Brice Appenzeller

Latest publications

Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol: a possible key role for xenobiotic metabolism and nitric oxide.

  • Human Biomonitoring Research Unit
December 01, 2018
2018 Dec. Free Radic Biol Med.129:323-337. Epub 2018 Sep 27.
By:
  • Tete A
  • Gallais I
  • Imran M
  • Chevanne M
  • Liamin M
  • Sparfel L
  • Bucher S
  • Burel A
  • Podechard N
  • Appenzeller BMR
  • Fromenty B
  • Grova N
  • Sergent O
  • Lagadic-Gossmann D.
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Regulatory identification of BPA as an endocrine disruptor: Context and methodology.

  • Human Biomonitoring Research Unit
November 01, 2018
2018 Nov. Mol Cell Endocrinol.475:4-9. Epub 2018 Feb 6.
By:
  • Beausoleil C
  • Emond C
  • Cravedi JP
  • Antignac JP
  • Applanat M
  • Appenzeller BR
  • Beaudouin R
  • Belzunces LP
  • Canivenc-Lavier MC
  • Chevalier N
  • Chevrier C
  • Elefant E
  • Eustache F
  • Habert R
  • Kolf-Clauw M
  • Le Magueresse-Battistoni B
  • Mhaouty-Kodja S
  • Minier C
  • Multigner L
  • Schroeder H
  • Thonneau P
  • Viguie C
  • Pouzaud F
  • Ormsby JN
  • Rousselle C
  • Verines-Jouin L
  • Pasquier E
  • Michel C.
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Hair analysis for the biomonitoring of polycyclic aromatic hydrocarbon exposure: comparison with urinary metabolites and DNA adducts in a rat model.

  • Human Biomonitoring Research Unit
October 01, 2018
2018 Oct. Arch Toxicol.92(10):3061-3075. Epub 2018 Aug 29.
By:
  • Grova N
  • Hardy EM
  • Fays F
  • Duca RC
  • Appenzeller BMR.
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Multiple pesticide analysis in hair samples of pregnant French women: Results from the ELFE national birth cohort.

  • Human Biomonitoring Research Unit
September 01, 2018
2018 Sep. Environ Int.120:43-53. Epub 2018 Jul 29.
By:
  • Beranger R
  • Hardy EM
  • Dexet C
  • Guldner L
  • Zaros C
  • Nougadere A
  • Metten MA
  • Chevrier C
  • Appenzeller BMR.
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Exposure to polycyclic aromatic hydrocarbons leads to non-monotonic modulation of DNA and RNA (hydroxy)methylation in a rat model.

  • Human Biomonitoring Research Unit
July 12, 2018
2018 Jul. Sci Rep.8(1):10577.
By:
  • Duca RC
  • Grova N
  • Ghosh M
  • Do JM
  • Hoet PHM
  • Vanoirbeek JAJ
  • Appenzeller BMR
  • Godderis L.
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Potential of dynamically harmonized Fourier transform ion cyclotron resonance cell for high-throughput metabolomics fingerprinting: control of data quality.

  • Human Biomonitoring Research Unit
January 01, 2018
2018 Jan. Anal Bioanal Chem.410(2):483-490. Epub 2017 Nov 22.
By:
  • Habchi B
  • Alves S
  • Jouan-Rimbaud Bouveresse D
  • Appenzeller B
  • Paris A
  • Rutledge DN
  • Rathahao-Paris E.
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Identification of new tetrahydroxylated metabolites of Polycyclic Aromatic Hydrocarbons in hair as biomarkers of exposure and signature of DNA adduct levels.

  • Human Biomonitoring Research Unit
December 01, 2017
2017 Dec. Anal Chim Acta.995:65-76. Epub 2017 Oct 17.
By:
  • Grova N
  • Antignac JP
  • Hardy EM
  • Monteau F
  • Pouponneau K
  • Le Bizec B
  • Appenzeller BMR.
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Genetic and epigenetic alterations in normal and sensitive COPD-diseased human bronchial epithelial cells repeatedly exposed to air pollution-derived PM2.5.

  • Human Biomonitoring Research Unit
October 01, 2017
2017 Oct. Environ Pollut.230:163-177. Epub 2017 Jun 23.
By:
  • Leclercq B
  • Platel A
  • Antherieu S
  • Alleman LY
  • Hardy EM
  • Perdrix E
  • Grova N
  • Riffault V
  • Appenzeller BM
  • Happillon M
  • Nesslany F
  • Coddeville P
  • Lo-Guidice JM
  • Garcon G.
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Chemical evaluation of electronic cigarettes: Multicomponent analysis of liquid refills and their corresponding aerosols.

  • Human Biomonitoring Research Unit
October 01, 2017
2017 Oct. J Anal Toxicol.41(8):670-678.
By:
  • Beauval N
  • Antherieu S
  • Soyez M
  • Gengler N
  • Grova N
  • Howsam M
  • Hardy EM
  • Fischer M
  • Appenzeller BMR
  • Goossens JF
  • Allorge D
  • Garcon G
  • Lo-Guidice JM
  • Garat A.
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New insights into urine-based assessment of polycyclic aromatic hydrocarbon-exposure from a rat model: Identification of relevant metabolites and influence of elimination kinetics.

  • Human Biomonitoring Research Unit
September 01, 2017
2017 Sep. Environ Pollut.228:484-495. Epub 2017 May 30.
By:
  • Grova N
  • Fays F
  • Hardy EM
  • Appenzeller BMR.
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Hair analysis for the biomonitoring of pesticide exposure: comparison with blood and urine in a rat model.

  • Human Biomonitoring Research Unit
  • Competence Center for Methodology and Statistics
August 01, 2017
2017 Aug. Arch Toxicol.91(8):2813-2825. Epub 2016 Dec 23.
By:
  • Appenzeller BMR
  • Hardy EM
  • Grova N
  • Chata C
  • Fays F
  • Briand O
  • Schroeder H
  • Duca RC.
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Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype.

  • Human Biomonitoring Research Unit
March 15, 2017
2017 Mar. Sci Rep.7(1):195.
By:
  • Hardonniere K
  • Fernier M
  • Gallais I
  • Mograbi B
  • Podechard N
  • Le Ferrec E
  • Grova N
  • Appenzeller B
  • Burel A
  • Chevanne M
  • Sergent O
  • Huc L
  • Bortoli S
  • Lagadic-Gossmann D.
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Differential responses of healthy and chronic obstructive pulmonary diseased human bronchial epithelial cells repeatedly exposed to air pollution-derived PM4.

  • Human Biomonitoring Research Unit
November 01, 2016
2016 Nov. Environ Pollut.218:1074-1088. Epub 2016 Sep 1.
By:
  • Leclercq B
  • Happillon M
  • Antherieu S
  • Hardy EM
  • Alleman LY
  • Grova N
  • Perdrix E
  • Appenzeller BM
  • Lo Guidice JM
  • Coddeville P
  • Garcon G.
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Epigenetic changes upon multi-residue exposure to polycyclic aromatic hydrocarbons.

  • Human Biomonitoring Research Unit
June 01, 2016
2016 Jun. Proceeding Organohalogen Compounds Database.78:845-847.
By:
  • Duca R
  • Grova N
  • Ghosh M
  • Appenzeller BM
  • Vanoirbeek J
  • Godderis L.
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Influence of pesticide physicochemical properties on the association between plasma and hair concentration.

  • Human Biomonitoring Research Unit
May 01, 2016
2016 May. Anal Bioanal Chem.408(13):3601-12. Epub 2016 Mar 11.
By:
  • Chata C
  • Hardy EM
  • Grova N
  • Appenzeller BM.
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Behavioral toxicity and physiological changes from repeated exposure to fluorene administered orally or intraperitoneally to adult male Wistar rats: A dose-response study.

  • Human Biomonitoring Research Unit
March 01, 2016
2016 Mar. Neurotoxicology.53:321-33. Epub 2015 Nov 23.
By:
  • Peiffer J
  • Grova N
  • Hidalgo S
  • Salquebre G
  • Rychen G
  • Bisson JF
  • Appenzeller BM
  • Schroeder H.
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TETROLS, Detection of Tetrols of polycyclic aromatic hydrocarbons in hair as biomarkers of exposure and signature of DNA-adduct level, Funding: ADEME project 2014-2015: Final report. (Book)

  • Human Biomonitoring Research Unit
March 01, 2016
2016 Mar. Angers: ADEME, 2017. In press
By:
  • Grova N
  • Antignac JP
  • Lebizec B
  • Appenzeller BM.
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Pesticide detection in air samples from contrasted houses and in their inhabitants' hair.

  • Human Biomonitoring Research Unit
February 15, 2016
2016 Feb. Sci Total Environ.544:845-52. Epub 2015 Dec 17.
By:
  • Raeppel C
  • Salquebre G
  • Millet M
  • Appenzeller BM.
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Multi-residue analysis of organic pollutants in hair and urine for matrices comparison.

  • Human Biomonitoring Research Unit
April 01, 2015
2015 Apr. Forensic Sci Int.249:6-19. Epub 2014 Dec 13.
By:
  • Hardy EM
  • Duca RC
  • Salquebre G
  • Appenzeller BM.
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Analysis of airborne pesticides from different chemical classes adsorbed on Radiello(R) Tenax(R) passive tubes by thermal-desorption-GC/MS.

  • Human Biomonitoring Research Unit
February 01, 2015
2015 Feb. Environ Sci Pollut Res Int.22(4):2726-34. Epub 2014 Sep 11.
By:
  • Raeppel C
  • Fabritius M
  • Nief M
  • Appenzeller BM
  • Briand O
  • Tuduri L
  • Millet M.
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