Latest publications
EMT impairs breast carcinoma cell susceptibility to CTL-mediated lysis through autophagy induction.
- Tumor Immunotherapy and Microenvironment
2013 Jul. Autophagy.9(7):1104-6. Epub 2013 Apr 23.
Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell-mediated lysis.
- Tumor Immunotherapy and Microenvironment
2013 Apr. Cancer Res.73(8):2418-27. Epub 2013 Feb 22.
Cooperative effects of Janus and Aurora kinase inhibition by CEP701 in cells expressing Jak2V617F.
- Tumor Immunotherapy and Microenvironment
2013 Feb. J Cell Mol Med.17(2):265-76. Epub 2013 Jan 10.
Hypoxia-inducible miR-210 regulates the susceptibility of tumor cells to lysis by cytotoxic T cells.
- Tumor Immunotherapy and Microenvironment
2012 Sep. Cancer Res.72(18):4629-41. Epub 2012 Sep 7.
Hypoxia-induced autophagy: a new player in cancer immunotherapy?
- Tumor Immunotherapy and Microenvironment
2012 Apr. Autophagy.8(4):704-6. Epub 2012 Apr 1.
Guidelines for the use and interpretation of assays for monitoring autophagy.
- Tumor Immunotherapy and Microenvironment
2012 Apr. Autophagy.8(4):445-544.
Role of the actin cytoskeleton in tumor escape to immune system and acquisition of tumor resistance to cytotoxic treatment. In Actin: Structure, functions and disease. (Book Chapter)
- Tumor Immunotherapy and Microenvironment
2012 Jan. Consuelas VA and Minas DJ, eds. Hauppauge, New York: Nova Science Publishers, 2012. p.245-255. (Protein Biochemistry, Synthesis, Structure and Cellular Functions). ISBN 978-1-62100-191-1.
Lung cancer statistics in Luxembourg from 1981 to 2008.
- Tumor Immunotherapy and Microenvironment
- Proteomics of Cellular Signaling
2011 Dec. Bull Soc Sci Med Grand Duche Luxemb.(2):43-55.
Microenvironmental hypoxia orchestrating the cell stroma cross talk, tumor progression and antitumor response.
- Tumor Immunotherapy and Microenvironment
2011 Dec. Crit Rev Immunol.31(5):357-77.
The human epidermal growth factor receptor (EGFR) gene in European patients with advanced colorectal cancer harbors infrequent mutations in its tyrosine kinase domain.
- Tumor Immunotherapy and Microenvironment
2011 Oct. BMC Med Genet.12:144.
Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression.
- Tumor Immunotherapy and Microenvironment
- Tumor Stroma Interactions
2011 Sep. Cancer Res.71(18):5976-86. Epub 2011 Aug 2.
The acquisition of resistance to TNFalpha in breast cancer cells is associated with constitutive activation of autophagy as revealed by a transcriptome analysis using a custom microarray.
- Tumor Stroma Interactions
- Tumor Immunotherapy and Microenvironment
- Platform LUXGEN - Micro-Array
2011 Jul. Autophagy.7(7):760-70. Epub 2011 Jul 1.
MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia.
- Tumor Stroma Interactions
- Tumor Immunotherapy and Microenvironment
- Platform LUXGEN - Micro-Array
2011 Apr. Proc Natl Acad Sci U S A.108(16):6573-8. Epub 2011 Apr 1.
The actin filament cross-linker L-plastin confers resistance to TNF-alpha in MCF-7 breast cancer cells in a phosphorylation-dependent manner.
- Tumor Immunotherapy and Microenvironment
- Platform LUXGEN - Micro-Array
2010 Jun. J Cell Mol Med.14(6A):1264-75. Epub 2009 Oct 3.
Determination of genes and microRNAs involved in the resistance to fludarabine in vivo in chronic lymphocytic leukemia.
- Tumor Stroma Interactions
- Tumor Immunotherapy and Microenvironment
- Platform LUXGEN - Micro-Array
2010 May. Mol Cancer.9(1):115. emoussay, vpalissot, lvallar, $, $, velkhoury, naouali, kvanmoer, bleners, fbernardin, .amuller, $, $, $, $, evandyck, gberchem.
The histone deacetylase inhibitor MGCD0103 induces apoptosis in B-cell chronic lymphocytic leukemia cells through a mitochondria-mediated caspase activation cascade.
- Tumor Stroma Interactions
- Tumor Immunotherapy and Microenvironment
- Platform National Cytometry
2010 Apr. Mol Cancer Ther.9(5):1349-60. Epub 2010 Apr 20.
Challenges with advanced therapy medicinal products and how to meet them.
- Tumor Immunotherapy and Microenvironment
2010 Mar. Nat Rev Drug Discov.9(3):195-201.
Immune surveillance of human cancer: if the cytotoxic T-lymphocytes play the music, does the tumoral system call the tune?
- Tumor Immunotherapy and Microenvironment
2010 Jan. Tissue Antigens.75(1):1-8.