Lecture Series Translational Bioinformatics & Systems Biomedicine - "TRANSLATING SYSTEMS BIOLOGY-BASED SIGNATURES AS PROGNOSTIC CANCER BIOMARKERS AND STRATIFICATION TOOLS" - Prof Jochen Prehn

27/09/2018 16:00 to 27/09/2018 18:30 (Europe/Luxembourg)

Speaker

Prof Jochen Prehn is Professor of Physiology & Director, Centre for Systems Medicine, Royal College of Surgeons in Ireland.

 

Abstract

Professor Prehn is considered an international authority on the single-cell analysis and the molecular control of apoptosis, cancer cell death, nerve cell death, as well as mitochondrial function and dysfunction. This research included the development of computational approaches to understand bio- energetics, apoptosis sensitivity and apoptosis resistance at a systems level. In collaboration with clinicians (pathology, medicine, and surgery), Prof Prehn translated these approaches into clinically relevant settings, and has initiated multiple large scale, multi-partner clinical projects such as the APO-COLON and APO-DECIDE clinical studies. In his presentation, Prof Prehn will highlight his recent research applying quantitative and systems-based analyses of BCL-2 signalling, caspase signalling and cellular bioenergetics pathways. These processes represent key downstream targets of oncogenic transformation. He will in particular showcase the application of dynamic systems modelling for the identification of novel prognostic biomarkers and stratification tools for the treatment of colorectal cancer (CRC) and other solid tumours.


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schedule

16.00 - 17.00: LECTURE

University of Luxembourg

Maison des Sciences Humaines

11, Porte des Sciences 

L-4366 Esch/Alzette

Blackbox room

17.00 - 18.30: 'meet THE SPEAKER'

University of Luxembourg

Maison des Sciences Humaines

11, Porte des Sciences

L-4366 Esch/Alzette

Room N°0.207


Registration required for the 'Meet the Speaker' - send us an email

programme 2017-2018

About the Lecture & Workshop series - TRANSLATIONAL BIOINFORMATICS AND SYSTEMS BIOMEDICINE

The LIH lecture and workshops series in Translational Bioinformatics and Systems Biomedicine, supported by the FNR and jointly organized with the University of Luxembourg, are gathering internationally recognised speakers to address topics around Translational Bioinformatics and Systems Biomedicine.  Please find here  the full programme for 2017-2018.

This lecture will be followed by a workshop especially dedicated to early-stage researchers.

Attendance to the lecture and workshop are free of charge. Should you be interested in registering for the workshop, please feel free to do so by sending us an email.

When

From 27/09/2018 16:00
To 27/09/2018 18:30

Contact

Luxembourg Institute of Health
odoo@lih.lu