Latest publications
In vivo crystals reveal critical features of the interaction between cystic fibrosis transmembrane conductance regulator (CFTR) and the PDZ2 domain of Na(+)/H(+) exchange cofactor NHERF1.
- Proteomics of Cellular Signaling
2020 Apr. J Biol Chem.295(14):4464-4476. Epub 2020 Feb 2.
Analysis of ubiquitin signaling and chain topology cross-talk.
- Proteomics of Cellular Signaling
2020 Mar. J Proteomics.215:103634. Epub 2020 Jan 7.
Hypoxia-Induced Adaptations of miRNomes and Proteomes in Melanoma Cells and Their Secreted Extracellular Vesicles.
- Proteomics of Cellular Signaling
- Quantitative Biology Unit
2020 Mar. Cancers.12(3).
Fisetin protects against cardiac cell death through reduction of ROS production and caspases activity.
- Proteomics of Cellular Signaling
- Quantitative Biology Unit
- NORLUX Neuro-Oncology Laboratory
- Computational Biomedicine
2020 Feb. Sci Rep.10(1):2896.
Linear ubiquitin chains: Cellular functions and strategies for detection and quantification.
- Proteomics of Cellular Signaling
2020 Jan. Front Chem.7:915.
Dual role of a GTPase conformational switch for membrane fusion by mitofusin ubiquitylation.
- Proteomics of Cellular Signaling
2020 Jan. Life Sci Alliance.3(1):e201900476.
Endothelial PKA activity regulates angiogenesis by limiting autophagy through phosphorylation of ATG16L1.
- Proteomics of Cellular Signaling
2019 Oct. Elife.8.
Connecting histopathology imaging and proteomics in kidney cancer through machine learning.
- Multiomics Data Science
- Proteomics of Cellular Signaling
2019 Sep. J Clin Med.8(10).
Deconvolution of transcriptomes and miRNomes by independent component analysis provides insights into biological processes and clinical outcomes of melanoma patients.
- Multiomics Data Science
- Computational Biomedicine
- Proteomics of Cellular Signaling
2019 Sep. BMC Med Genomics.12(1):132.
DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.
- Proteomics of Cellular Signaling
2019 Sep. J Cell Sci.132(17).
An integrated workflow for crosslinking mass spectrometry.
- Proteomics of Cellular Signaling
2019 Sep. Mol Syst Biol.15(9):e8994.
A protein quality control pathway regulated by linear ubiquitination.
- Proteomics of Cellular Signaling
2019 May. EMBO J.38(9). Epub 2019 Mar 18.
Deregulated splicing is a major mechanism of RNA-Induced toxicity in Huntington's disease.
- Proteomics of Cellular Signaling
2019 Apr. J Mol Biol.431(9):1869-1877. Epub 2019 Jan 31.
Assessment of ubiquitin chain topology by targeted mass spectrometry.
- Proteomics of Cellular Signaling
2019 Apr. Methods Mol Biol.1977:25-34.
PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPbeta.
- Proteomics of Cellular Signaling
2019 Mar. iScience.13:351-370. Epub 2019 Mar 1.
The lipid head group is the key element for substrate recognition by the P4 ATPase ALA2, a phosphatidylserine flippase.
- Proteomics of Cellular Signaling
2019 Mar. Biochem J.476(5):783-794.
SorCS2 controls functional expression of amino acid transporter EAAT3 and protects neurons from oxidative stress and epilepsy-induced pathology.
- Proteomics of Cellular Signaling
2019 Mar. Cell Rep.26(10):2792-2804 e6.
Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress.
- Proteomics of Cellular Signaling
2019 Feb. Sci Rep.9(1):3183.
On the relation between filament density, force generation, and protrusion rate in mesenchymal cell motility.
- Proteomics of Cellular Signaling
2018 Nov. Mol Biol Cell.29(22):2674-2686. Epub 2018 Aug 29.
A new ALK isoform transported by extracellular vesicles confers drug resistance to melanoma cells.
- Proteomics of Cellular Signaling
2018 Oct. Mol Cancer.17(1):145.