displays an even greater activity on the receptor. These findings, which were published on June 3rd in the prestigious international journal ‘Signal Transduction and Targeted Therapy’ (Nature publishing group), further advance the understanding of pain regulation and open alternative therapeutic avenues for the treatment of chronic pain.
LIH cancer research supported by Schëfflenger Kriibshëllef donation
On May 20th 2021, the Luxembourgish non-profit association “Schëfflenger Kriibshëllef” made a donation to the LIH Department of Oncology (DONC) to support the acquisition of new laboratory equipment for cancer research.
A year of Predi-COVID
On May 5th 2020, the first participants were being enrolled in the newly launched Predi-COVID cohort. Fast-forward to May 2021, these initial volunteers have been invited to take part in the final follow-up foreseen under the study, which will specifically seek to shed light on the features of “Long COVID” through a new dedicated questionnaire.
[Press release] Luxembourg hosts international flagship cancer epidemiology conference
From May 12th until May 14th, about 150 international scientists, clinicians, healthcare professionals and policymakers from 17 nations will gather for the 45th edition of the Group of Cancer Epidemiology and Registration in Latin Language Countries (GRELL) conference which, due to the current pandemic, will take place in a fully virtual format. Organised in Luxembourg for the first time by the National Cancer Registry of Luxembourg (Registre National du Cancer - RNC) at the Luxembourg Institute of Health (LIH), the meeting will feature several prominent speakers, providing an opportunity to discuss the latest developments in the field of cancer epidemiology with a particular focus on COVID-19 and cancer, as well as childhood and adolescent cancers. This 2021 edition of the GRELL conference is dedicated to the memory of the late Dr Michel Untereiner, oncologist and Scientific Director of the RNC between January 2013 and March 2021.
Visceral adiposity and cardiometabolic health in Luxembourg
Looking at a sample of individuals representative of the Luxembourgish population, researchers from the LIH Department of Population Health (DoPH) showed that increased visceral adipose tissue (VAT), located inside the abdominal cavity between the organs, is strongly associated with an increased risk of developing cardiometabolic disorders. To study this relationship, the scientists used recently developed and validated anthropometric predictive models of VAT, which distinguished VAT from other forms of adipose tissue. Their findings were published in the April issue of the Nature Publishing Group journal “Scientific Reports”.