Postdoctoral fellow in Cardiovascular Research and COVID-19 - YD0820
1A-B, rue Thomas Edison, Strassen 1445, Luxembourg
The host lab
The Cardiovascular Research Unit of the Department of Population Health of LIH is a translational biomedical research group headed by Dr Yvan Devaux and conducting research on all aspects of transcriptomics in cardiovascular and neurological diseases (https://cvru.lih.lu/ ). The group aims to apply its expertise on RNA biomarkers to fight against COVID-19.
Coronavirus disease 2019 (COVID-19) caused by infection with SARS coronavirus 2 (SARS-CoV-2) has reached pandemic proportions. Death rates are accentuated by cardiovascular comorbidities and arrhythmias leading to unexpected major cardiovascular events. Being able to identify COVID-19 patients at risk of developing cardiovascular events leading to death would allow improving surveillance and care. The COVIRNA project is a patient-centered Innovation Action aiming to deploy a prognostic system based on cardiovascular biomarkers of COVID-19 clinical outcomes combined with digital tools and artificial intelligence analytics. Complementary expertise of 15 EU partners from the healthcare sector, academia, association and industry will allow conducting a large retrospective study on existing cohorts of COVID-19 patients. The project aims to quickly deliver a minimally-invasive, simple, robust and affordable prognosis tool that can be used in the context of the current COVID-19 crisis as well as in further major health issues. By tackling the cardiovascular complications in COVID-19, known to contribute significantly to mortality, the project outputs are expected to have a major impact on the pandemic outcomes.
The successful candidate will be embedded in a state-of-the-art laboratory at the Department of Population Health composed of more than 90 staff members. The Cardiovascular Research Unit currently consists of two research engineers, one technician, one administrative assistant, one project manager, two PhD students and one postdoctoral fellow.
- Actively participate in all work packages of the project.
- Assist the project coordinator in supervising the implementation of the work packages and monitoring the work plan; provide support in planning, producing and reviewing the deliverables and outcomes to ensure timely delivery.
- Communicate with group members and organize the work of technicians.
- Carry out a research project independently (drafting, validation, etc.) and set up follow up projects.
- Participate in the execution of a research project (implementation, follow-up, planning) within a research team while trying to optimize productivity.
- Participate in the activities of the research unit and integrate into teams.
- Perform and analyse wet lab experiments.
- Draft reports and scientific publications, write scientific articles for peer-reviewed international journals.
- Develop scientific methodology and techniques adapted to the research project.
- Evaluate research results for patent filing together with the Compliance office and the Director of the Department.
- Establish an internal and external cooperation for the implementation of new laboratory techniques.
- Present the work as well as results during research unit meetings and at international meetings, congresses.
- Establish and disseminate the bibliography to the other researchers, students and technicians.
- Communicate problems and suggestions for possible solutions in a clear way.
- Train and supervise technicians, master students and PhD students (if applicable).
- Stay updated with the current scientific literature concerning the study.
- Participate in the societal dimension: dissemination of simplified research results to the general public (through articles, conferences, etc.).
KEY SKILLS, EXPERIENCE AND QUALIFICATIONS
- PhD or previous post-doctoral position in the area of biology, molecular biology, health, or biotechnology.
- Hands-on experience in wet lab work including the use of RNA and mammalian cell models.
- Experience in PCR, RNA work, manipulation of human samples, BSL-2 work.
- Experience in the fields of cardiology and/or immunology.
- Experience in data management is an added value.
- Knowledge of biostatistics, prediction models, artificial intelligence methods, R language is welcome.
- Knowledge of bioinformatics.
- Open minded, self-driven and curious person, willing to work in a competitive, interdisciplinary and international environment.
- Ability to work in a group as well as autonomously.
- Fluency in English with advanced writing skills for scientific publications and grant applications; another European language is welcome.
The position will be accompanied by training and mentoring opportunities to get prepared for the next career step in becoming an independent researcher.