Activities

The HIV Clinical and Translational Research (HIV-CTR) Group is interested in clinically oriented research in the field of resistance to antiviral therapy and transmission, as well as providing new translational knowledge on HIV cure and on HIV immunopathogenesis using humanized mouse models. The Group is a partner in several European HIV and HCV networks, collaborates with lifescience and biotech companies, and has built up a network in emerging countries (mainly in Africa) to support knowledge and technology transfer. The Group provides specialized technical support for the clinical follow-up of HIV and HCV-infected patients and is the first supplier of public health information for these infections in Luxembourg.

Collaborations:

Research projects

  • HIV Molecular Epidemiology in Europe, the SPREAD surveillance program
  • Toxicomania, hepatitis C and substitution: epidemiological, behavioral and clinical study in Luxembourg
  • Development of heteromultimeric multifunctional therapeutic molecules activating the complement action towards target cells
  • Assessment of the sequential events driving immune activation in the gut during acute HIV infection by using an in vivo model of humanized mice
  • Challenging organic syntheses inspired by nature - from natural products chemistry to drug discovery

Featured Publications

Virological response and resistances over 12 months among HIV-infected children less than two years receiving first-line lopinavir/ritonavir-based antiretroviral therapy in Cote d’Ivoire and Burkina Faso: the MONOD ANRS 12206 cohort.

  • HIV Clinical and Translational Research
April 25, 2017
2017 Apr. J Int AIDS Soc.20:21362.
By:
  • Amani-Bosse C
  • Dahourou DL
  • Malateste K
  • Amorissani-Folquet M
  • Coulibaly M
  • Dattez S
  • Emieme A
  • Barry M
  • Rouzioux C
  • N’Gbeche S
  • Yonaba C
  • Timité-Konan M
  • Mea V
  • Ouédraogo S
  • Blanche S
  • Meda N
  • Seguin-Devaux C
  • Leroy V.

Efavirenz-based simplification after successful early lopinavir-boosted-ritonavir-based therapy in HIV-infected children in Burkina Faso and Cote d'Ivoire: the MONOD ANRS 12206 non-inferiority randomised trial.

  • HIV Clinical and Translational Research
April 24, 2017
2017 Apr. BMC Med.15(1):85.
By:
  • Dahourou DL
  • Amorissani-Folquet M
  • Malateste K
  • Amani-Bosse C
  • Coulibaly M
  • Seguin-Devaux C
  • Toni T
  • Ouedraogo R
  • Blanche S
  • Yonaba C
  • Eboua F
  • Lepage P
  • Avit D
  • Ouedraogo S
  • Van de Perre P
  • N'Gbeche S
  • Kalmogho A
  • Salamon R
  • Meda N
  • Timite-Konan M
  • Leroy V
  • MONOD Study Group.
See all publications

Contact

Carole Devaux

Ph.D.

29, rue Henri Koch
L-4354 Esch-sur-Alzette
Luxembourg
Tel. : +352 26970-224