The identification, isolation and characterization of allergens is crucial for diagnosis and therapy of allergic disorders. The team focuses on the analysis of respiratory and food allergens from animal origin. A large panel of characterized fish and furry pet allergens became available during the past decade.

The use of single allergens in IgE-diagnosis allows to discriminate between a primary sensitization and cross-reactivity, a first step into personalized diagnosis and treatment. We are closely linked to the clinic through our partner, the National Service of Immuno-Allergology at CHL. The analysis of common allergen features helps to understand the allergic immune response and as a perspective, to develop strategies for patient immunotherapy.

Research projects

  • Analysis of respiratory allergens from small furry animals
  • Analysis of food allergens from fish and meat
  • Developing strategies for improved patient diagnosis, care and treatment

Featured Publications

Effect of EDTA enriched diets on farmed fish allergenicity and muscle quality; a proteomics approach.

  • Molecular and Translational Allergology
February 01, 2020
2020 Feb. Food Chem.305:125508. Epub 2019 Sep 11.
  • De Magalhaes CR
  • Schrama D
  • Fonseca F
  • Kuehn A
  • Morisset M
  • Ferreira SR
  • Goncalves A
  • Rodrigues PM.

Homologous tropomyosins from vertebrate and invertebrate: Recombinant calibrator proteins in functional biological assays for tropomyosin allergenicity assessment of novel animal foods.

  • Molecular and Translational Allergology
  • Allergy and Clinical Immunology
January 01, 2020
2020 Jan. Clin Exp Allergy.50(1):105-106. Epub 2019 Oct 11.
  • Klueber J
  • Costa J
  • Randow S
  • Codreanu-Morel F
  • Verhoeckx K
  • Bindslev-Jensen C
  • Ollert M
  • Hoffmann-Sommergruber K
  • Morisset M
  • Holzhauser T
  • Kuehn A.
See all publications


Christiane Hilger


29, rue Henri Koch
L-4354 Esch-sur-Alzette
Tel. : +352 26970-258

Annette KUEHN


29, rue Henri Koch
L-4354 Esch-Sur-Alzette
Tel. : +352 26 970 335