Bassam Janji

Latest publications

The critical role of the tumor microenvironment in shaping natural killer cell-mediated anti-tumor immunity.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
December 01, 2013
2013 Dec. Front Immunol.4:490.
By:
  • Baginska J
  • Viry E
  • Paggetti J
  • Medves S
  • Berchem G
  • Moussay E
  • Janji B.
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Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia.

  • Tumor Immunotherapy and Microenvironment
  • NORLUX Neuro-Oncology Laboratory
October 22, 2013
2013 Oct. Proc Natl Acad Sci U S A.110(43):17450-5. Epub 2013 Oct 7.
By:
  • Baginska J
  • Viry E
  • Berchem G
  • Poli A
  • Noman MZ
  • van Moer K
  • Medves S
  • Zimmer J
  • Oudin A
  • Niclou SP
  • Bleackley RC
  • Goping IS
  • Chouaib S
  • Janji B.
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EMT impairs breast carcinoma cell susceptibility to CTL-mediated lysis through autophagy induction.

  • Tumor Immunotherapy and Microenvironment
July 01, 2013
2013 Jul. Autophagy.9(7):1104-6. Epub 2013 Apr 23.
By:
  • Akalay I
  • Janji B
  • Hasmim M
  • Noman MZ
  • Thiery JP
  • Mami-Chouaib F
  • Chouaib S.
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Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell-mediated lysis.

  • Tumor Immunotherapy and Microenvironment
April 15, 2013
2013 Apr. Cancer Res.73(8):2418-27. Epub 2013 Feb 22.
By:
  • Akalay I
  • Janji B
  • Hasmim M
  • Noman MZ
  • Andre F
  • De Cremoux P
  • Bertheau P
  • Badoual C
  • Vielh P
  • Larsen AK
  • Sabbah M
  • Tan TZ
  • Keira JH
  • Hung NT
  • Thiery JP
  • Mami-Chouaib F
  • Chouaib S.
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Hypoxia-inducible miR-210 regulates the susceptibility of tumor cells to lysis by cytotoxic T cells.

  • Tumor Immunotherapy and Microenvironment
September 15, 2012
2012 Sep. Cancer Res.72(18):4629-41. Epub 2012 Sep 7.
By:
  • Noman MZ
  • Buart S
  • Romero P
  • Ketari S
  • Janji B
  • Mari B
  • Mami-Chouaib F
  • Chouaib S.
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Guidelines for the use and interpretation of assays for monitoring autophagy.

  • Tumor Immunotherapy and Microenvironment
April 01, 2012
2012 Apr. Autophagy.8(4):445-544.
By:
  • Klionsky DJ
  • Abdalla FC
  • et al (incl. Janji B).
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Hypoxia-induced autophagy: a new player in cancer immunotherapy?

  • Tumor Immunotherapy and Microenvironment
April 01, 2012
2012 Apr. Autophagy.8(4):704-6. Epub 2012 Apr 1.
By:
  • Noman MZ
  • Janji B
  • Berchem G
  • Mami-Chouaib F
  • Chouaib S.
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Role of the actin cytoskeleton in tumor escape to immune system and acquisition of tumor resistance to cytotoxic treatment. In Actin: Structure, functions and disease. (Book Chapter)

  • Tumor Immunotherapy and Microenvironment
January 01, 2012
2012 Jan. Consuelas VA and Minas DJ, eds. Hauppauge, New York: Nova Science Publishers, 2012. p.245-255. (Protein Biochemistry, Synthesis, Structure and Cellular Functions). ISBN 978-1-62100-191-1.
By:
  • Zaarour R
  • Goh F
  • Hasmim M
  • Janji B
  • Chouaib S.
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Microenvironmental hypoxia orchestrating the cell stroma cross talk, tumor progression and antitumor response.

  • Tumor Immunotherapy and Microenvironment
December 01, 2011
2011 Dec. Crit Rev Immunol.31(5):357-77.
By:
  • Noman MZ
  • Messai Y
  • Carre T
  • Akalay I
  • Meron M
  • Janji B
  • Hasmim M
  • Chouaib S.
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Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
September 15, 2011
2011 Sep. Cancer Res.71(18):5976-86. Epub 2011 Aug 2.
By:
  • Noman MZ
  • Janji B
  • Kaminska B
  • Van Moer K
  • Pierson S
  • Przanowski P
  • Buart S
  • Berchem G
  • Romero P
  • Mami-Chouaib F
  • Chouaib S.
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The acquisition of resistance to TNFalpha in breast cancer cells is associated with constitutive activation of autophagy as revealed by a transcriptome analysis using a custom microarray.

  • Tumor Stroma Interactions
  • Tumor Immunotherapy and Microenvironment
  • Platform LUXGEN - Micro-Array
July 01, 2011
2011 Jul. Autophagy.7(7):760-70. Epub 2011 Jul 1.
By:
  • Moussay E
  • Kaoma T
  • Baginska J
  • Muller A
  • Van Moer K
  • Nicot N
  • Nazarov PV
  • Vallar L
  • Chouaib S
  • Berchem G
  • Janji B.
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The actin filament cross-linker L-plastin confers resistance to TNF-alpha in MCF-7 breast cancer cells in a phosphorylation-dependent manner.

  • Tumor Immunotherapy and Microenvironment
  • Platform LUXGEN - Micro-Array
June 01, 2010
2010 Jun. J Cell Mol Med.14(6A):1264-75. Epub 2009 Oct 3.
By:
  • Janji B
  • Vallar L
  • Al Tanoury Z
  • Bernardin F
  • Vetter G
  • Schaffner-Reckinger E
  • Berchem G
  • Friederich E
  • Chouaib S.
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The histone deacetylase inhibitor MGCD0103 induces apoptosis in B-cell chronic lymphocytic leukemia cells through a mitochondria-mediated caspase activation cascade.

  • Tumor Stroma Interactions
  • Tumor Immunotherapy and Microenvironment
  • Platform National Cytometry
April 20, 2010
2010 Apr. Mol Cancer Ther.9(5):1349-60. Epub 2010 Apr 20.
By:
  • El-Khoury V
  • Moussay E
  • Janji B
  • Palissot V
  • Aouali N
  • Brons NH
  • Van Moer K
  • Pierson S
  • Van Dyck E
  • Berchem G.
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Immune surveillance of human cancer: if the cytotoxic T-lymphocytes play the music, does the tumoral system call the tune?

  • Tumor Immunotherapy and Microenvironment
January 01, 2010
2010 Jan. Tissue Antigens.75(1):1-8.
By:
  • Hamai A
  • Benlalam H
  • Meslin F
  • Hasmim M
  • Carre T
  • Akalay I
  • Janji B
  • Berchem G
  • Noman MZ
  • Chouaib S.
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