Simone Niclou
Latest publications
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.
- NORLUX Neuro-Oncology Laboratory
2021 Jan. Nat Genet.53(1):86-99. Epub 2021 Jan 7.
AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion.
- NORLUX Neuro-Oncology Laboratory
- Multiomics Data Science
- Quantitative Biology Unit
- Proteomics of Cellular Signaling
2020 Dec. Nat Commun.11(1):6366.
Glioblastoma organoids: Pre-clinical applications and challenges in the context of immunotherapy.
- NORLUX Neuro-Oncology Laboratory
2020 Dec. Front Oncol.10:604121.
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.
- NORLUX Neuro-Oncology Laboratory
- Translational Radiomics
- Neuro-Immunology Group
- Computational Biomedicine
- Multiomics Data Science
- Luxembourg Center of Neuropathology
- Personalized Therapy Discovery
2020 Dec. Acta Neuropathol.140(6):919-949. Epub 2020 Oct 3.
New hints towards a precision medicine strategy for IDH wild-type glioblastoma.
- NORLUX Neuro-Oncology Laboratory
2020 Dec. Ann Oncol.31(12):1679-1692. Epub 2020 Sep 9.
Temozolomide-induced RNA interactome uncovers novel lncRNA regulatory loops in glioblastoma.
- NORLUX Neuro-Oncology Laboratory
- Quantitative Biology Unit
- DNA Repair and Chemoresistance
2020 Sep. Cancers.12(9).
Hub genes in a pan-cancer co-expression network show potential for predicting drug responses.
- Computational Biomedicine
- NORLUX Neuro-Oncology Laboratory
- Proteomics of Cellular Signaling
2020 Jul. F1000Res.7:1906.
Is there a prominent role for MR spectroscopy in the clinical management of brain tumors?
- Translational Radiomics
- NORLUX Neuro-Oncology Laboratory
2020 Jul. Neuro Oncol.22(7):903-904.
Dual blockade of STAT3 and EGFR: a key to unlock drug resistance in glioblastoma?
- NORLUX Neuro-Oncology Laboratory
2020 Apr. Neuro Oncol.22(4):440-441.
Gender issues from the perspective of health-care professionals in Neuro-oncology: an EANO and EORTC Brain Tumor Group survey.
- NORLUX Neuro-Oncology Laboratory
2020 Mar. Neurooncol Pract.7(2):249-259. Epub 2020 Jan 10.
Fisetin protects against cardiac cell death through reduction of ROS production and caspases activity.
- Proteomics of Cellular Signaling
- Quantitative Biology Unit
- NORLUX Neuro-Oncology Laboratory
- Computational Biomedicine
2020 Feb. Sci Rep.10(1):2896.
Revealing and harnessing tumour-associated microglia/macrophage heterogeneity in glioblastoma.
- Neuro-Immunology Group
- NORLUX Neuro-Oncology Laboratory
2020 Jan. Int J Mol Sci.21(3):E689.
Mutant IDH1 differently affects redox state and metabolism in glial cells of normal and tumor origin.
- NORLUX Neuro-Oncology Laboratory
2019 Dec. Cancers.11(12):2028.
Longitudinal molecular trajectories of diffuse glioma in adults.
- NORLUX Neuro-Oncology Laboratory
2019 Dec. Nature.576(7785):112-120. Epub 2019 Nov 20.
The soluble form of pan-RTK inhibitor and tumor suppressor LRIG1 mediates downregulation of AXL through direct protein-protein interaction in glioblastoma.
- NORLUX Neuro-Oncology Laboratory
- Multiomics Data Science
- Immuno-Pharmacology and Interactomics
2019 Sep. Neurooncol Adv.1(1):vdz024.
Highlights of the inaugural ten - the launch of Neuro-Oncology Advances.
- NORLUX Neuro-Oncology Laboratory
2019 Aug. Neurooncol Adv.1(1):vdz016.
Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas.
- Luxembourg Center of Neuropathology
- NORLUX Neuro-Oncology Laboratory
- Computational Biomedicine
2019 Jul. Brain Pathol.29(4):513-529. Epub 2019 Jan 15.
The distinct roles of CXCR3 variants and their ligands in the tumor microenvironment.
- Immuno-Pharmacology and Interactomics
- Tumor Immunotherapy and Microenvironment
- NORLUX Neuro-Oncology Laboratory
2019 Jun. Cells.8(6).
Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment.
- NORLUX Neuro-Oncology Laboratory
- Computational Biomedicine
- Competence Center for Methodology and Statistics
- Platform National Cytometry
2019 Apr. Nat Commun.10(1):1787.
Irradiation to improve the response to immunotherapeutic agents in glioblastomas.
- NORLUX Neuro-Oncology Laboratory
2019 Apr. Adv Radiat Oncol.4(2):268-282.