Activities

The identification, isolation and characterization of allergens is crucial for diagnosis and therapy of allergic disorders. The team focuses on the analysis of respiratory and food allergens from animal origin. A large panel of characterized fish and furry pet allergens became available during the past decade.

The use of single allergens in IgE-diagnosis allows to discriminate between a primary sensitization and cross-reactivity, a first step into personalized diagnosis and treatment. We are closely linked to the clinic through our partner, the National Service of Immuno-Allergology at CHL. The analysis of common allergen features helps to understand the allergic immune response and as a perspective, to develop strategies for patient immunotherapy.

Research projects

  • Analysis of respiratory allergens from small furry animals
  • Analysis of food allergens from fish and meat
  • Developing strategies for improved patient diagnosis, care and treatment

Featured Publications

Effect of EDTA enriched diets on farmed fish allergenicity and muscle quality; a proteomics approach.

  • Molecular and Translational Allergology
February 01, 2020
2020 Feb. Food Chem.305:125508. Epub 2019 Sep 11.
By:
  • De Magalhaes CR
  • Schrama D
  • Fonseca F
  • Kuehn A
  • Morisset M
  • Ferreira SR
  • Goncalves A
  • Rodrigues PM.

Homologous tropomyosins from vertebrate and invertebrate: Recombinant calibrator proteins in functional biological assays for tropomyosin allergenicity assessment of novel animal foods.

  • Molecular and Translational Allergology
  • Allergy and Clinical Immunology
January 01, 2020
2020 Jan. Clin Exp Allergy.50(1):105-106. Epub 2019 Oct 11.
By:
  • Klueber J
  • Costa J
  • Randow S
  • Codreanu-Morel F
  • Verhoeckx K
  • Bindslev-Jensen C
  • Ollert M
  • Hoffmann-Sommergruber K
  • Morisset M
  • Holzhauser T
  • Kuehn A.
See all publications

Contacts

Christiane Hilger

Ph.D.

29, rue Henri Koch
L-4354 Esch-sur-Alzette
Luxembourg
Tel. : +352 26970-258

Annette KUEHN

PhD

29, rue Henri Koch
L-4354 Esch-Sur-Alzette
LUXEMBOURG
Tel. : +352 26 970 335