Latest publications

Analysis of the dynamic proteasome structure by cross-linking mass spectrometry.

  • Proteomics of Cellular Signaling
  • Quantitative Biology Unit
March 27, 2021
2021 Mar. Biomolecules.11(4):505.
By:
  • Mendes ML
  • Dittmar G.

MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer.

  • Proteomics of Cellular Signaling
January 20, 2021
2021 Jan. Cell Mol Life Sci. Online ahead of print.
By:
  • Imbastari F
  • Dahlmann M
  • Sporbert A
  • Mattioli CC
  • Mari T
  • Scholz F
  • Timm L
  • Twamley S
  • Migotti R
  • Walther W
  • Dittmar G
  • Rehm A
  • Stein U.

New insights into the organization and regulation of the apical polarity network in mammalian epithelial cells.

  • Proteomics of Cellular Signaling
  • Quantitative Biology Unit
January 14, 2021
2021 Jan. FEBS J. Online ahead of print.
By:
  • Martin E
  • Girardello R
  • Dittmar G
  • Ludwig A.

Functional significance of conserved cysteines in the extracellular loops of the ATP binding cassette transporter Pdr11p.

  • Proteomics of Cellular Signaling
December 22, 2020
2020 Dec. J Fungi.7(1):2.
By:
  • Stanchev LD
  • Marek M
  • Xian F
  • Klohn M
  • Silvestro D
  • Dittmar G
  • Lopez-Marques RL
  • Gunther Pomorski T.

AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion.

  • NORLUX Neuro-Oncology Laboratory
  • Multiomics Data Science
  • Quantitative Biology Unit
  • Proteomics of Cellular Signaling
December 11, 2020
2020 Dec. Nat Commun.11(1):6366.
By:
  • Schuster A
  • Klein E
  • Neirinckx V
  • Knudsen AM
  • Fabian C
  • Hau AC
  • Dieterle M
  • Oudin A
  • Nazarov PV
  • Golebiewska A
  • Muller A
  • Perez-Hernandez D
  • Rodius S
  • Dittmar G
  • Bjerkvig R
  • Herold-Mende C
  • Klink B
  • Kristensen BW
  • Niclou SP.

The proteasome activators Blm10/PA200 enhance the proteasomal degradation of N-terminal Huntingtin.

  • Proteomics of Cellular Signaling
November 20, 2020
2020 Nov. Biomolecules.10(11).
By:
  • Aladdin A
  • Yao Y
  • Yang C
  • Kahlert G
  • Ghani M
  • Kiraly N
  • Boratko A
  • Uray K
  • Dittmar G
  • Tar K.

Nanomaterials and annelid immunity: A comparative survey to reveal the common stress and defense responses of two sentinel species to nanomaterials in the environment.

  • Proteomics of Cellular Signaling
September 23, 2020
2020 Sep. Biology.9(10).
By:
  • Bodo K
  • Baranzini N
  • Girardello R
  • Kokhanyuk B
  • Nemeth P
  • Hayashi Y
  • Grimaldi A
  • Engelmann P.

Hub genes in a pan-cancer co-expression network show potential for predicting drug responses.

  • Computational Biomedicine
  • NORLUX Neuro-Oncology Laboratory
  • Proteomics of Cellular Signaling
July 30, 2020
2020 Jul. F1000Res.7:1906.
By:
  • Azuaje F
  • Kaoma T
  • Jeanty C
  • Nazarov PV
  • Muller A
  • Kim SY
  • Dittmar G
  • Golebiewska A
  • Niclou SP.

Prognostic biomarkers in endometrial cancer: A systematic review and meta-analysis.

  • Proteomics of Cellular Signaling
June 17, 2020
2020 Jun. J Clin Med.9(6).
By:
  • Coll-de la Rubia E
  • Martinez-Garcia E
  • Dittmar G
  • Gil-Moreno A
  • Cabrera S
  • Colas E.

Ubiquitin chain analysis by parallel reaction monitoring.

  • Quantitative Biology Unit
  • Proteomics of Cellular Signaling
June 17, 2020
2020 Jun. J Vis Exp.(160).
By:
  • Longworth J
  • Mendes ML
  • Dittmar G.

Influence of wood species on toxicity of log-wood stove combustion aerosols: a parallel animal and air-liquid interface cell exposure study on spruce and pine smoke.

  • Proteomics of Cellular Signaling
June 15, 2020
2020 Jun. Part Fibre Toxicol.17(1):27.
By:
  • Ihantola T
  • Di Bucchianico S
  • Happo M
  • Ihalainen M
  • Uski O
  • Bauer S
  • Kuuspalo K
  • Sippula O
  • Tissari J
  • Oeder S
  • Hartikainen A
  • Ronkko TJ
  • Martikainen MV
  • Huttunen K
  • Vartiainen P
  • Suhonen H
  • Kortelainen M
  • Lamberg H
  • Leskinen A
  • Sklorz M
  • Michalke B
  • Dilger M
  • Weiss C
  • Dittmar G
  • Beckers J
  • Irmler M
  • Buters J
  • Candeias J
  • Czech H
  • Yli-Pirila P
  • Abbaszade G
  • Jakobi G
  • Orasche J
  • Schnelle-Kreis J
  • Kanashova T
  • Karg E
  • Streibel T
  • Passig J
  • Hakkarainen H
  • Jokiniemi J
  • Zimmermann R
  • Hirvonen MR
  • Jalava PI.

In vivo crystals reveal critical features of the interaction between cystic fibrosis transmembrane conductance regulator (CFTR) and the PDZ2 domain of Na(+)/H(+) exchange cofactor NHERF1.

  • Proteomics of Cellular Signaling
April 03, 2020
2020 Apr. J Biol Chem.295(14):4464-4476. Epub 2020 Feb 2.
By:
  • Martin ER
  • Barbieri A
  • Ford RC
  • Robinson RC.

Analysis of ubiquitin signaling and chain topology cross-talk.

  • Proteomics of Cellular Signaling
March 20, 2020
2020 Mar. J Proteomics.215:103634. Epub 2020 Jan 7.
By:
  • Mendes ML
  • Fougeras MR
  • Dittmar G.

Hypoxia-Induced Adaptations of miRNomes and Proteomes in Melanoma Cells and Their Secreted Extracellular Vesicles.

  • Proteomics of Cellular Signaling
  • Quantitative Biology Unit
March 14, 2020
2020 Mar. Cancers.12(3).
By:
  • Walbrecq G
  • Lecha O
  • Gaigneaux A
  • Fougeras MR
  • Philippidou D
  • Margue C
  • Tetsi Nomigni M
  • Bernardin F
  • Dittmar G
  • Behrmann I
  • Kreis S.

Fisetin protects against cardiac cell death through reduction of ROS production and caspases activity.

  • Proteomics of Cellular Signaling
  • Quantitative Biology Unit
  • NORLUX Neuro-Oncology Laboratory
  • Computational Biomedicine
February 19, 2020
2020 Feb. Sci Rep.10(1):2896.
By:
  • Rodius S
  • de Klein N
  • Jeanty C
  • Sanchez-Iranzo H
  • Crespo I
  • Ibberson M
  • Xenarios I
  • Dittmar G
  • Mercader N
  • Niclou SP
  • Azuaje F.

Linear ubiquitin chains: Cellular functions and strategies for detection and quantification.

  • Proteomics of Cellular Signaling
January 10, 2020
2020 Jan. Front Chem.7:915.
By:
  • Dittmar G
  • Winklhofer KF.

Dual role of a GTPase conformational switch for membrane fusion by mitofusin ubiquitylation.

  • Proteomics of Cellular Signaling
January 01, 2020
2020 Jan. Life Sci Alliance.3(1):e201900476.
By:
  • Schuster R
  • Anton V
  • Simoes T
  • Altin S
  • den Brave F
  • Hermanns T
  • Hospenthal M
  • Komander D
  • Dittmar G
  • Dohmen RJ
  • Escobar-Henriques M.

Endothelial PKA activity regulates angiogenesis by limiting autophagy through phosphorylation of ATG16L1.

  • Proteomics of Cellular Signaling
October 03, 2019
2019 Oct. Elife.8.
By:
  • Zhao X
  • Nedvetsky P
  • Stanchi F
  • Vion AC
  • Popp O
  • Zuhlke K
  • Dittmar G
  • Klussmann E
  • Gerhardt H.

Connecting histopathology imaging and proteomics in kidney cancer through machine learning.

  • Multiomics Data Science
  • Proteomics of Cellular Signaling
September 25, 2019
2019 Sep. J Clin Med.8(10).
By:
  • Azuaje F
  • Kim SY
  • Perez Hernandez D
  • Dittmar G.

Deconvolution of transcriptomes and miRNomes by independent component analysis provides insights into biological processes and clinical outcomes of melanoma patients.

  • Multiomics Data Science
  • Computational Biomedicine
  • Proteomics of Cellular Signaling
September 18, 2019
2019 Sep. BMC Med Genomics.12(1):132.
By:
  • Nazarov PV
  • Wienecke-Baldacchino AK
  • Zinovyev A
  • Czerwinska U
  • Muller A
  • Nashan D
  • Dittmar G
  • Azuaje F
  • Kreis S.