Internship position (Master2 student) in Biomonitoring - BA0718

1A-B, rue Thomas Edison, Strassen 1445, Luxembourg
29/08/2018 10:40:05

NoSTra-ED - Novel Strategies for assessing exposure to short-lived endocrine disruptors.

Biological fluids (blood and urine), which are considered the matrices of choice for the assessment of human exposure to pollutants, are of limited use for short-life endocrine disruptors (e.g. bisphenol A, phthalates…). The main limit is related to the strong short-term variability of the concentration of these molecules in these matrices. On the contrary, hair analysis provides information that integrates exposure over longer period and therefore represents a particularly interesting alternative. The objective of the NoStra-ED project is to determine the variability of the urinary concentration of short-life endocrine disruptors and to compare the information obtained from two matrices (urine and hair) for the biomonitoring of human exposure to these pollutants within a follow-up on human volunteers and animal experimentation. As part of this Master II internship, the candidate will be trained in various state-of-the-art analytical techniques such as liquid and gas chromatography coupled with tandem mass spectrometric detection (LC-MS / MS and GC-MS / MS) as well as pre-analytical work (extraction from biological matrices, purification and concentration of extracts) with the support of highly skilled engineers. The candidate may also participate in the analysis and processing of the data produced: results formatting and interpretation, and statistical analysis under the supervision of a statistician specialized in the field of biomonitoring

What we offer and conditions

·         Students will have the opportunity to work in an interactive and international scientific environment, attend conferences by eminent scientists from abroad, and present their own work during lab meetings.

·         They will receive training in high level analytical technique (LC-MS/MS and GC-MS/MS) and analytical softwares, data interpretation and statistical analysis.

·         Applicants must be affiliated to their own University. English and/or French is mandatory.

·         Master students will receive 500€/month unless they have their own funding source, e.g. Erasmus grant


 Available for 6 months, early 2019 (Can be adjusted according to the specific requirements of the University)


Scientific contact

Dr. Brice Appenzeller, PhD

Head of the Human Biomonitoring Research Unit

Luxembourg Institute of Health, 1 rue Thomas Edison

L-1445 STRASSEN, Luxembourg

Tel: 00352 26 970 421