Michel Mittelbronn
Latest publications
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.
- NORLUX Neuro-Oncology Laboratory
- Translational Radiomics
- Neuro-Immunology Group
- Computational Biomedicine
- Multiomics Data Science
- Luxembourg Center of Neuropathology
- Personalized Therapy Discovery
2020 Dec. Acta Neuropathol.140(6):919-949. Epub 2020 Oct 3.
Improved risk stratification in younger IDH wild-type glioblastoma patients by combining a 4-miRNA signature with MGMT promoter methylation status.
- Luxembourg Center of Neuropathology
2020 Dec. Neurooncol Adv.2(1):vdaa137.
FGFR3 overexpression is a useful detection tool for FGFR3 fusions and sequence variations in glioma.
- Luxembourg Center of Neuropathology
2020 Nov. Neurooncol Pract. Accepted.
Linking epigenetic signature and metabolic phenotype in IDH mutant and IDH wildtype diffuse glioma.
- Luxembourg Center of Neuropathology
2020 Oct. Neuropathol Appl Neurobiol. Online ahead of print.
Cetuximab-mediated protection from hypoxia- induced cell death: implications for therapy sequence in colorectal cancer.
- Luxembourg Center of Neuropathology
2020 Oct. Cancers.12(10).
Blood pressure lowering decreases intracerebral hemorrhage volume and improves behavioral outcomes in experimental animals.
- Luxembourg Center of Neuropathology
2020 Sep. J Stroke.22(3):416-418. Epub 2020 Sep 29.
Pituitary tumor transforming gene 1 orchestrates gene regulatory variation in mouse ventral midbrain during aging.
- Neuro-Immunology Group
- Luxembourg Center of Neuropathology
2020 Sep. Front Genet.11(1119).
Cholinergic innervation and ganglion cell distribution in Hirschsprung's disease.
- Luxembourg Center of Neuropathology
2020 Aug. BMC Pediatr.20(1):399.
Hypoxia-induced autophagy drives colorectal cancer initiation and progression by activating the PRKC/PKC-EZR (ezrin) pathway.
- Tumor Immunotherapy and Microenvironment
- Multiomics Data Science
- Integrated BioBank of Luxembourg
- Luxembourg Center of Neuropathology
2020 Aug. Autophagy.16(8):1436-1452. Epub 2019 Nov 27.
HIF-1alpha is involved in blood-brain barrier dysfunction and paracellular migration of bacteria in pneumococcal meningitis.
- Luxembourg Center of Neuropathology
2020 Aug. Acta Neuropathol.140(2):183-208. Epub 2020 Jun 11.
Parkinson's disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions.
- Integrated BioBank of Luxembourg
- Transversal Translational Medicine
- Deep Digital Phenotyping Research Unit
- PHR Custom Group 2
- Clinical and Epidemiological Investigation Center
- Competence Center for Methodology and Statistics
- Luxembourg Center of Neuropathology
2020 Jun. BMC Biol.18(1):62.
Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors.
- Luxembourg Center of Neuropathology
2020 May. J Clin Invest.130(5):2488-2495.
High density DNA methylation array is a reliable alternative for PCR-based analysis of the MGMT promoter methylation status in glioblastoma.
- Luxembourg Center of Neuropathology
2020 Jan. Pathol Res Pract.216(1):152728. Epub 2019 Nov 11.
Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course.
- Luxembourg Center of Neuropathology
2020 Jan. Acta Neuropathol.139(1):193-209. Epub 2019 Sep 28.
Delay in diagnosing patients with right-sided glioblastoma induced by hemispheric-specific clinical presentation.
- Luxembourg Center of Neuropathology
2020 Jan. J Neurooncol.146(1):63-69. Epub 2019 Nov 11.
Generation of an Atxn2-CAG100 knock-in mouse reveals N-acetylaspartate production deficit due to early Nat8l dysregulation.
- Luxembourg Center of Neuropathology
2019 Dec. Neurobiol Dis.132:104559. Epub 2019 Jul 31.
Impact of Docetaxel on blood-brain barrier function and formation of breast cancer brain metastases.
- Luxembourg Center of Neuropathology
2019 Oct. J Exp Clin Cancer Res.38(1):434.
Lack of H3K27 trimethylation is associated with 1p/19q codeletion in diffuse gliomas.
- Luxembourg Center of Neuropathology
2019 Aug. Acta Neuropathol.138(2):331-334. Epub 2019 May 7.
Mistletoe-based drugs work in synergy with radio-chemotherapy in the treatment of glioma in vitro and in vivo in glioblastoma bearing mice.
- Luxembourg Center of Neuropathology
2019 Jul. Evid Based Complement Alternat Med.2019:2019/07/30.
Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas.
- Luxembourg Center of Neuropathology
- NORLUX Neuro-Oncology Laboratory
- Computational Biomedicine
2019 Jul. Brain Pathol.29(4):513-529. Epub 2019 Jan 15.