Latest publications

Expanding the interactome of TES by exploiting TES modules with different subcellular localizations.

  • Tumor Stroma Interactions
May 05, 2017
2017 May. J Proteome Res.16(5):2054-2071. Epub 2017 Apr 20.
By:
  • Sala S
  • Van Troys M
  • Medves S
  • Catillon M
  • Timmerman E
  • Staes A
  • Schaffner-Reckinger E
  • Gevaert K
  • Ampe C.
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Hijacker of the antitumor immune response: autophagy is showing its worst facet.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
November 18, 2016
2016 Nov. Front Oncol.6(246):246.
By:
  • Viry E
  • Noman MZ
  • Arakelian T
  • Lequeux A
  • Chouaib S
  • Berchem G
  • Moussay E
  • Paggetti J
  • Janji B.
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A high rate of telomeric sister chromatid exchange occurs in chronic lymphocytic leukaemia B-cells.

  • Tumor Stroma Interactions
  • Integrated BioBank of Luxembourg
  • Laboratory of Oncolytic-Virus-Immuno-Therapeutics
July 01, 2016
2016 Jul. Br J Haematol.174(1):57-70. Epub 2016 Mar 11.
By:
  • Medves S
  • Auchter M
  • Chambeau L
  • Gazzo S
  • Poncet D
  • Grangier B
  • Verney A
  • Moussay E
  • Ammerlaan W
  • Brisou G
  • Morjani H
  • Geli V
  • Palissot V
  • Berchem G
  • Salles G
  • Wenner T.
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The multifaceted role of autophagy in tumor evasion from immune surveillance.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
April 05, 2016
2016 Apr. Oncotarget.7(14):17591-607.
By:
  • Janji B
  • Viry E
  • Moussay E
  • Paggetti J
  • Arakelian T
  • Mgrditchian T
  • Messai Y
  • Noman MZ
  • Van Moer K
  • Hasmim M
  • Mami-Chouaib F
  • Berchem G
  • Chouaib S.
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Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-beta and miR23a transfer.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
April 01, 2016
2016 Apr. OncoImmunology.5(4):e1062968. Epub 2015 Jun 24.
By:
  • Berchem G
  • Noman MZ
  • Bosseler M
  • Paggetti J
  • Baconnais S
  • Le Cam E
  • Nanbakhsh A
  • Moussay E
  • Mami-Chouaib F
  • Janji B
  • Chouaib S.
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Autophagy Activation in the Tumor Microenvironment: A Major Process in Shaping the Antitumor Immune Response. In Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. 1st ed. (Book Chapter)

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
February 25, 2016
2016 Feb. San Diego: Academic Press, 2016. p.267-290. (Vol. 8). ISBN 978-0-12-802937-4.
By:
  • Janji B
  • Viry E
  • Mgrditchian T
  • Arakelian T
  • Medves S
  • Berchem G.
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BCR engagement in CLL: when translation goes wrong.

  • Tumor Stroma Interactions
January 28, 2016
2016 Jan. Blood.127(4):378-80.
By:
  • Paggetti J
  • Moussay E.
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Autophagy regulation of the tumor immunity: An old housekeeper for a new function. In Cell Death - Autophagy, Necrosis and Apoptosis. (Book Chapter)

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
December 16, 2015
2015 Dec. Ntuli DT, ed. Rijeka: InTech, 2015. p.37-61. ISBN 978-953-51-2236-4.
By:
  • Arakelian T
  • Mgrditchian T
  • Viry E
  • Van Moer K
  • Berchem G
  • Chouaib S
  • Janji B.
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Delineating the Tes interaction site in zyxin and studying cellular effects of its disruption.

  • Tumor Stroma Interactions
October 28, 2015
2015 Oct. PLoS One.10(10):e0140511.
By:
  • Hadzic E
  • Catillon M
  • Halavatyi A
  • Medves S
  • Van Troys M
  • Moes M
  • Baird MA
  • Davidson MW
  • Schaffner-Reckinger E
  • Ampe C
  • Friederich E.
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Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts.

  • Tumor Stroma Interactions
  • Tumor Immunotherapy and Microenvironment
  • Integrated BioBank of Luxembourg
  • Proteomics of Cellular Signaling
August 27, 2015
2015 Aug. Blood.126(9):1106-17. Epub 2015 Jun 22.
By:
  • Paggetti J
  • Haderk F
  • Seiffert M
  • Janji B
  • Distler U
  • Ammerlaan W
  • Kim YJ
  • Adam J
  • Lichter P
  • Solary E
  • Berchem G
  • Moussay E.
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Verification of the biomarker candidates for non-small-cell lung cancer using a targeted proteomics approach.

  • Proteomics of Cellular Signaling
  • Tumor Stroma Interactions
March 06, 2015
2015 Mar. J Proteome Res.14(3):1412-9. Epub 2015 Feb 9.
By:
  • Kim YJ
  • Sertamo K
  • Pierrard MA
  • Mesmin C
  • Kim SY
  • Schlesser M
  • Berchem G
  • Domon B.
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Hypoxia: A key feature of the tumor microenvironment triggers several mechanisms of evasion from natural killer and cytotoxic T lymphocytes surveillance.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
  • Cytoskeleton and Cancer Progression
November 20, 2014
2014 Nov. J Imm Res.1(2):7.
By:
  • Mgrditchian T
  • Arakelian T
  • Paggetti J
  • Viry E
  • Al-Absi A
  • Medves S
  • Moussay E
  • Berchem G
  • Thomas C
  • Janji B.
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Autophagy: An adaptive metabolic response to stress shaping the antitumor immunity.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
November 01, 2014
2014 Nov. Biochem Pharmacol.92(1):31-42. Epub 2014 Jul 17.
By:
  • Viry E
  • Paggetti J
  • Baginska J
  • Mgrditchian T
  • Berchem G
  • Moussay E
  • Janji B.
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Hypoxia-induced autophagy in tumor cells: a key target for improving cancer immunotherapy.

  • Tumor Stroma Interactions
  • Tumor Immunotherapy and Microenvironment
September 14, 2014
2014 Sep. Cancer Cell Microenviron.1(4):e213.
By:
  • Paggetti J
  • Viry E
  • Berchem G
  • Moussay E
  • Janji B.
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Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia.

  • Tumor Stroma Interactions
  • Platform National Cytometry
  • NORLUX Neuro-Oncology Laboratory
August 01, 2014
2014 Aug. Leukemia.28(8):1636-46. Epub 2014 Jan 14.
By:
  • El-Khoury V
  • Pierson S
  • Szwarcbart E
  • Brons NH
  • Roland O
  • Cherrier-De Wilde S
  • Plawny L
  • Van Dyck E
  • Berchem G.
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Autophagic degradation of GZMB/granzyme B: a new mechanism of hypoxic tumor cell escape from natural killer cell-mediated lysis.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
January 01, 2014
2014 Jan. Autophagy.10(1):173-5. Epub 2013 Nov 15.
By:
  • Viry E
  • Baginska J
  • Berchem G
  • Noman MZ
  • Medves S
  • Chouaib S
  • Janji B.
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Symplekin, a polyadenylation factor, prevents MOZ and MLL activity on HOXA9 in hematopoietic cells.

  • Tumor Stroma Interactions
December 01, 2013
2013 Dec. Biochim Biophys Acta-Mol Cell Res.1833(12):3054-3063. Epub 2013 Aug 27.
By:
  • Largeot A
  • Paggetti J
  • Broseus J
  • Aucagne R
  • Lagrange B
  • Martin RZ
  • Berthelet J
  • Quere R
  • Lucchi G
  • Ducoroy P
  • Bastie JN
  • Delva L.
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The critical role of the tumor microenvironment in shaping natural killer cell-mediated anti-tumor immunity.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
December 01, 2013
2013 Dec. Front Immunol.4:490.
By:
  • Baginska J
  • Viry E
  • Paggetti J
  • Medves S
  • Berchem G
  • Moussay E
  • Janji B.
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Stromal cell-induced miRNA alteration in chronic lymphocytic leukemia: how a minute and unavoidable cell contamination impairs miRNA profiling.

  • Tumor Stroma Interactions
August 01, 2013
2013 Aug. Leukemia.27(8):1773-6. Epub 2013 Feb 14.
By:
  • Paggetti J
  • Berchem G
  • Moussay E.
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Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
September 15, 2011
2011 Sep. Cancer Res.71(18):5976-86. Epub 2011 Aug 2.
By:
  • Noman MZ
  • Janji B
  • Kaminska B
  • Van Moer K
  • Pierson S
  • Przanowski P
  • Buart S
  • Berchem G
  • Romero P
  • Mami-Chouaib F
  • Chouaib S.
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