Sabrina Fritah

Latest publications

Temozolomide-induced RNA interactome uncovers novel lncRNA regulatory loops in glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
  • Quantitative Biology Unit
  • DNA Repair and Chemoresistance
September 10, 2020
2020 Sep. Cancers.12(9).
By:
  • Fritah S
  • Muller A
  • Jiang W
  • Mitra R
  • Sarmini M
  • Dieterle M
  • Golebiewska A
  • Ye T
  • Van Dyck E
  • Herold-Mende C
  • Zhao Z
  • Azuaje F
  • Niclou SP.

Dual blockade of STAT3 and EGFR: a key to unlock drug resistance in glioblastoma?

  • NORLUX Neuro-Oncology Laboratory
April 15, 2020
2020 Apr. Neuro Oncol.22(4):440-441.
By:
  • Fritah S
  • Niclou SP.

Interfering with long non-coding RNA MIR22HG processing inhibits glioblastoma progression through suppression of Wnt/beta-catenin signalling.

  • NORLUX Neuro-Oncology Laboratory
February 01, 2020
2020 Feb. Brain.143(2):512-530.
By:
  • Han M
  • Wang S
  • Fritah S
  • Wang X
  • Zhou W
  • Yang N
  • Ni S
  • Huang B
  • Chen A
  • Li G
  • Miletic H
  • Thorsen F
  • Bjerkvig R
  • Li X
  • Wang J.

The soluble form of pan-RTK inhibitor and tumor suppressor LRIG1 mediates downregulation of AXL through direct protein-protein interaction in glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
  • Multiomics Data Science
  • Immuno-Pharmacology and Interactomics
September 06, 2019
2019 Sep. Neurooncol Adv.1(1):vdz024.
By:
  • Neirinckx V
  • Hau AC
  • Schuster A
  • Fritah S
  • Tiemann K
  • Klein E
  • Nazarov PV
  • Matagne A
  • Szpakowska M
  • Meyrath M
  • Chevigne A
  • Schmidt MHH
  • Niclou SP.

Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment.

  • NORLUX Neuro-Oncology Laboratory
  • Computational Biomedicine
  • Competence Center for Methodology and Statistics
  • Platform National Cytometry
April 16, 2019
2019 Apr. Nat Commun.10(1):1787.
By:
  • Dirkse A
  • Golebiewska A
  • Buder T
  • Nazarov PV
  • Muller A
  • Poovathingal S
  • Brons NHC
  • Leite S
  • Sauvageot N
  • Sarkisjan D
  • Seyfrid M
  • Fritah S
  • Stieber D
  • Michelucci A
  • Hertel F
  • Herold-Mende C
  • Azuaje F
  • Skupin A
  • Bjerkvig R
  • Deutsch A
  • Voss-Bohme A
  • Niclou SP.

RNAi/CRISPR Screens: from a Pool to a Valid Hit.

  • NORLUX Neuro-Oncology Laboratory
  • Computational Biomedicine
  • DNA Repair and Chemoresistance
January 01, 2019
2019 Jan. Trends Biotechnol.37(1):38-55. Epub 2018 Aug 31.
By:
  • Schuster A
  • Erasimus H
  • Fritah S
  • Nazarov PV
  • van Dyck E
  • Niclou SP
  • Golebiewska A.

Shigella entry unveils a calcium/calpain-dependent mechanism for inhibiting sumoylation.

  • NORLUX Neuro-Oncology Laboratory
December 12, 2017
2017 Dec. Elife.6:e27444.
By:
  • Lapaquette P
  • Fritah S
  • Lhocine N
  • Andrieux A
  • Nigro G
  • Mounier J
  • Sansonetti P
  • Dejean A.

Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
  • Computational Biomedicine
December 01, 2017
2017 Dec. EMBO Mol Med.9(12):1681-1695.
By:
  • Fack F
  • Tardito S
  • Hochart G
  • Oudin A
  • Zheng L
  • Fritah S
  • Golebiewska A
  • Nazarov PV
  • Bernard A
  • Hau AC
  • Keunen O
  • Leenders W
  • Lund-Johansen M
  • Stauber J
  • Gottlieb E
  • Bjerkvig R
  • Niclou SP.

The angiogenic switch leads to a metabolic shift in human glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
  • Computational Biomedicine
  • Platform LUXGEN - Micro-Array
March 01, 2017
2017 Mar. Neuro Oncol.19(3):383-393.
By:
  • Talasila KM
  • Rosland GV
  • Hagland HR
  • Eskilsson E
  • Flones IH
  • Fritah S
  • Azuaje F
  • Atai N
  • Harter PN
  • Mittelbronn M
  • Andersen M
  • Joseph JV
  • Hossain JA
  • Vallar L
  • Noorden CJ
  • Niclou SP
  • Thorsen F
  • Tronstad KJ
  • Tzoulis C
  • Bjerkvig R
  • Miletic H.

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
December 01, 2016
2016 Dec. Neuro Oncol.18(12):1644-1655. Epub 2016 Jun 10.
By:
  • Eskilsson E
  • Rosland GV
  • Talasila KM
  • Knappskog S
  • Keunen O
  • Sottoriva A
  • Foerster S
  • Solecki G
  • Taxt T
  • Jirik R
  • Fritah S
  • Harter PN
  • Valk K
  • Al Hossain J
  • Joseph JV
  • Jahedi R
  • Saed HS
  • Piccirillo SG
  • Spiteri I
  • Leiss L
  • Euskirchen P
  • Graziani G
  • Daubon T
  • Lund-Johansen M
  • Enger PO
  • Winkler F
  • Ritter CA
  • Niclou SP
  • Watts C
  • Bjerkvig R
  • Miletic H.

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
  • Computational Biomedicine
  • Platform LUXGEN - Micro-Array
  • Platform National Cytometry
May 31, 2016
2016 May. Oncotarget.7(22):31955-71.
By:
  • Bougnaud S
  • Golebiewska A
  • Oudin A
  • Keunen O
  • Harter PN
  • Mader L
  • Azuaje F
  • Fritah S
  • Stieber D
  • Kaoma T
  • Vallar L
  • Brons NH
  • Daubon T
  • Miletic H
  • Sundstrom T
  • Herold-Mende C
  • Mittelbronn M
  • Bjerkvig R
  • Niclou SP.

OECI-EACR precision medicine for cancer: Conference report 1-4 March 2015, Luxembourg.

  • NORLUX Neuro-Oncology Laboratory
April 03, 2015
2015 Apr. ecancermedicalscience.9:519.
By:
  • Golebiewska A
  • Fritah S
  • Girotti MR.

Databases for lncRNAs: a comparative evaluation of emerging tools.

  • NORLUX Neuro-Oncology Laboratory
November 01, 2014
2014 Nov. RNA.20(11):1655-65.
By:
  • Fritah S
  • Niclou SP
  • Azuaje F.

Sumoylation controls host anti-bacterial response to the gut invasive pathogen Shigella flexneri.

  • NORLUX Neuro-Oncology Laboratory
September 01, 2014
2014 Sep. EMBO Rep.15(9):965-72. Epub 2014 Aug 5.
By:
  • Fritah S
  • Lhocine N
  • Golebiowski F
  • Mounier J
  • Andrieux A
  • Jouvion G
  • Hay RT
  • Sansonetti P
  • Dejean A.