Nathalie Grova

Latest publications

N6-methyladenine in eukaryotic DNA: tissue distribution, early embryo development and neuronal toxicity.

  • Immune Endocrine and Epigenetics
  • Quantitative Biology Unit
  • Cardiovascular Research Unit
April 12, 2021
2021 Apr. Front Genet. Accepted.
By:
  • Fernandes SB
  • Grova N
  • Roth S
  • Duca RC
  • Godderis L
  • Guebels P
  • Mériaux S
  • Lumley A
  • Bouillaud P
  • Ernens I
  • Devaux Y
  • Schroeder H
  • Turner JD.

Assessment of 9-OH- and 7,8-diol-benzo[a]pyrene in blood as potent markers of cognitive impairment related to benzo[a]pyrene exposure: An animal model study.

  • Immune Endocrine and Epigenetics
  • Experimental and Molecular Immunology
  • Clinical and Applied Virology
March 08, 2021
2021 Mar. Toxics.9(3):50.
By:
  • Cherif LS
  • Cao-Lei L
  • Farinelle S
  • Muller CP
  • Turner JD
  • Schroeder H
  • Grova N.

The COVID-19 pandemic: Does our early life environment, life trajectory and socioeconomic status determine disease susceptibility and severity?

  • Immune Endocrine and Epigenetics
July 19, 2020
2020 Jul. Int J Mol Sci.21(14):E5094.
By:
  • Holuka C
  • Merz MP
  • Fernandes SB
  • Charalambous EG
  • Seal SV
  • Grova N
  • Turner JD.

Ultra performance liquid chromatography - tandem mass spectrometer method applied to the analysis of both thyroid and steroid hormones in human hair.

  • Immune Endocrine and Epigenetics
  • Human Biomonitoring Research Unit
February 08, 2020
2020 Feb. J Chromatogr A.1612:460648. Epub 2019 Oct 26.
By:
  • Grova N
  • Wang X
  • Hardy EM
  • Palazzi P
  • Chata C
  • Appenzeller BMR.

PAHs increase the production of extracellular vesicles both in vitro in endothelial cells and in vivo in urines from rats.

  • Immune Endocrine and Epigenetics
  • Human Biomonitoring Research Unit
December 01, 2019
2019 Dec. Environ Pollut.255(Pt 1):113171. Epub 2019 Sep 10.
By:
  • Le Goff M
  • Lagadic-Gossmann D
  • Latour R
  • Podechard N
  • Grova N
  • Gauffre F
  • Chevance S
  • Burel A
  • Appenzeller BMR
  • Ulmann L
  • Sergent O
  • Le Ferrec E.

Blood pharmacokinetic of 17 common pesticides in mixture following a single oral exposure in rats: implications for human biomonitoring and exposure assessment.

  • Human Biomonitoring Research Unit
  • Competence Center for Methodology and Statistics
October 01, 2019
2019 Oct. Arch Toxicol.93(10):2849-2862. Epub 2019 Aug 19.
By:
  • Chata C
  • Palazzi P
  • Grova N
  • Haan S
  • Emond C
  • Vaillant M
  • Appenzeller BMR.

Polycyclic aromatic hydrocarbons can trigger hepatocyte release of extracellular vesicles by various mechanisms of action depending on their affinity for the aryl hydrocarbon receptor.

  • Immune Endocrine and Epigenetics
  • Human Biomonitoring Research Unit
July 31, 2019
2019 Jul. Toxicol Sci. [Epub ahead of print].
By:
  • van Meteren N
  • Lagadic-Gossmann D
  • Chevanne M
  • Gallais I
  • Gobart D
  • Burel A
  • Bucher S
  • Grova N
  • Fromenty B
  • Appenzeller BMR
  • Chevance S
  • Gauffre F
  • Le Ferrec E
  • Sergent O.

Epigenetic and neurological impairments associated with early life exposure to persistent organic pollutants.

  • Immune Endocrine and Epigenetics
January 14, 2019
2019 Jan. Int J Genomics.2019:2085496.
By:
  • Grova N
  • Schroeder H
  • Olivier JL
  • Turner JD.

Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol: a possible key role for xenobiotic metabolism and nitric oxide.

  • Human Biomonitoring Research Unit
December 01, 2018
2018 Dec. Free Radic Biol Med.129:323-337. Epub 2018 Sep 27.
By:
  • Tete A
  • Gallais I
  • Imran M
  • Chevanne M
  • Liamin M
  • Sparfel L
  • Bucher S
  • Burel A
  • Podechard N
  • Appenzeller BMR
  • Fromenty B
  • Grova N
  • Sergent O
  • Lagadic-Gossmann D.

Hair analysis for the biomonitoring of polycyclic aromatic hydrocarbon exposure: comparison with urinary metabolites and DNA adducts in a rat model.

  • Human Biomonitoring Research Unit
October 01, 2018
2018 Oct. Arch Toxicol.92(10):3061-3075. Epub 2018 Aug 29.
By:
  • Grova N
  • Hardy EM
  • Fays F
  • Duca RC
  • Appenzeller BMR.

Exposure to polycyclic aromatic hydrocarbons leads to non-monotonic modulation of DNA and RNA (hydroxy)methylation in a rat model.

  • Human Biomonitoring Research Unit
July 12, 2018
2018 Jul. Sci Rep.8(1):10577.
By:
  • Duca RC
  • Grova N
  • Ghosh M
  • Do JM
  • Hoet PHM
  • Vanoirbeek JAJ
  • Appenzeller BMR
  • Godderis L.

Identification of new tetrahydroxylated metabolites of Polycyclic Aromatic Hydrocarbons in hair as biomarkers of exposure and signature of DNA adduct levels.

  • Human Biomonitoring Research Unit
December 01, 2017
2017 Dec. Anal Chim Acta.995:65-76. Epub 2017 Oct 17.
By:
  • Grova N
  • Antignac JP
  • Hardy EM
  • Monteau F
  • Pouponneau K
  • Le Bizec B
  • Appenzeller BMR.

Genetic and epigenetic alterations in normal and sensitive COPD-diseased human bronchial epithelial cells repeatedly exposed to air pollution-derived PM2.5.

  • Human Biomonitoring Research Unit
October 01, 2017
2017 Oct. Environ Pollut.230:163-177. Epub 2017 Jun 23.
By:
  • Leclercq B
  • Platel A
  • Antherieu S
  • Alleman LY
  • Hardy EM
  • Perdrix E
  • Grova N
  • Riffault V
  • Appenzeller BM
  • Happillon M
  • Nesslany F
  • Coddeville P
  • Lo-Guidice JM
  • Garcon G.

Chemical evaluation of electronic cigarettes: Multicomponent analysis of liquid refills and their corresponding aerosols.

  • Human Biomonitoring Research Unit
October 01, 2017
2017 Oct. J Anal Toxicol.41(8):670-678.
By:
  • Beauval N
  • Antherieu S
  • Soyez M
  • Gengler N
  • Grova N
  • Howsam M
  • Hardy EM
  • Fischer M
  • Appenzeller BMR
  • Goossens JF
  • Allorge D
  • Garcon G
  • Lo-Guidice JM
  • Garat A.

New insights into urine-based assessment of polycyclic aromatic hydrocarbon-exposure from a rat model: Identification of relevant metabolites and influence of elimination kinetics.

  • Human Biomonitoring Research Unit
September 01, 2017
2017 Sep. Environ Pollut.228:484-495. Epub 2017 May 30.
By:
  • Grova N
  • Fays F
  • Hardy EM
  • Appenzeller BMR.

Hair analysis for the biomonitoring of pesticide exposure: comparison with blood and urine in a rat model.

  • Human Biomonitoring Research Unit
  • Competence Center for Methodology and Statistics
August 01, 2017
2017 Aug. Arch Toxicol.91(8):2813-2825. Epub 2016 Dec 23.
By:
  • Appenzeller BMR
  • Hardy EM
  • Grova N
  • Chata C
  • Fays F
  • Briand O
  • Schroeder H
  • Duca RC.

Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype.

  • Human Biomonitoring Research Unit
March 15, 2017
2017 Mar. Sci Rep.7(1):195.
By:
  • Hardonniere K
  • Fernier M
  • Gallais I
  • Mograbi B
  • Podechard N
  • Le Ferrec E
  • Grova N
  • Appenzeller B
  • Burel A
  • Chevanne M
  • Sergent O
  • Huc L
  • Bortoli S
  • Lagadic-Gossmann D.

Differential responses of healthy and chronic obstructive pulmonary diseased human bronchial epithelial cells repeatedly exposed to air pollution-derived PM4.

  • Human Biomonitoring Research Unit
November 01, 2016
2016 Nov. Environ Pollut.218:1074-1088. Epub 2016 Sep 1.
By:
  • Leclercq B
  • Happillon M
  • Antherieu S
  • Hardy EM
  • Alleman LY
  • Grova N
  • Perdrix E
  • Appenzeller BM
  • Lo Guidice JM
  • Coddeville P
  • Garcon G.

Epigenetic changes upon multi-residue exposure to polycyclic aromatic hydrocarbons.

  • Human Biomonitoring Research Unit
June 01, 2016
2016 Jun. Proceeding Organohalogen Compounds Database.78:845-847.
By:
  • Duca R
  • Grova N
  • Ghosh M
  • Appenzeller BM
  • Vanoirbeek J
  • Godderis L.

Determination of tetrahydroxylated metabolites in hair and DNA of rats under controlled exposure to a mixture of Polycyclic Aromatic Hydrocarbons: new biomarkers for assessing human exposure.

  • Human Biomonitoring Research Unit
  • Competence Center for Methodology and Statistics
June 01, 2016
2016 Jun. Proceeding Organohalogen Compounds Database.78:445-447.
By:
  • Grova N
  • Hardy EM
  • Fays F
  • Appenzeller BM.