Petr Nazarov

Latest publications

A DNA repair and cell-cycle gene expression signature in primary and recurrent glioblastoma: prognostic value and clinical implications.

  • DNA Repair and Chemoresistance
  • Computational Biomedicine
  • NORLUX Neuro-Oncology Laboratory
March 15, 2019
2019 Mar. Cancer Res.79(6):1226-1238. Epub 2019 Jan 23.
By:
  • Gobin M
  • Nazarov PV
  • Warta R
  • Timmer M
  • Reifenberger G
  • Felsberg J
  • Vallar L
  • Chalmers AJ
  • Herold-Mende CC
  • Goldbrunner R
  • Niclou SP
  • Van Dyck E.

Tumor suppressor miR-215 counteracts hypoxia-induced colon cancer stem cell activity.

  • Multiomics Data Science
February 18, 2019
2019 Feb. Cancer Lett.450:32-41. Epub 2019 Feb 18.
By:
  • Ullmann P
  • Nurmik M
  • Schmitz M
  • Rodriguez F
  • Weiler J
  • Qureshi-Baig K
  • Felten P
  • Nazarov PV
  • Nicot N
  • Zuegel N
  • Haan S
  • Letellier E.

RNAi/CRISPR Screens: from a Pool to a Valid Hit.

  • NORLUX Neuro-Oncology Laboratory
  • Computational Biomedicine
  • DNA Repair and Chemoresistance
January 01, 2019
2019 Jan. Trends Biotechnol.37(1):38-55. Epub 2018 Aug 31.
By:
  • Schuster A
  • Erasimus H
  • Fritah S
  • Nazarov PV
  • van Dyck E
  • Niclou SP
  • Golebiewska A.

Cytokine-mediated modulation of the hepatic miRNome: miR-146b-5p is an IL-6-inducible miRNA with multiple targets.

  • Computational Biomedicine
November 01, 2018
2018 Nov. J Leukoc Biol.104(5):987-1002. Epub 2018 Aug 26.
By:
  • Kirchmeyer M
  • Servais FA
  • Hamdorf M
  • Nazarov PV
  • Ginolhac A
  • Halder R
  • Vallar L
  • Glanemann M
  • Rubie C
  • Lammert F
  • Kreis S
  • Behrmann I.

The PD-L1- and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by alpha-PD-L1 or alpha-IL6 antibodies.

  • Multiomics Data Science
November 01, 2018
2018 Nov. J Leukoc Biol.104(5):969-985. Epub 2018 Jul 24.
By:
  • Rolvering C
  • Zimmer AD
  • Ginolhac A
  • Margue C
  • Kirchmeyer M
  • Servais F
  • Hermanns HM
  • Hergovits S
  • Nazarov PV
  • Nicot N
  • Kreis S
  • Haan S
  • Behrmann I
  • Haan C.

Identification of beta-arrestin-1 as a diagnostic biomarker in lung cancer.

  • Proteomics of Cellular Signaling
  • Competence Center for Methodology and Statistics
  • Computational Biomedicine
  • Clinical and Epidemiological Investigation Center
  • Integrated BioBank of Luxembourg
August 06, 2018
2018 Aug. Br J Cancer.119(5):580-590. Epub 2018 Aug 6.
By:
  • El-Khoury V
  • Beland M
  • Schritz A
  • Kim SY
  • Nazarov PV
  • Gaboury L
  • Sertamo K
  • Bernardin F
  • Batutu R
  • Antunes L
  • Bennett CW
  • Fays F
  • Berchem G
  • Kim YJ.

Predicting clinical outcome of neuroblastoma patients using an integrative network-based approach.

  • Computational Biomedicine
June 07, 2018
2018 Jun. Biol Direct.13(1):12.
By:
  • Tranchevent LC
  • Nazarov PV
  • Kaoma T
  • Schmartz GP
  • Muller A
  • Kim SY
  • Rajapakse JC
  • Azuaje F.

Transcriptional variations in the wider peritumoral tissue environment of pancreatic cancer.

  • Computational Biomedicine
  • Platform LUXGEN - Micro-Array
March 01, 2018
2018 Mar. Int J Cancer.142(5):1010-1021. Epub 2017 Oct 17.
By:
  • Bauer AS
  • Nazarov PV
  • Giese NA
  • Beghelli S
  • Heller A
  • Greenhalf W
  • Costello E
  • Muller A
  • Bier M
  • Strobel O
  • Hackert T
  • Vallar L
  • Scarpa A
  • Buchler MW
  • Neoptolemos JP
  • Kreis S
  • Hoheisel JD.

Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
  • Computational Biomedicine
December 01, 2017
2017 Dec. EMBO Mol Med.9(12):1681-1695.
By:
  • Fack F
  • Tardito S
  • Hochart G
  • Oudin A
  • Zheng L
  • Fritah S
  • Golebiewska A
  • Nazarov PV
  • Bernard A
  • Hau AC
  • Keunen O
  • Leenders W
  • Lund-Johansen M
  • Stauber J
  • Gottlieb E
  • Bjerkvig R
  • Niclou SP.

RNA sequencing and transcriptome arrays analyses show opposing results for alternative splicing in patient derived samples.

  • Computational Biomedicine
  • Platform LUXGEN - Micro-Array
  • Proteomics of Cellular Signaling
June 06, 2017
2017 Jun. BMC Genomics.18(1):443.
By:
  • Nazarov PV
  • Muller A
  • Kaoma T
  • Nicot N
  • Maximo C
  • Birembaut P
  • Tran NL
  • Dittmar G
  • Vallar L.

Crosstalk between different family members: IL27 recapitulates IFNgamma responses in HCC cells, but is inhibited by IL6-type cytokines.

  • Multiomics Data Science
March 01, 2017
2017 Mar. Biochim Biophys Acta-Mol Cell Res.1864(3):516-526. Epub 2016 Dec 9.
By:
  • Rolvering C
  • Zimmer AD
  • Kozar I
  • Hermanns HM
  • Letellier E
  • Vallar L
  • Nazarov PV
  • Nicot N
  • Ginolhac A
  • Haan S
  • Behrmann I
  • Haan C.

Insights into ligand stimulation effects on gastro-intestinal stromal tumors signalling.

  • Platform LUXGEN - Micro-Array
January 01, 2017
2017 Jan. Cell Signal.29:138-149. Epub 2016 Oct 21.
By:
  • Bahlawane C
  • Schmitz M
  • Letellier E
  • Arumugam K
  • Nicot N
  • Nazarov PV
  • Haan S.

Data on quantification of signaling pathways activated by KIT and PDGFRA mutants.

  • Platform LUXGEN - Micro-Array
December 01, 2016
2016 Dec. Data Brief.9:828-838.
By:
  • Bahlawane C
  • Schmitz M
  • Letellier E
  • Arumugam K
  • Nicot N
  • Nazarov PV
  • Haan S.

Analysis of the dynamic co-expression network of heart regeneration in the zebrafish.

  • Computational Biomedicine
  • Platform LUXGEN - Micro-Array
  • NORLUX Neuro-Oncology Laboratory
May 31, 2016
2016 May. Sci Rep.6:26822.
By:
  • Rodius S
  • Androsova G
  • Gotz L
  • Liechti R
  • Crespo I
  • Merz S
  • Nazarov PV
  • de Klein N
  • Jeanty C
  • Gonzalez-Rosa JM
  • Muller A
  • Bernardin F
  • Niclou SP
  • Vallar L
  • Mercader N
  • Ibberson M
  • Xenarios I
  • Azuaje F.

What do we learn from spheroid culture systems? Insights from tumorspheres derived from primary colon cancer tissue.

  • Integrated BioBank of Luxembourg
  • Multiomics Data Science
January 08, 2016
2016 Jan. PLoS One.11(1):e0146052.
By:
  • Qureshi-Baig K
  • Ullmann P
  • Rodriguez F
  • Frasquilho S
  • Nazarov PV
  • Haan S
  • Letellier E.

Decoding of exon splicing patterns in the human RUNX1-RUNX1T1 fusion gene.

  • Platform LUXGEN - Micro-Array
November 01, 2015
2015 Nov. Int J Biochem Cell Biol.68:48-58. Epub 2015 Aug 29.
By:
  • Grinev VV
  • Migas AA
  • Kirsanava AD
  • Mishkova OA
  • Siomava N
  • Ramanouskaya TV
  • Vaitsiankova AV
  • Ilyushonak IM
  • Nazarov PV
  • Vallar L
  • Aleinikova OV.

Whole transcriptome microarrays identify long non-coding RNAs associated with cardiac hypertrophy.

  • Cardiovascular Research Unit
  • Platform LUXGEN - Micro-Array
September 01, 2015
2015 Sep. Genom Data.5:68-71.
By:
  • Zhang L
  • Hamad EA
  • Vausort M
  • Funakoshi H
  • Nicot N
  • Nazarov PV
  • Vallar L
  • Feldman AM
  • Wagner DR
  • Devaux Y
  • Cardiolinc network.

The oncogenic FIP1L1-PDGFRalpha fusion protein displays skewed signaling properties compared to its wild-type PDGFRalpha counterpart.

  • Platform LUXGEN - Micro-Array
July 17, 2015
2015 Jul. Jakstat.4(1):e1062596.
By:
  • Haan S
  • Bahlawane C
  • Wang J
  • Nazarov PV
  • Muller A
  • Eulenfeld R
  • Haan C
  • Rolvering C
  • Vallar L
  • Satagopam VP
  • Sauter T
  • Wiesinger MY.

Constitutive activation of oncogenic PDGFRalpha-mutant proteins occurring in GIST patients induces receptor mislocalisation and alters PDGFRalpha signalling characteristics.

  • Platform LUXGEN - Micro-Array
March 31, 2015
2015 Mar. Cell Commun Signal.13:21.
By:
  • Bahlawane C
  • Eulenfeld R
  • Wiesinger MY
  • Wang J
  • Muller A
  • Girod A
  • Nazarov PV
  • Felsch K
  • Vallar L
  • Sauter T
  • Satagopam VP
  • Haan S.

Transcriptional response to cardiac injury in the zebrafish: systematic identification of genes with highly concordant activity across in vivo models.

  • NORLUX Neuro-Oncology Laboratory
  • Platform LUXGEN - Micro-Array
October 03, 2014
2014 Oct. BMC Genomics.15(1):852.
By:
  • Rodius S
  • Nazarov PV
  • Nepomuceno-Chamorro IA
  • Jeanty C
  • Gonzalez-Rosa JM
  • Ibberson M
  • da Costa RM
  • Xenarios I
  • Mercader N
  • Azuaje F.