Latest publications

Purification of leukemia-derived exosomes to study microenvironment modulation.

  • National Cytometry Platform
January 01, 2019
2019 Jan. Methods Mol Biol.1884:231-245.
By:
  • Wierz M
  • Pierson S
  • Gargiulo E
  • Guerin C
  • Moussay E
  • Paggetti J.

Actin cytoskeleton remodeling drives breast cancer cell escape from natural killer-mediated cytotoxicity.

  • Cytoskeleton and Cancer Progression
  • National Cytometry Platform
  • NORLUX-Glioma Biology
  • Tumor Microenvironment
October 01, 2018
2018 Oct. Cancer Res.78(19):5631-5643. Epub 2018 Aug 13.
By:
  • Al Absi A
  • Wurzer H
  • Guerin C
  • Hoffmann C
  • Moreau F
  • Mao X
  • Brown-Clay J
  • Petrolli R
  • Casellas CP
  • Dieterle M
  • Thiery JP
  • Chouaib S
  • Berchem G
  • Janji B
  • Thomas C.

Intra-cardiac release of extracellular vesicles shapes inflammation following myocardial infarction.

  • National Cytometry Platform
June 22, 2018
2018 Jun. Circ Res.123(1):100-106. Epub 2018 Mar 28.
By:
  • Loyer X
  • Zlatanova I
  • Devue C
  • Yin M
  • Howangyin KY
  • Klaihmon P
  • Guerin CL
  • Kheloufi M
  • Vilar J
  • Zannis K
  • Fleischmann BK
  • Hwang DW
  • Park J
  • Lee H
  • Menasche P
  • Silvestre JS
  • Boulanger CM.

Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia.

  • National Cytometry Platform
  • Tumor Microenvironment
  • NORLUX-Glioma Biology
  • Allergy and Clinical Immunology
April 05, 2018
2018 Apr. Blood.131(14):1617-1621. Epub 2018 Feb 13.
By:
  • Wierz M
  • Pierson S
  • Guyonnet L
  • Viry E
  • Lequeux A
  • Oudin A
  • Niclou SP
  • Ollert M
  • Berchem G
  • Janji B
  • Guerin C
  • Paggetti J
  • Moussay E.

Endothelial microparticles are associated to pathogenesis of idiopathic pulmonary fibrosis.

  • National Cytometry Platform
April 01, 2018
2018 Apr. Stem Cell Rev.14(2):223-235.
By:
  • Bacha NC
  • Blandinieres A
  • Rossi E
  • Gendron N
  • Nevo N
  • Lecourt S
  • Guerin CL
  • Renard JM
  • Gaussem P
  • Angles-Cano E
  • Boulanger CM
  • Israel-Biet D
  • Smadja DM.

Egfl7 Represses the Vasculogenic Potential of Human Endothelial Progenitor Cells.

  • National Cytometry Platform
February 01, 2018
2018 Feb. Stem Cell Rev.14(1):82-91.
By:
  • d'Audigier C
  • Susen S
  • Blandinieres A
  • Mattot V
  • Saubamea B
  • Rossi E
  • Nevo N
  • Lecourt S
  • Guerin CL
  • Dizier B
  • Gendron N
  • Caetano B
  • Gaussem P
  • Soncin F
  • Smadja DM.

The high molecular weight dipeptidyl peptidase IV Pol d 3 is a major allergen of Polistes dominula venom.

  • Molecular and Translational Allergology
  • National Cytometry Platform
  • Allergy and Clinical Immunology
January 22, 2018
2018 Jan. Sci Rep.8(1):1318.
By:
  • Schiener M
  • Hilger C
  • Eberlein B
  • Pascal M
  • Kuehn A
  • Revets D
  • Planchon S
  • Pietsch G
  • Serrano P
  • Moreno-Aguilar C
  • de la Roca F
  • Biedermann T
  • Darsow U
  • Schmidt-Weber CB
  • Ollert M
  • Blank S.

Selective EGF-Receptor Inhibition in CD4(+) T Cells Induces Anergy and Limits Atherosclerosis.

  • National Cytometry Platform
January 16, 2018
2018 Jan. J Am Coll Cardiol.71(2):160-172.
By:
  • Zeboudj L
  • Maitre M
  • Guyonnet L
  • Laurans L
  • Joffre J
  • Lemarie J
  • Bourcier S
  • Nour-Eldine W
  • Guerin C
  • Friard J
  • Wakkach A
  • Fabre E
  • Tedgui A
  • Mallat Z
  • Tharaux PL
  • Ait-Oufella H.

Bone marrow-derived mesenchymal stem cell-loaded fibrin patches act as a reservoir of paracrine factors in chronic myocardial infarction.

  • National Cytometry Platform
December 01, 2017
2017 Dec. J Tissue Eng Regen Med.11(12):3417-3427. Epub 2017 Feb 3.
By:
  • Blondiaux E
  • Pidial L
  • Autret G
  • Rahmi G
  • Balvay D
  • Audureau E
  • Wilhelm C
  • Guerin CL
  • Bruneval P
  • Silvestre JS
  • Menasche P
  • Clement O.

Endothelial Epas1 deficiency Is sufficient to promote parietal epithelial cell activation and FSGS in experimental hypertension.

  • National Cytometry Platform
December 01, 2017
2017 Dec. J Am Soc Nephrol.28(12):3563-3578. Epub 2017 Sep 19.
By:
  • Luque Y
  • Lenoir O
  • Bonnin P
  • Hardy L
  • Chipont A
  • Placier S
  • Vandermeersch S
  • Xu-Dubois YC
  • Robin B
  • Lazareth H
  • Souyri M
  • Guyonnet L
  • Baudrie V
  • Camerer E
  • Rondeau E
  • Mesnard L
  • Tharaux PL.

Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner.

  • Tumor Microenvironment
  • National Cytometry Platform
October 31, 2017
2017 Oct. Proc Natl Acad Sci U S A.114(44):E9271-E9279. Epub 2017 Oct 16.
By:
  • Mgrditchian T
  • Arakelian T
  • Paggetti J
  • Noman MZ
  • Viry E
  • Moussay E
  • Van Moer K
  • Kreis S
  • Guerin C
  • Buart S
  • Robert C
  • Borg C
  • Vielh P
  • Chouaib S
  • Berchem G
  • Janji B.

Co-injection of mesenchymal stem cells with endothelial progenitor cells accelerates muscle recovery in hind limb ischemia through an endoglin-dependent mechanism.

  • National Cytometry Platform
October 05, 2017
2017 Oct. Thromb Haemost.117(10):1908-1918. Epub 2017 Aug 3.
By:
  • Rossi E
  • Smadja D
  • Goyard C
  • Cras A
  • Dizier B
  • Bacha N
  • Lokajczyk A
  • Guerin CL
  • Gendron N
  • Planquette B
  • Mignon V
  • Bernabeu C
  • Sanchez O
  • Smadja DM.

Very small embryonic-like stem cells are mobilized in human peripheral blood during hypoxemic COPD exacerbations and pulmonary hypertension.

  • National Cytometry Platform
August 01, 2017
2017 Aug. Stem Cell Rev.13(4):561-566.
By:
  • Guerin CL
  • Blandinieres A
  • Planquette B
  • Silvestre JS
  • Israel-Biet D
  • Sanchez O
  • Smadja DM.

Human very small embryonic-like cells support vascular maturation and therapeutic revascularization induced by endothelial progenitor cells.

  • National Cytometry Platform
August 01, 2017
2017 Aug. Stem Cell Rev.13(4):552-560.
By:
  • Guerin CL
  • Rossi E
  • Saubamea B
  • Cras A
  • Mignon V
  • Silvestre JS
  • Smadja DM.

The endothelin B receptor plays a crucial role in the adhesion of neutrophils to the endothelium in sickle cell disease.

  • National Cytometry Platform
July 01, 2017
2017 Jul. Haematologica.102(7):1161-1172. Epub 2017 Apr 6.
By:
  • Koehl B
  • Nivoit P
  • El Nemer W
  • Lenoir O
  • Hermand P
  • Pereira C
  • Brousse V
  • Guyonnet L
  • Ghinatti G
  • Benkerrou M
  • Colin Y
  • Le Van Kim C
  • Tharaux PL.

Tumour-associated glial host cells display a stem-like phenotype with a distinct gene expression profile and promote growth of GBM xenografts.

  • National Cytometry Platform
February 17, 2017
2017 Feb. BMC Cancer.17(1):108.
By:
  • Leiss L
  • Mutlu E
  • Oyan A
  • Yan T
  • Tsinkalovsky O
  • Sleire L
  • Petersen K
  • Rahman MA
  • Johannessen M
  • Mitra SS
  • Jacobsen HK
  • Talasila KM
  • Miletic H
  • Jonassen I
  • Li X
  • Brons NH
  • Kalland KH
  • Wang J
  • Enger PO.

Maintenance therapy with histamine plus IL-2 induces a striking expansion of two CD56bright NK cell subpopulations in patients with acute myeloid leukemia and supports their activation.

  • National Cytometry Platform
  • Innate Cellular Immunity and Chronic Inflammation
July 19, 2016
2016 Jul. Oncotarget.7(29):46466-46481.
By:
  • Cuapio A
  • Post M
  • Cerny-Reiterer S
  • Gleixner KV
  • Stefanzl G
  • Basilio J
  • Herndlhofer S
  • Sperr WR
  • Brons NH
  • Casanova E
  • Zimmer J
  • Valent P
  • Hofer E.

Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction.

  • National Cytometry Platform
June 27, 2016
2016 Jun. J Exp Med.213(7):1353-74.
By:
  • Ngkelo A
  • Richart A
  • Kirk JA
  • Bonnin P
  • Vilar J
  • Lemitre M
  • Marck P
  • Branchereau M
  • Le Gall S
  • Renault N
  • Guerin C
  • Ranek MJ
  • Kervadec A
  • Danelli L
  • Gautier G
  • Blank U
  • Launay P
  • Camerer E
  • Bruneval P
  • Menasche P
  • Heymes C
  • Luche E
  • Casteilla L
  • Cousin B
  • Rodewald HR
  • Kass DA
  • Silvestre JS.

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma.

  • NORLUX-Glioma Biology
  • In vivo imaging facility
  • Bioinformatics and Modelling
  • Genomics Center
  • National Cytometry Platform
May 31, 2016
2016 May. Oncotarget.7(22):31955-71.
By:
  • Bougnaud S
  • Golebiewska A
  • Oudin A
  • Keunen O
  • Harter PN
  • Mader L
  • Azuaje F
  • Fritah S
  • Stieber D
  • Kaoma T
  • Vallar L
  • Brons NH
  • Daubon T
  • Miletic H
  • Sundstrom T
  • Herold-Mende C
  • Mittelbronn M
  • Bjerkvig R
  • Niclou SP.

Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-Cell chronic lymphocytic leukemia.

  • National Cytometry Platform
  • NORLUX-Glioma Biology
August 01, 2014
2014 Aug. Leukemia.28(8):1636-46. Epub 2014 Jan 14.
By:
  • El-Khoury V
  • Pierson S
  • Szwarcbart E
  • Brons NH
  • Roland O
  • Cherrier-De Wilde S
  • Plawny L
  • Van Dyck E
  • Berchem G.