Latest publications

Targeted proteomics to assess the response to anti-angiogenic treatment in human glioblastoma (GBM).

  • NORLUX Neuro-Oncology Laboratory
  • Proteomics of Cellular Signaling
February 01, 2016
2016 Feb. Mol Cell Proteomics.15(2):481-92. Epub 2015 Aug 4.
By:
  • Demeure K
  • Fack F
  • Duriez E
  • Tiemann K
  • Bernard A
  • Golebiewska A
  • Bougnaud S
  • Bjerkvig R
  • Domon B
  • Niclou SP.
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Transmembrane protein CD9 is glioblastoma biomarker, relevant for maintenance of glioblastoma stem cells.

  • NORLUX Neuro-Oncology Laboratory
January 05, 2016
2016 Jan. Oncotarget.7(1):593-609. Epub 2015 nov 11.
By:
  • Podergajs N
  • Motaln H
  • Rajcevic U
  • Verbovsek U
  • Korsic M
  • Obad N
  • Espedal H
  • Vittori M
  • Herold-Mende C
  • Miletic H
  • Bjerkvig R
  • Turnsek TL.
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Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
December 01, 2015
2015 Dec. Nat Cell Biol.17(12):1556-68. Epub 2015 Nov 23.
By:
  • Tardito S
  • Oudin A
  • Ahmed SU
  • Fack F
  • Keunen O
  • Zheng L
  • Miletic H
  • Sakariassen PO
  • Weinstock A
  • Wagner A
  • Lindsay SL
  • Hock AK
  • Barnett SC
  • Ruppin E
  • Morkve SH
  • Lund-Johansen M
  • Chalmers AJ
  • Bjerkvig R
  • Niclou SP
  • Gottlieb E.
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Intercellular transfer of transferrin receptor by a contact-, Rab8-dependent mechanism involving tunneling nanotubes.

  • NORLUX Neuro-Oncology Laboratory
November 01, 2015
2015 Nov. FASEB J.29(11):4695-712. Epub 2015 Jul 28.
By:
  • Burtey A
  • Wagner M
  • Hodneland E
  • Skaftnesmo KO
  • Schoelermann J
  • Mondragon IR
  • Espedal H
  • Golebiewska A
  • Niclou SP
  • Bjerkvig R
  • Kogel T
  • Gerdes HH.
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Correction: Engraftment of Human Glioblastoma Cells in Immunocompetent Rats through Acquired Immunosuppression.

  • NORLUX Neuro-Oncology Laboratory
October 02, 2015
2015 Oct. PLoS One.10(10):e0140303.
By:
  • Huszthy PC
  • Sakariassen PO
  • Espedal H
  • Brokstad KA
  • Bjerkvig R
  • Miletic H.
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Melanoma brain metastasis is independent of lactate dehydrogenase A expression.

  • NORLUX Neuro-Oncology Laboratory
October 01, 2015
2015 Oct. Neuro Oncol.17(10):1374-85. Epub 2015 Mar 19.
By:
  • Sundstrom T
  • Espedal H
  • Harter PN
  • Fasmer KE
  • Skaftnesmo KO
  • Horn S
  • Hodneland E
  • Mittelbronn M
  • Weide B
  • Beschorner R
  • Bender B
  • Rygh CB
  • Lund-Johansen M
  • Bjerkvig R
  • Thorsen F.
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Engraftment of Human Glioblastoma Cells in Immunocompetent Rats through Acquired Immunosuppression.

  • NORLUX Neuro-Oncology Laboratory
August 20, 2015
2015 Aug. PLoS One.10(8):e0136089.
By:
  • Huszthy PC
  • Sakariassen PO
  • Espedal H
  • Brokstad KA
  • Bjerkvig R
  • Miletic H.
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The pH sensibility of actin-bundling LIM proteins is governed by the acidic properties of their C-terminal domain.

  • Cytoskeleton and Cancer Progression
  • NORLUX Neuro-Oncology Laboratory
  • DNA Repair and Chemoresistance
August 19, 2015
2015 Aug. FEBS Lett.589(18):2312-9. Epub 2015 Jul 29.
By:
  • Moes D
  • Hoffmann C
  • Dieterle M
  • Moreau F
  • Neumann K
  • Papuga J
  • Furtado AT
  • Steinmetz A
  • Thomas C.
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Inference of low and high-grade glioma gene regulatory networks delineates the role of Rnd3 in establishing multiple hallmarks of cancer.

  • NORLUX Neuro-Oncology Laboratory
July 01, 2015
2015 Jul. PLoS Genet.11(7):e1005325.
By:
  • Clarke K
  • Daubon T
  • Turan N
  • Soulet F
  • Mohd Zahari M
  • Ryan KR
  • Durant S
  • He S
  • Herbert J
  • Ankers J
  • Heath JK
  • Bjerkvig R
  • Bicknell R
  • Hotchin NA
  • Bikfalvi A
  • Falciani F.
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Gauging heterogeneity in primary versus recurrent glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
July 01, 2015
2015 Jul. Neuro Oncol.17(7):907-9. Epub 2015 May 12.
By:
  • Niclou SP.
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Effect of endogenous inhibitors of tyrosine kinase receptors on glioma growth: a role for LRIG1? (Doctoral thesis)

  • NORLUX Neuro-Oncology Laboratory
May 22, 2015
2015 May. Luxembourg: Université de Luxembourg 2015. 149 p.
By:
  • Tiemann K.
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Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
  • Platform LUXGEN - Micro-Array
May 01, 2015
2015 May. PLoS One.10(5):e0123544.
By:
  • Sanzey M
  • Abdul Rahim SA
  • Oudin A
  • Dirkse A
  • Kaoma T
  • Vallar L
  • Herold-Mende C
  • Bjerkvig R
  • Golebiewska A
  • Niclou SP.
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OECI-EACR precision medicine for cancer: Conference report 1-4 March 2015, Luxembourg.

  • NORLUX Neuro-Oncology Laboratory
April 03, 2015
2015 Apr. ecancermedicalscience.9:519.
By:
  • Golebiewska A
  • Fritah S
  • Girotti MR.
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Therapeutic control and resistance of the EGFR-driven signaling network in glioblastoma.

  • Computational Biomedicine
  • NORLUX Neuro-Oncology Laboratory
March 31, 2015
2015 Mar. Cell Commun Signal.13(1):23.
By:
  • Azuaje F
  • Tiemann K
  • Niclou SP.
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Whole genomes redefine the mutational landscape of pancreatic cancer.

  • NORLUX Neuro-Oncology Laboratory
February 25, 2015
2015 Feb. Nature.518(7540):495-501.
By:
  • Pajic M
  • Patch AM
  • Chang DK
  • Kassahn KS
  • Bailey P
  • Johns AL
  • Miller D
  • Nones K
  • Quek K
  • Quinn MC
  • Robertson AJ
  • Fadlullah MZ
  • Bruxner TJ
  • Christ AN
  • Harliwong I
  • Idrisoglu S
  • Manning S
  • Nourse C
  • Nourbakhsh E
  • Wani S
  • Wilson PJ
  • Markham E
  • Cloonan N
  • Anderson MJ
  • Fink JL
  • Holmes O
  • Kazakoff SH
  • Leonard C
  • Newell F
  • Poudel B
  • Song S
  • Taylor D
  • Waddell N
  • Wood S
  • Xu Q
  • Wu J
  • Pinese M
  • Cowley MJ
  • Lee HC
  • Jones MD
  • Nagrial AM
  • Humphris J
  • Chantrill LA
  • Chin V
  • Steinmann AM
  • Mawson A
  • Humphrey ES
  • Colvin EK
  • Chou A
  • Scarlett CJ
  • Pinho AV
  • Giry-Laterriere M
  • Rooman I
  • Samra JS
  • Kench JG
  • Pettitt JA
  • Merrett ND
  • Toon C
  • Epari K
  • Nguyen NQ
  • Barbour A
  • Zeps N
  • Jamieson NB
  • Graham JS
  • Niclou SP
  • Bjerkvig R
  • Grutzmann R
  • Aust D
  • Hruban RH
  • Maitra A
  • Iacobuzio-Donahue CA
  • Wolfgang CL
  • Morgan RA
  • Lawlor RT
  • Corbo V
  • Bassi C
  • Falconi M
  • Zamboni G
  • Tortora G
  • Tempero MA
  • Gill AJ
  • Eshleman JR
  • Pilarsky C
  • Scarpa A
  • Musgrove EA
  • Pearson JV
  • Biankin AV
  • Grimmond SM.
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Towards the application of alginate cell microencapsulation technologies to treat brain tumors. (Doctoral thesis)

  • NORLUX Neuro-Oncology Laboratory
February 11, 2015
2015 Feb. Groningen: University of Groningen, 2015. 154 p.
By:
  • Bhujbal SV.
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Axitinib increases the infiltration of immune cells and reduces the suppressive capacity of monocytic MDSCs in an intracranial mouse melanoma model.

  • NORLUX Neuro-Oncology Laboratory
January 22, 2015
2015 Jan. OncoImmunology.4(4):e998107.
By:
  • Du Four S
  • Maenhout SK
  • De Pierre K
  • Renmans D
  • Niclou SP
  • Thielemans K
  • Neyns B
  • Aerts JL.
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A gene mapping bottleneck in the translational route from zebrafish to human.

  • NORLUX Neuro-Oncology Laboratory
January 12, 2015
2015 Jan. Front Genet.5:470.
By:
  • de Klein N
  • Ibberson M
  • Crespo I
  • Rodius S
  • Azuaje F.
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Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
January 01, 2015
2015 Jan. Acta Neuropathol.129(1):115-31. Epub 2014 Oct 17.
By:
  • Fack F
  • Espedal H
  • Keunen O
  • Golebiewska A
  • Obad N
  • Harter PN
  • Mittelbronn M
  • Bahr O
  • Weyerbrock A
  • Stuhr L
  • Miletic H
  • Sakariassen PO
  • Stieber D
  • Rygh CB
  • Lund-Johansen M
  • Zheng L
  • Gottlieb E
  • Niclou SP
  • Bjerkvig R.
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Multimodal imaging of physiologic changes induced by anti-angiogenic therapy in glioblastoma. (Doctoral thesis)

  • NORLUX Neuro-Oncology Laboratory
December 18, 2014
2014 Dec. Bergen: University of Bergen, 2014. 56 (+ References) p.
By:
  • Keunen O.
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