Anaïs Oudin

Latest publications

AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion.

  • NORLUX Neuro-Oncology Laboratory
  • Multiomics Data Science
  • Quantitative Biology Unit
  • Proteomics of Cellular Signaling
December 11, 2020
2020 Dec. Nat Commun.11(1):6366.
By:
  • Schuster A
  • Klein E
  • Neirinckx V
  • Knudsen AM
  • Fabian C
  • Hau AC
  • Dieterle M
  • Oudin A
  • Nazarov PV
  • Golebiewska A
  • Muller A
  • Perez-Hernandez D
  • Rodius S
  • Dittmar G
  • Bjerkvig R
  • Herold-Mende C
  • Klink B
  • Kristensen BW
  • Niclou SP.
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Glioblastoma organoids: Pre-clinical applications and challenges in the context of immunotherapy.

  • NORLUX Neuro-Oncology Laboratory
December 08, 2020
2020 Dec. Front Oncol.10:604121.
By:
  • Klein E
  • Hau AC
  • Oudin A
  • Golebiewska A
  • Niclou SP.
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Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
  • Neuro-Immunology Group
  • Computational Biomedicine
  • Multiomics Data Science
  • Luxembourg Center of Neuropathology
  • Personalized Therapy Discovery
December 01, 2020
2020 Dec. Acta Neuropathol.140(6):919-949. Epub 2020 Oct 3.
By:
  • Golebiewska A
  • Hau AC
  • Oudin A
  • Stieber D
  • Yabo YA
  • Baus V
  • Barthelemy V
  • Klein E
  • Bougnaud S
  • Keunen O
  • Wantz M
  • Michelucci A
  • Neirinckx V
  • Muller A
  • Kaoma T
  • Nazarov PV
  • Azuaje F
  • De Falco A
  • Flies B
  • Richart L
  • Poovathingal S
  • Arns T
  • Grzyb K
  • Mock A
  • Herold-Mende C
  • Steino A
  • Brown D
  • May P
  • Miletic H
  • Malta TM
  • Noushmehr H
  • Kwon YJ
  • Jahn W
  • Klink B
  • Tanner G
  • Stead LF
  • Mittelbronn M
  • Skupin A
  • Hertel F
  • Bjerkvig R
  • Niclou SP.
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Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia.

  • Tumor Stroma Interactions
  • Platform National Cytometry
  • Tumor Immunotherapy and Microenvironment
  • NORLUX Neuro-Oncology Laboratory
  • Allergy and Clinical Immunology
April 05, 2018
2018 Apr. Blood.131(14):1617-1621. Epub 2018 Feb 13.
By:
  • Wierz M
  • Pierson S
  • Guyonnet L
  • Viry E
  • Lequeux A
  • Oudin A
  • Niclou SP
  • Ollert M
  • Berchem G
  • Janji B
  • Guerin C
  • Paggetti J
  • Moussay E.
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Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
  • Computational Biomedicine
December 01, 2017
2017 Dec. EMBO Mol Med.9(12):1681-1695.
By:
  • Fack F
  • Tardito S
  • Hochart G
  • Oudin A
  • Zheng L
  • Fritah S
  • Golebiewska A
  • Nazarov PV
  • Bernard A
  • Hau AC
  • Keunen O
  • Leenders W
  • Lund-Johansen M
  • Stauber J
  • Gottlieb E
  • Bjerkvig R
  • Niclou SP.
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Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A.

  • NORLUX Neuro-Oncology Laboratory
  • Computational Biomedicine
  • Platform LUXGEN - Micro-Array
  • Tumor Immunotherapy and Microenvironment
September 05, 2017
2017 Sep. Br J Cancer.117(6):813-825. Epub 2017 Aug 10.
By:
  • Abdul Rahim SA
  • Dirkse A
  • Oudin A
  • Schuster A
  • Bohler J
  • Barthelemy V
  • Muller A
  • Vallar L
  • Janji B
  • Golebiewska A
  • Niclou SP.
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Aptamer functionalization of nanosystems for glioblastoma targeting through the blood-brain barrier.

  • NORLUX Neuro-Oncology Laboratory
May 25, 2017
2017 May. J Med Chem.60(10):4510-4516. Epub 2017 May 10.
By:
  • Monaco I
  • Camorani S
  • Colecchia D
  • Locatelli E
  • Calandro P
  • Oudin A
  • Niclou S
  • Arra C
  • Chiariello M
  • Cerchia L
  • Comes Franchini M.
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Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
  • Computational Biomedicine
  • Platform LUXGEN - Micro-Array
  • Platform National Cytometry
May 31, 2016
2016 May. Oncotarget.7(22):31955-71.
By:
  • Bougnaud S
  • Golebiewska A
  • Oudin A
  • Keunen O
  • Harter PN
  • Mader L
  • Azuaje F
  • Fritah S
  • Stieber D
  • Kaoma T
  • Vallar L
  • Brons NH
  • Daubon T
  • Miletic H
  • Sundstrom T
  • Herold-Mende C
  • Mittelbronn M
  • Bjerkvig R
  • Niclou SP.
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CRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis.

  • Cytoskeleton and Cancer Progression
  • NORLUX Neuro-Oncology Laboratory
March 22, 2016
2016 Mar. Oncotarget.7(12):13688-705.
By:
  • Hoffmann C
  • Mao X
  • Dieterle M
  • Moreau F
  • Al Absi A
  • Steinmetz A
  • Oudin A
  • Berchem G
  • Janji B
  • Thomas C.
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Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
December 01, 2015
2015 Dec. Nat Cell Biol.17(12):1556-68. Epub 2015 Nov 23.
By:
  • Tardito S
  • Oudin A
  • Ahmed SU
  • Fack F
  • Keunen O
  • Zheng L
  • Miletic H
  • Sakariassen PO
  • Weinstock A
  • Wagner A
  • Lindsay SL
  • Hock AK
  • Barnett SC
  • Ruppin E
  • Morkve SH
  • Lund-Johansen M
  • Chalmers AJ
  • Bjerkvig R
  • Niclou SP
  • Gottlieb E.
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Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
  • Platform LUXGEN - Micro-Array
May 01, 2015
2015 May. PLoS One.10(5):e0123544.
By:
  • Sanzey M
  • Abdul Rahim SA
  • Oudin A
  • Dirkse A
  • Kaoma T
  • Vallar L
  • Herold-Mende C
  • Bjerkvig R
  • Golebiewska A
  • Niclou SP.
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Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes.

  • NORLUX Neuro-Oncology Laboratory
  • Platform National Cytometry
  • Platform LUXGEN - Micro-Array
February 01, 2014
2014 Feb. Acta Neuropathol.127(2):203-1. Epub 2013 Oct 24.
By:
  • Stieber D
  • Golebiewska A
  • Evers L
  • Lenkiewicz E
  • Brons NH
  • Nicot N
  • Oudin A
  • Bougnaud S
  • Hertel F
  • Bjerkvig R
  • Vallar L
  • Barrett MT
  • Niclou SP.
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Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia.

  • Tumor Immunotherapy and Microenvironment
  • NORLUX Neuro-Oncology Laboratory
October 22, 2013
2013 Oct. Proc Natl Acad Sci U S A.110(43):17450-5. Epub 2013 Oct 7.
By:
  • Baginska J
  • Viry E
  • Berchem G
  • Poli A
  • Noman MZ
  • van Moer K
  • Medves S
  • Zimmer J
  • Oudin A
  • Niclou SP
  • Bleackley RC
  • Goping IS
  • Chouaib S
  • Janji B.
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The soluble form of the tumor suppressor Lrig1 potently inhibits in vivo glioma growth irrespective of EGF receptor status.

  • NORLUX Neuro-Oncology Laboratory
September 01, 2013
2013 Sep. Neuro Oncol.15(9):1200-11. Epub 2013 May 30.
By:
  • Johansson M
  • Oudin A
  • Tiemann K
  • Bernard A
  • Golebiewska A
  • Keunen O
  • Fack F
  • Stieber D
  • Wang B
  • Hedman H
  • Niclou SP.
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Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
March 01, 2011
2011 Mar. Proc Natl Acad Sci U S A.108(9):3749-54. Epub 2011 Feb 14.
By:
  • Keunen O
  • Johansson M
  • Oudin A
  • Sanzey M
  • Rahim SA
  • Fack F
  • Thorsen F
  • Taxt T
  • Bartos M
  • Jirik R
  • Miletic H
  • Wang J
  • Stieber D
  • Stuhr L
  • Moen I
  • Rygh CB
  • Bjerkvig R
  • Niclou SP.
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