Bassam Janji

Latest publications

CRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis.

  • Cytoskeleton and Cancer Progression
  • NORLUX Neuro-Oncology Laboratory
March 22, 2016
2016 Mar. Oncotarget.7(12):13688-705.
By:
  • Hoffmann C
  • Mao X
  • Dieterle M
  • Moreau F
  • Al Absi A
  • Steinmetz A
  • Oudin A
  • Berchem G
  • Janji B
  • Thomas C.

Autophagy Activation in the Tumor Microenvironment: A Major Process in Shaping the Antitumor Immune Response. In Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. 1st ed. (Book Chapter)

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
February 25, 2016
2016 Feb. San Diego: Academic Press, 2016. p.267-290. (Vol. 8). ISBN 978-0-12-802937-4.
By:
  • Janji B
  • Viry E
  • Mgrditchian T
  • Arakelian T
  • Medves S
  • Berchem G.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

  • Proteomics of Cellular Signaling
  • Tumor Immunotherapy and Microenvironment
January 02, 2016
2016 Jan. Autophagy.12(1):1-222.
By:
  • Klionsky D
  • Abdelmohsenn K
  • Abe A
  • Abedin M
  • et al (incl. El-Khoury V Janji B and Berchem G).

Autophagy regulation of the tumor immunity: An old housekeeper for a new function. In Cell Death - Autophagy, Necrosis and Apoptosis. (Book Chapter)

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
December 16, 2015
2015 Dec. Ntuli DT, ed. Rijeka: InTech, 2015. p.37-61. ISBN 978-953-51-2236-4.
By:
  • Arakelian T
  • Mgrditchian T
  • Viry E
  • Van Moer K
  • Berchem G
  • Chouaib S
  • Janji B.

Hypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to Hypoxia.

  • Tumor Immunotherapy and Microenvironment
November 01, 2015
2015 Nov. Am J Physiol Cell Physiol.309(9):C569-79. Epub 2015 Aug 26.
By:
  • Noman MZ
  • Hasmim M
  • Messai Y
  • Terry S
  • Kieda C
  • Janji B
  • Chouaib S.

miR-181a modulates acute myeloid leukemia susceptibility to natural killer cells.

  • Tumor Immunotherapy and Microenvironment
October 16, 2015
2015 Oct. OncoImmunology.4(12):e996475.
By:
  • Nanbakhsh A
  • Visentin G
  • Olive D
  • Janji B
  • Mussard E
  • Dessen P
  • Meurice G
  • Zhang Y
  • Louache F
  • Bourhis JH
  • Chouaib S.

The selective degradation of synaptic connexin 43 protein by hypoxia-induced autophagy impairs natural killer cell-mediated tumor cell killing.

  • Tumor Immunotherapy and Microenvironment
September 25, 2015
2015 Sep. J Biol Chem.290(39):23670-9. Epub 2015 Jul 28.
By:
  • Tittarelli A
  • Janji B
  • Van Moer K
  • Noman MZ
  • Chouaib S.

Tumor-promoting effects of myeloid derived suppressor cells are potentiated by hypoxia-induced expression of miR-210.

  • Tumor Immunotherapy and Microenvironment
September 15, 2015
2015 Sep. Cancer Res.75(18):3771-87. Epub 2015 Jul 23.
By:
  • Noman MZ
  • Janji B
  • Hu S
  • Wu JC
  • Martelli F
  • Bronte V
  • Chouaib S.

Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts.

  • Tumor Stroma Interactions
  • Tumor Immunotherapy and Microenvironment
  • Integrated BioBank of Luxembourg
  • Proteomics of Cellular Signaling
August 27, 2015
2015 Aug. Blood.126(9):1106-17. Epub 2015 Jun 22.
By:
  • Paggetti J
  • Haderk F
  • Seiffert M
  • Janji B
  • Distler U
  • Ammerlaan W
  • Kim YJ
  • Adam J
  • Lichter P
  • Solary E
  • Berchem G
  • Moussay E.

Hypoxia: A Formidable Saboteur of the Anti-tumor Response. In Resistance of Cancer Cells to CTL-Mediated Immunotherapy. (Book Chapter)

  • Tumor Immunotherapy and Microenvironment
June 20, 2015
2015 Jun. Bonavida B and Chouaib S, eds. Springer, 2015. p.115-142. (Series Resistance to Targeted Anti-Cancer Therapeutics, Vol. 7). ISBN 978-3-319-17806-6.
By:
  • Hasmim M
  • Messai Y
  • Terry S
  • Janji B
  • Noman M
  • Chouaib S.

Epigenetic activity of peroxisome proliferator-activated receptor gamma agonists increases the anticancer effect of histone deacetylase inhibitors on multiple myeloma cells.

  • Tumor Immunotherapy and Microenvironment
  • Translational Radiomics
  • Laboratory of Oncolytic-Virus-Immuno-Therapeutics
June 19, 2015
2015 Jun. PLoS One.10(6):e0130339.
By:
  • Aouali N
  • Broukou A
  • Bosseler M
  • Keunen O
  • Schlesser V
  • Janji B
  • Palissot V
  • Stordeur P
  • Berchem G.

Targeting WNT1-inducible signaling pathway protein 2 alters human breast cancer cell susceptibility to specific lysis through regulation of KLF-4 and miR-7 expression.

  • Tumor Immunotherapy and Microenvironment
April 23, 2015
2015 Apr. Oncogene.34(17):2261-71. Epub 2014 Jun 16.
By:
  • Akalay I
  • Tan TZ
  • Kumar P
  • Janji B
  • Mami-Chouaib F
  • Charpy C
  • Vielh P
  • Larsen AK
  • Thiery JP
  • Sabbah M
  • Chouaib S.

The autophagy sensor ITPR1 protects renal carcinoma cells from NK-mediated killing.

  • Tumor Immunotherapy and Microenvironment
February 25, 2015
2015 Feb. Autophagy. [Epub ahead of print].
By:
  • Messai Y
  • Noman MZ
  • Janji B
  • Hasmim M
  • Escudier B
  • Chouaib S.

ITPR1 protects renal cancer cells against natural killer cells by inducing autophagy.

  • Tumor Immunotherapy and Microenvironment
December 01, 2014
2014 Dec. Cancer Res.74(23):6820-32. Epub 2014 Oct 8.
By:
  • Messai Y
  • Noman MZ
  • Hasmim M
  • Janji B
  • Tittarelli A
  • Boutet M
  • Baud V
  • Viry E
  • Billot K
  • Nanbakhsh A
  • Ben Safta T
  • Richon C
  • Ferlicot S
  • Donnadieu E
  • Couve S
  • Gardie B
  • Orlanducci F
  • Albiges L
  • Thiery J
  • Olive D
  • Escudier B
  • Chouaib S.

Hypoxia: A key feature of the tumor microenvironment triggers several mechanisms of evasion from natural killer and cytotoxic T lymphocytes surveillance.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
  • Cytoskeleton and Cancer Progression
November 20, 2014
2014 Nov. J Imm Res.1(2):7.
By:
  • Mgrditchian T
  • Arakelian T
  • Paggetti J
  • Viry E
  • Al-Absi A
  • Medves S
  • Moussay E
  • Berchem G
  • Thomas C
  • Janji B.

Autophagy: An adaptive metabolic response to stress shaping the antitumor immunity.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
November 01, 2014
2014 Nov. Biochem Pharmacol.92(1):31-42. Epub 2014 Jul 17.
By:
  • Viry E
  • Paggetti J
  • Baginska J
  • Mgrditchian T
  • Berchem G
  • Moussay E
  • Janji B.

Hypoxia-induced autophagy in tumor cells: a key target for improving cancer immunotherapy.

  • Tumor Stroma Interactions
  • Tumor Immunotherapy and Microenvironment
September 14, 2014
2014 Sep. Cancer Cell Microenviron.1(4):e213.
By:
  • Paggetti J
  • Viry E
  • Berchem G
  • Moussay E
  • Janji B.

Tumor plasticity interferes with anti-tumor immunity.

  • Tumor Immunotherapy and Microenvironment
June 19, 2014
2014 Jun. Crit Rev Immunol.34(2):91-102.
By:
  • Chouaib S
  • Janji B
  • Tittarelli A
  • Eggermont A
  • Thiery JP.

PD-L1 is a novel direct target of HIF-1alpha, and its blockade under hypoxia enhanced MDSC-mediated T cell activation.

  • Tumor Immunotherapy and Microenvironment
May 05, 2014
2014 May. J Exp Med.211(5):781-90. Epub 2014 Apr 28.
By:
  • Noman MZ
  • Desantis G
  • Janji B
  • Hasmim M
  • Karray S
  • Dessen P
  • Bronte V
  • Chouaib S.

Autophagic degradation of GZMB/granzyme B: a new mechanism of hypoxic tumor cell escape from natural killer cell-mediated lysis.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
January 01, 2014
2014 Jan. Autophagy.10(1):173-5. Epub 2013 Nov 15.
By:
  • Viry E
  • Baginska J
  • Berchem G
  • Noman MZ
  • Medves S
  • Chouaib S
  • Janji B.