Lecture Series Cancer Research - "NOVEL THERAPEUTIC OPTIONS IN ADVANCED MALIGNANT MELANOMA" - Prof Jochen Utikal
22/01/2019 11:00 to 22/01/2019 12:00 (Europe/Luxembourg)
Prof Jochen Utikal is Head of the Skin Cancer Unit of the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim, Attending (Leitender Oberarzt), Department of Dermatology, Venereology
and Allergology, University Medical Center Mannheim, Ruprecht-Karl
University of Heidelberg, Germany.
Melanoma is one of the most aggressive skin cancers and originates from the oncogenic transformation of melanocytes. Its incidence has been continuously increasing in the last decade and it is often inclined to metastasize, leading to about 75% of skin cancer-related deaths. For more than 40 years, few treatment options were available for melanoma and these therapies did not increase the overall survival of patients with advanced melanoma. All clinical trials during that time were unsuccessful. Over the past 10 years, increased biological understanding and access to innovative therapeutic substances have transformed advanced melanoma into a new oncological model for treating other solid cancer types. Treatments that target BRAF mutations using selected BRAF inhibitors combined with MEK inhibitors have significantly improved response and overall survival.. Furthermore melanoma has developed into a prototype for testing checkpoint- modulating agents such as anti- CTLA4 or PD1/PDL1-inhibitors, which has increased hope for long-term survival of patients with advanced melanoma.
11.00 - 12.00: LECTURE
University of Luxembourg
Maison du Savoir
About the Lecture & Workshop series - cancer research
The LIH lecture and workshops series in Cancer Research, supported by the FNR and jointly organized with the University of Luxembourg, are gathering internationally recognised speakers to address topics around Cancer Research.
This lecture will be followed by a workshop especially dedicated to early-stage researchers.
Attendance to the lecture and workshop are free of charge. Should you be interested in registering for the workshop, please feel free to do so by sending us an email.