Guy Berchem

Latest publications

CRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis.

  • Cytoskeleton and Cancer Progression
  • NORLUX Neuro-Oncology Laboratory
March 22, 2016
2016 Mar. Oncotarget.7(12):13688-705.
By:
  • Hoffmann C
  • Mao X
  • Dieterle M
  • Moreau F
  • Al Absi A
  • Steinmetz A
  • Oudin A
  • Berchem G
  • Janji B
  • Thomas C.
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Autophagy Activation in the Tumor Microenvironment: A Major Process in Shaping the Antitumor Immune Response. In Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. 1st ed. (Book Chapter)

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
February 25, 2016
2016 Feb. San Diego: Academic Press, 2016. p.267-290. (Vol. 8). ISBN 978-0-12-802937-4.
By:
  • Janji B
  • Viry E
  • Mgrditchian T
  • Arakelian T
  • Medves S
  • Berchem G.
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Assessing cellular and circulating miRNA recovery: the impact of the RNA isolation method and the quantity of input material.

  • Proteomics of Cellular Signaling
  • Platform LUXGEN - Micro-Array
January 20, 2016
2016 Jan. Sci Rep.6:19529.
By:
  • El-Khoury V
  • Pierson S
  • Kaoma T
  • Bernardin F
  • Berchem G.
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

  • Proteomics of Cellular Signaling
  • Tumor Immunotherapy and Microenvironment
January 02, 2016
2016 Jan. Autophagy.12(1):1-222.
By:
  • Klionsky D
  • Abdelmohsenn K
  • Abe A
  • Abedin M
  • et al (incl. El-Khoury V Janji B and Berchem G).
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Autophagy regulation of the tumor immunity: An old housekeeper for a new function. In Cell Death - Autophagy, Necrosis and Apoptosis. (Book Chapter)

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
December 16, 2015
2015 Dec. Ntuli DT, ed. Rijeka: InTech, 2015. p.37-61. ISBN 978-953-51-2236-4.
By:
  • Arakelian T
  • Mgrditchian T
  • Viry E
  • Van Moer K
  • Berchem G
  • Chouaib S
  • Janji B.
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Quantification of SAA1 and SAA2 in Lung Cancer Plasma Using the Isotype-specific PRM Assays.

  • Proteomics of Cellular Signaling
September 01, 2015
2015 Sep. Proteomics.15(18):3116-25. Epub 2015 Aug 17.
By:
  • Kim YJ
  • Gallien S
  • El-Khoury V
  • Goswami P
  • Sertamo K
  • Schlesser M
  • Berchem G
  • Domon B.
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Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts.

  • Tumor Stroma Interactions
  • Tumor Immunotherapy and Microenvironment
  • Integrated BioBank of Luxembourg
  • Proteomics of Cellular Signaling
August 27, 2015
2015 Aug. Blood.126(9):1106-17. Epub 2015 Jun 22.
By:
  • Paggetti J
  • Haderk F
  • Seiffert M
  • Janji B
  • Distler U
  • Ammerlaan W
  • Kim YJ
  • Adam J
  • Lichter P
  • Solary E
  • Berchem G
  • Moussay E.
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Screening protein isoforms predictive for cancer using immunoaffinity capture and fast LC-MS in PRM mode.

  • Proteomics of Cellular Signaling
  • Tumor Immunotherapy and Microenvironment
August 01, 2015
2015 Aug. Proteomics Clin Appl.9(7-8):695-705. Epub 2015 Mar 30.
By:
  • Lesur A
  • Ancheva L
  • Kim YJ
  • Berchem G
  • van Oostrum J
  • Domon B.
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Epigenetic activity of peroxisome proliferator-activated receptor gamma agonists increases the anticancer effect of histone deacetylase inhibitors on multiple myeloma cells.

  • Tumor Immunotherapy and Microenvironment
  • Translational Radiomics
  • Laboratory of Oncolytic-Virus-Immuno-Therapeutics
June 19, 2015
2015 Jun. PLoS One.10(6):e0130339.
By:
  • Aouali N
  • Broukou A
  • Bosseler M
  • Keunen O
  • Schlesser V
  • Janji B
  • Palissot V
  • Stordeur P
  • Berchem G.
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Verification of the biomarker candidates for non-small-cell lung cancer using a targeted proteomics approach.

  • Proteomics of Cellular Signaling
  • Tumor Stroma Interactions
March 06, 2015
2015 Mar. J Proteome Res.14(3):1412-9. Epub 2015 Feb 9.
By:
  • Kim YJ
  • Sertamo K
  • Pierrard MA
  • Mesmin C
  • Kim SY
  • Schlesser M
  • Berchem G
  • Domon B.
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First-line crizotinib versus chemotherapy in ALK-positive lung cancer.

  • Tumor Immunotherapy and Microenvironment
December 04, 2014
2014 Dec. N Engl J Med.371(23):2167-77.
By:
  • Solomon BJ
  • Mok T
  • Kim DW
  • Wu YL
  • Nakagawa K
  • Mekhail T
  • Felip E
  • Cappuzzo F
  • Paolini J
  • Usari T
  • Iyer S
  • Reisman A
  • Wilner KD
  • Tursi J
  • Blackhall F
  • PROFILE 1014 Investigators (Berchem G as collaborator for this project).
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Hypoxia: A key feature of the tumor microenvironment triggers several mechanisms of evasion from natural killer and cytotoxic T lymphocytes surveillance.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
  • Cytoskeleton and Cancer Progression
November 20, 2014
2014 Nov. J Imm Res.1(2):7.
By:
  • Mgrditchian T
  • Arakelian T
  • Paggetti J
  • Viry E
  • Al-Absi A
  • Medves S
  • Moussay E
  • Berchem G
  • Thomas C
  • Janji B.
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Autophagy: An adaptive metabolic response to stress shaping the antitumor immunity.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
November 01, 2014
2014 Nov. Biochem Pharmacol.92(1):31-42. Epub 2014 Jul 17.
By:
  • Viry E
  • Paggetti J
  • Baginska J
  • Mgrditchian T
  • Berchem G
  • Moussay E
  • Janji B.
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Two biomarker-directed randomized trials in European and Chinese patients with nonsmall-cell lung cancer: the BRCA1-RAP80 Expression Customization (BREC) studies.

  • Tumor Immunotherapy and Microenvironment
November 01, 2014
2014 Nov. Ann Oncol.25(11):2147-55. Epub 2014 Aug 27.
By:
  • Moran T
  • Wei J
  • Cobo M
  • Qian X
  • Domine M
  • Zou Z
  • Bover I
  • Wang L
  • Provencio M
  • Yu L
  • Chaib I
  • You C
  • Massuti B
  • Song Y
  • Vergnenegre A
  • Lu H
  • Lopez-Vivanco G
  • Hu W
  • Robinet G
  • Yan J
  • Insa A
  • Xu X
  • Majem M
  • Chen X
  • de Las Penas R
  • Karachaliou N
  • Sala MA
  • Wu Q
  • Isla D
  • Zhou Y
  • Baize N
  • Zhang F
  • Garde J
  • Germonpre P
  • Rauh S
  • H AL
  • Sanchez-Ronco M
  • Drozdowskyj A
  • Sanchez JJ
  • Camps C
  • Liu B
  • Rosell R
  • Spanish Lung Cancer Group
  • French Lung Cancer Group
  • Comprehensive Cancer Centre of Drum Tower Hospital in Nanjing
  • Berchem G (as collaborator for investigators participating in the BREC trials).
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Hypoxia-induced autophagy in tumor cells: a key target for improving cancer immunotherapy.

  • Tumor Stroma Interactions
  • Tumor Immunotherapy and Microenvironment
September 14, 2014
2014 Sep. Cancer Cell Microenviron.1(4):e213.
By:
  • Paggetti J
  • Viry E
  • Berchem G
  • Moussay E
  • Janji B.
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[Editorial].

  • Tumor Immunotherapy and Microenvironment
August 01, 2014
2014 Aug. Bull Soc Sci Med Grand Duche Luxemb.(2):7-8.
By:
  • Berchem G.
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Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia.

  • Tumor Stroma Interactions
  • Platform National Cytometry
  • NORLUX Neuro-Oncology Laboratory
August 01, 2014
2014 Aug. Leukemia.28(8):1636-46. Epub 2014 Jan 14.
By:
  • El-Khoury V
  • Pierson S
  • Szwarcbart E
  • Brons NH
  • Roland O
  • Cherrier-De Wilde S
  • Plawny L
  • Van Dyck E
  • Berchem G.
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BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization.

  • Tumor Immunotherapy and Microenvironment
July 01, 2014
2014 Jul. Autophagy.10(7):1341-1342. Epub 2014 May 15.
By:
  • Sebti S
  • Prebois C
  • Perez-Gracia E
  • Bauvy C
  • Desmots F
  • Pirot N
  • Gongora C
  • Bach AS
  • Hubberstey AV
  • Palissot V
  • Berchem G
  • Codogno P
  • Linares LK
  • Liaudet-Coopman E
  • Pattingre S.
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Bronchial airway gene expression in smokers with lung or head and neck cancer.

  • NORLUX Neuro-Oncology Laboratory
  • Platform LUXGEN - Micro-Array
  • Tumor Immunotherapy and Microenvironment
April 01, 2014
2014 Apr. Cancer Med.3(2):322-36. Epub 2014 Feb 4.
By:
  • Van Dyck E
  • Nazarov PV
  • Muller A
  • Nicot N
  • Bosseler M
  • Pierson S
  • Van Moer K
  • Palissot V
  • Mascaux C
  • Knolle U
  • Ninane V
  • Nati R
  • Bremnes RM
  • Vallar L
  • Berchem G
  • Schlesser M.
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BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy.

  • Tumor Immunotherapy and Microenvironment
March 18, 2014
2014 Mar. Proc Natl Acad Sci U S A.111(11):4115-20. Epub 2014 Mar 3.
By:
  • Sebti S
  • Prebois C
  • Perez-Gracia E
  • Bauvy C
  • Desmots F
  • Pirot N
  • Gongora C
  • Bach AS
  • Hubberstey AV
  • Palissot V
  • Berchem G
  • Codogno P
  • Linares LK
  • Liaudet-Coopman E
  • Pattingre S.
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