The NORLUX Neuro-Oncology Laboratory is a research infrastructure that aims to develop novel therapeutic approaches against malignant brain tumours.


The research unit is organised in three subgroups focusing on glioma biology, drug resistance and systems approaches. We are working closely with the neurosurgery department of the Centre Hospitalier Luxembourg (CHL), and have established a platform for patient derived xenograft (PDX) models and for small animal in vivo imaging (MRI, PET) dedicated to brain tumour imaging.

Strategic research goals

Head of research unit

Prof Simone P. Niclou , PhD, is Head of the Norlux Neuro-Oncology Laboratory and Head of the Animal Facility at LIH. Her field of expertise includes Biology of malignant brain tumours with a focus on angiogenesis, invasion, tumour metabolism and tumour heterogeneity. She has strong expertise in patient derived animal models for gliomas.

Since 2014, she is an adjunct professor at the KG Jebsen Brain Tumour Research Center, University of Bergen, Norway.

Prof Niclou serves as a representative of Luxembourg, as Council Member of the European Association for Cancer Research (EACR) and has been appointed President of the Board of Directors of the Laboratoire National de Santé in 2015. She is a regular invited speaker at numerous international scientific conferences, and she has been a guest lecturer at national and international universities.


Simone Niclou


84, rue Val Fleuri
L-1526 Luxembourg
Tel. : +352 26970-273