Latest publications

Occurrence and congener profiles of polybrominated diphenyl ethers in green mussels (Perna viridis) collected from northern South China Sea and the associated potential health risk.

  • Human Biomonitoring Research Unit
January 01, 2020
2020 Jan. Sci Total Environ.698:134276. Epub 2019 Sep 3.
By:
  • Sun R
  • Pan C
  • Li QX
  • Peng F
  • Mai B.

Multiple pesticides in mothers' hair samples and children's measurements at birth: Results from the French national birth cohort (ELFE).

  • Human Biomonitoring Research Unit
January 01, 2020
2020 Jan. Int J Hyg Environ Health.223(1):22-33. Epub 2019 Nov 8.
By:
  • Beranger R
  • Hardy EM
  • Binter AC
  • Charles MA
  • Zaros C
  • Appenzeller BMR
  • Chevrier C.

Cumulative exposure to organic pollutants of French children assessed by hair analysis.

  • Human Biomonitoring Research Unit
January 01, 2020
2020 Jan. Environ Int.134:105332. Epub 2019 Nov 27.
By:
  • Iglesias-Gonzalez A
  • Hardy EM
  • Appenzeller BMR.

PAHs increase the production of extracellular vesicles both in vitro in endothelial cells and in vivo in urines from rats.

  • Immune Endocrine and Epigenetics
  • Human Biomonitoring Research Unit
December 01, 2019
2019 Dec. Environ Pollut.255(Pt 1):113171. Epub 2019 Sep 10.
By:
  • Le Goff M
  • Lagadic-Gossmann D
  • Latour R
  • Podechard N
  • Grova N
  • Gauffre F
  • Chevance S
  • Burel A
  • Appenzeller BMR
  • Ulmann L
  • Sergent O
  • Le Ferrec E.

Blood pharmacokinetic of 17 common pesticides in mixture following a single oral exposure in rats: implications for human biomonitoring and exposure assessment.

  • Human Biomonitoring Research Unit
  • Competence Center for Methodology and Statistics
October 01, 2019
2019 Oct. Arch Toxicol.93(10):2849-2862. Epub 2019 Aug 19.
By:
  • Chata C
  • Palazzi P
  • Grova N
  • Haan S
  • Emond C
  • Vaillant M
  • Appenzeller BMR.

Human pollution exposure correlates with accelerated ultrastructural degradation of hair fibers.

  • Human Biomonitoring Research Unit
September 10, 2019
2019 Sep. Proc Natl Acad Sci U S A.116(37):18410-18415. Epub 2019 Aug 26.
By:
  • Naudin G
  • Bastien P
  • Mezzache S
  • Trehu E
  • Bourokba N
  • Appenzeller BMR
  • Soeur J
  • Bornschlogl T.

Polycyclic aromatic hydrocarbons can trigger hepatocyte release of extracellular vesicles by various mechanisms of action depending on their affinity for the aryl hydrocarbon receptor.

  • Immune Endocrine and Epigenetics
  • Human Biomonitoring Research Unit
July 31, 2019
2019 Jul. Toxicol Sci. [Epub ahead of print].
By:
  • van Meteren N
  • Lagadic-Gossmann D
  • Chevanne M
  • Gallais I
  • Gobart D
  • Burel A
  • Bucher S
  • Grova N
  • Fromenty B
  • Appenzeller BMR
  • Chevance S
  • Gauffre F
  • Le Ferrec E
  • Sergent O.

Biomonitoring of children exposure to urban pollution and environmental tobacco smoke with hair analysis - A pilot study on children living in Paris and Yeu Island, France.

  • Human Biomonitoring Research Unit
May 15, 2019
2019 May. Sci Total Environ.665:864-872. Epub 2019 Feb 13.
By:
  • Palazzi P
  • Hardy EM
  • Appenzeller BMR.

Challenges and benefits of integrating diverse sampling strategies in the observation of cardiovascular risk factors (ORISCAV-LUX 2) study.

  • Public Health Expertise
  • Public Health Research
  • Competence Center for Methodology and Statistics
  • Human Biomonitoring Research Unit
  • Sports Medicine Research Laboratory
February 04, 2019
2019 Feb. BMC Med Res Methodol.19(1):27.
By:
  • Alkerwi A
  • Pastore J
  • Sauvageot N
  • Coroller GL
  • Bocquet V
  • d'Incau M
  • Aguayo G
  • Appenzeller B
  • Bejko D
  • Bohn T
  • Malisoux L
  • Couffignal S
  • Noppe S
  • Delagardelle C
  • Beissel J
  • Chioti A
  • Stranges S
  • Schmit JC.

Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol: a possible key role for xenobiotic metabolism and nitric oxide.

  • Human Biomonitoring Research Unit
December 01, 2018
2018 Dec. Free Radic Biol Med.129:323-337. Epub 2018 Sep 27.
By:
  • Tete A
  • Gallais I
  • Imran M
  • Chevanne M
  • Liamin M
  • Sparfel L
  • Bucher S
  • Burel A
  • Podechard N
  • Appenzeller BMR
  • Fromenty B
  • Grova N
  • Sergent O
  • Lagadic-Gossmann D.

Exposure to polycyclic aromatic hydrocarbons in women living in the Chinese cities of BaoDing and Dalian revealed by hair analysis.

  • Human Biomonitoring Research Unit
  • Competence Center for Methodology and Statistics
December 01, 2018
2018 Dec. Environ Int.121(Pt 2):1341-1354. Epub 2018 Nov 9.
By:
  • Palazzi P
  • Mezzache S
  • Bourokba N
  • Hardy EM
  • Schritz A
  • Bastien P
  • Emond C
  • Li J
  • Soeur J
  • Appenzeller BMR.

Regulatory identification of BPA as an endocrine disruptor: Context and methodology.

  • Human Biomonitoring Research Unit
November 01, 2018
2018 Nov. Mol Cell Endocrinol.475:4-9. Epub 2018 Feb 6.
By:
  • Beausoleil C
  • Emond C
  • Cravedi JP
  • Antignac JP
  • Applanat M
  • Appenzeller BR
  • Beaudouin R
  • Belzunces LP
  • Canivenc-Lavier MC
  • Chevalier N
  • Chevrier C
  • Elefant E
  • Eustache F
  • Habert R
  • Kolf-Clauw M
  • Le Magueresse-Battistoni B
  • Mhaouty-Kodja S
  • Minier C
  • Multigner L
  • Schroeder H
  • Thonneau P
  • Viguie C
  • Pouzaud F
  • Ormsby JN
  • Rousselle C
  • Verines-Jouin L
  • Pasquier E
  • Michel C.

Hair analysis for the biomonitoring of polycyclic aromatic hydrocarbon exposure: comparison with urinary metabolites and DNA adducts in a rat model.

  • Human Biomonitoring Research Unit
October 01, 2018
2018 Oct. Arch Toxicol.92(10):3061-3075. Epub 2018 Aug 29.
By:
  • Grova N
  • Hardy EM
  • Fays F
  • Duca RC
  • Appenzeller BMR.

Multiple pesticide analysis in hair samples of pregnant French women: Results from the ELFE national birth cohort.

  • Human Biomonitoring Research Unit
September 01, 2018
2018 Sep. Environ Int.120:43-53. Epub 2018 Jul 29.
By:
  • Beranger R
  • Hardy EM
  • Dexet C
  • Guldner L
  • Zaros C
  • Nougadere A
  • Metten MA
  • Chevrier C
  • Appenzeller BMR.

Exposure to polycyclic aromatic hydrocarbons leads to non-monotonic modulation of DNA and RNA (hydroxy)methylation in a rat model.

  • Human Biomonitoring Research Unit
July 12, 2018
2018 Jul. Sci Rep.8(1):10577.
By:
  • Duca RC
  • Grova N
  • Ghosh M
  • Do JM
  • Hoet PHM
  • Vanoirbeek JAJ
  • Appenzeller BMR
  • Godderis L.

Study of the incorporation mechanisms of organic chemicals into hair. (Doctoral thesis)

  • Human Biomonitoring Research Unit
May 29, 2018
2018 May. Luxembourg: Université de Luxembourg, 2018. 215 p.
By:
  • Chata C.

Potential of dynamically harmonized Fourier transform ion cyclotron resonance cell for high-throughput metabolomics fingerprinting: control of data quality.

  • Human Biomonitoring Research Unit
January 01, 2018
2018 Jan. Anal Bioanal Chem.410(2):483-490. Epub 2017 Nov 22.
By:
  • Habchi B
  • Alves S
  • Jouan-Rimbaud Bouveresse D
  • Appenzeller B
  • Paris A
  • Rutledge DN
  • Rathahao-Paris E.

Identification of new tetrahydroxylated metabolites of Polycyclic Aromatic Hydrocarbons in hair as biomarkers of exposure and signature of DNA adduct levels.

  • Human Biomonitoring Research Unit
December 01, 2017
2017 Dec. Anal Chim Acta.995:65-76. Epub 2017 Oct 17.
By:
  • Grova N
  • Antignac JP
  • Hardy EM
  • Monteau F
  • Pouponneau K
  • Le Bizec B
  • Appenzeller BMR.

Genetic and epigenetic alterations in normal and sensitive COPD-diseased human bronchial epithelial cells repeatedly exposed to air pollution-derived PM2.5.

  • Human Biomonitoring Research Unit
October 01, 2017
2017 Oct. Environ Pollut.230:163-177. Epub 2017 Jun 23.
By:
  • Leclercq B
  • Platel A
  • Antherieu S
  • Alleman LY
  • Hardy EM
  • Perdrix E
  • Grova N
  • Riffault V
  • Appenzeller BM
  • Happillon M
  • Nesslany F
  • Coddeville P
  • Lo-Guidice JM
  • Garcon G.

Chemical evaluation of electronic cigarettes: Multicomponent analysis of liquid refills and their corresponding aerosols.

  • Human Biomonitoring Research Unit
October 01, 2017
2017 Oct. J Anal Toxicol.41(8):670-678.
By:
  • Beauval N
  • Antherieu S
  • Soyez M
  • Gengler N
  • Grova N
  • Howsam M
  • Hardy EM
  • Fischer M
  • Appenzeller BMR
  • Goossens JF
  • Allorge D
  • Garcon G
  • Lo-Guidice JM
  • Garat A.