Gunnar Dittmar

Latest publications

In silico approach for validating and unveiling new applications for prognostic biomarkers of endometrial cancer.

  • Proteomics of Cellular Signaling
  • Multiomics Data Science
October 09, 2021
2021 Oct. Cancers.13(20):5052.
By:
  • Coll-de la Rubia E
  • Martinez-Garcia E
  • Dittmar G
  • Nazarov PV
  • Bebia V
  • Cabrera S
  • Gil-Moreno A
  • Colás E.

Integrative genomics analysis of nasal intestinal-type adenocarcinomas demonstrates the major role of CACNA1C and paves the way for a simple diagnostic tool in male woodworkers.

  • Proteomics of Cellular Signaling
September 25, 2021
2021 Sep. Clin Epigenetics.13(1):179.
By:
  • Gallet P
  • Oussalah A
  • Pouget C
  • Dittmar G
  • Chery C
  • Gauchotte G
  • Jankowski R
  • Gueant JL
  • Houlgatte R.

An antigen microarray protocol for COVID-19 serological analysis.

  • Experimental and Molecular Immunology
  • Proteomics of Cellular Signaling
September 17, 2021
2021 Sep. STAR Protoc.2(3):100815. Epub 2021 Aug 26.
By:
  • Longworth J
  • Dittmar G.

Peptide array-based interactomics.

  • Proteomics of Cellular Signaling
September 01, 2021
2021 Sep. Anal Bioanal Chem.413(22):5561-5566. Epub 2021 May 3.
By:
  • Hernandez DP
  • Dittmar G.

A universal peptide matrix interactomics approach to disclose motif-dependent protein binding.

  • Proteomics of Cellular Signaling
August 13, 2021
2021 Aug. Mol Cell Proteomics.20:100135. Online ahead of print.
By:
  • Ramberger E
  • Suarez-Artiles L
  • Perez-Hernandez D
  • Haji M
  • Popp O
  • Reimer U
  • Leutz A
  • Dittmar G
  • Mertins P.

The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis.

  • Proteomics of Cellular Signaling
August 01, 2021
2021 Aug. Oncogene.(34):5286-5301. Epub 2021 Jul 10.
By:
  • Kobelt D
  • Perez-Hernandez D
  • Fleuter C
  • Dahlmann M
  • Zincke F
  • Smith J
  • Migotti R
  • Popp O
  • Burock S
  • Walther W
  • Dittmar G
  • Mertins P
  • Stein U.

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPalpha.

  • Quantitative Biology Unit
  • Multiomics Data Science
  • Proteomics of Cellular Signaling
June 25, 2021
2021 Jun. iScience.24(6):102686.
By:
  • Ramberger E
  • Sapozhnikova V
  • Kowenz-Leutz E
  • Zimmermann K
  • Nicot N
  • Nazarov PV
  • Perez-Hernandez D
  • Reimer U
  • Mertins P
  • Dittmar G
  • Leutz A.

Cystathionine-gamma-lyase drives antioxidant defense in cysteine-restricted IDH1-mutant astrocytomas.

  • NORLUX Neuro-Oncology Laboratory
  • Proteomics of Cellular Signaling
  • Quantitative Biology Unit
  • Cancer Metabolism Group
April 09, 2021
2021 Apr. Neurooncol Adv.3(1):vdab057.
By:
  • Cano-Galiano A
  • Oudin A
  • Fack F
  • Allega MF
  • Sumpton D
  • Martinez-Garcia E
  • Dittmar G
  • Hau AC
  • De Falco A
  • Herold-Mende C
  • Bjerkvig R
  • Meiser J
  • Tardito S
  • Niclou SP.

MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer.

  • Proteomics of Cellular Signaling
April 01, 2021
2021 Apr. Cell Mol Life Sci.78(7):3525-3542. Epub 2021 Jan 20.
By:
  • Imbastari F
  • Dahlmann M
  • Sporbert A
  • Mattioli CC
  • Mari T
  • Scholz F
  • Timm L
  • Twamley S
  • Migotti R
  • Walther W
  • Dittmar G
  • Rehm A
  • Stein U.

Analysis of the dynamic proteasome structure by cross-linking mass spectrometry.

  • Proteomics of Cellular Signaling
  • Quantitative Biology Unit
March 27, 2021
2021 Mar. Biomolecules.11(4):505.
By:
  • Mendes ML
  • Dittmar G.

New insights into the organization and regulation of the apical polarity network in mammalian epithelial cells.

  • Proteomics of Cellular Signaling
  • Quantitative Biology Unit
January 14, 2021
2021 Jan. FEBS J. Online ahead of print.
By:
  • Martin E
  • Girardello R
  • Dittmar G
  • Ludwig A.

Functional significance of conserved cysteines in the extracellular loops of the ATP binding cassette transporter Pdr11p.

  • Proteomics of Cellular Signaling
December 22, 2020
2020 Dec. J Fungi.7(1):2.
By:
  • Stanchev LD
  • Marek M
  • Xian F
  • Klohn M
  • Silvestro D
  • Dittmar G
  • Lopez-Marques RL
  • Gunther Pomorski T.

AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion.

  • NORLUX Neuro-Oncology Laboratory
  • Multiomics Data Science
  • Quantitative Biology Unit
  • Proteomics of Cellular Signaling
December 11, 2020
2020 Dec. Nat Commun.11(1):6366.
By:
  • Schuster A
  • Klein E
  • Neirinckx V
  • Knudsen AM
  • Fabian C
  • Hau AC
  • Dieterle M
  • Oudin A
  • Nazarov PV
  • Golebiewska A
  • Muller A
  • Perez-Hernandez D
  • Rodius S
  • Dittmar G
  • Bjerkvig R
  • Herold-Mende C
  • Klink B
  • Kristensen BW
  • Niclou SP.

The proteasome activators Blm10/PA200 enhance the proteasomal degradation of N-terminal Huntingtin.

  • Proteomics of Cellular Signaling
November 20, 2020
2020 Nov. Biomolecules.10(11).
By:
  • Aladdin A
  • Yao Y
  • Yang C
  • Kahlert G
  • Ghani M
  • Kiraly N
  • Boratko A
  • Uray K
  • Dittmar G
  • Tar K.

Hub genes in a pan-cancer co-expression network show potential for predicting drug responses.

  • Computational Biomedicine
  • NORLUX Neuro-Oncology Laboratory
  • Proteomics of Cellular Signaling
July 30, 2020
2020 Jul. F1000Res.7:1906.
By:
  • Azuaje F
  • Kaoma T
  • Jeanty C
  • Nazarov PV
  • Muller A
  • Kim SY
  • Dittmar G
  • Golebiewska A
  • Niclou SP.

Prognostic biomarkers in endometrial cancer: A systematic review and meta-analysis.

  • Proteomics of Cellular Signaling
June 17, 2020
2020 Jun. J Clin Med.9(6).
By:
  • Coll-de la Rubia E
  • Martinez-Garcia E
  • Dittmar G
  • Gil-Moreno A
  • Cabrera S
  • Colas E.

Ubiquitin chain analysis by parallel reaction monitoring.

  • Quantitative Biology Unit
  • Proteomics of Cellular Signaling
June 17, 2020
2020 Jun. J Vis Exp.(160).
By:
  • Longworth J
  • Mendes ML
  • Dittmar G.

Influence of wood species on toxicity of log-wood stove combustion aerosols: a parallel animal and air-liquid interface cell exposure study on spruce and pine smoke.

  • Proteomics of Cellular Signaling
June 15, 2020
2020 Jun. Part Fibre Toxicol.17(1):27.
By:
  • Ihantola T
  • Di Bucchianico S
  • Happo M
  • Ihalainen M
  • Uski O
  • Bauer S
  • Kuuspalo K
  • Sippula O
  • Tissari J
  • Oeder S
  • Hartikainen A
  • Ronkko TJ
  • Martikainen MV
  • Huttunen K
  • Vartiainen P
  • Suhonen H
  • Kortelainen M
  • Lamberg H
  • Leskinen A
  • Sklorz M
  • Michalke B
  • Dilger M
  • Weiss C
  • Dittmar G
  • Beckers J
  • Irmler M
  • Buters J
  • Candeias J
  • Czech H
  • Yli-Pirila P
  • Abbaszade G
  • Jakobi G
  • Orasche J
  • Schnelle-Kreis J
  • Kanashova T
  • Karg E
  • Streibel T
  • Passig J
  • Hakkarainen H
  • Jokiniemi J
  • Zimmermann R
  • Hirvonen MR
  • Jalava PI.

Branching and mixing: New signals of the ubiquitin signaling system. In Ubiquitin: Proteasome pathway. (Book Chapter)

  • Quantitative Biology Unit
  • Proteomics of Cellular Signaling
May 21, 2020
2020 May. Zhan X, ed. London: IntechOpen, 2020. ISBN 978-1-83880-841-9; 978-1-83880-432-9 (Print); 978-1-83880-842-6 (eBook PDF).
By:
  • Perez-Hernandez D
  • Mendes ML
  • Dittmar G.

Analysis of ubiquitin signaling and chain topology cross-talk.

  • Proteomics of Cellular Signaling
March 20, 2020
2020 Mar. J Proteomics.215:103634. Epub 2020 Jan 7.
By:
  • Mendes ML
  • Fougeras MR
  • Dittmar G.