Andy Chevigne
Latest publications
Systematic reassessment of chemokine-receptor pairings confirms CCL20 but not CXCL13 and extends the spectrum of ACKR4 agonists to CCL22.
- Immuno-Pharmacology and Interactomics
2021 Feb. J Leukoc Biol.109(2):373-376. Epub 2020 Jun 1.
CXCR4-binding Positron Emission Tomography tracers link monocyte recruitment and endothelial injury in murine atherosclerosis.
- Immuno-Pharmacology and Interactomics
2020 Dec. Arterioscler Thromb Vasc Biol.ATVBAHA120315053. Online ahead of print.
CXCL14 Preferentially Synergizes With Homeostatic Chemokine Receptor Systems.
- Immuno-Pharmacology and Interactomics
2020 Oct. Front Immunol.11:561404.
GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11.
- Immuno-Pharmacology and Interactomics
2020 Sep. Nat Commun.11(1):4752.
The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides.
- Immuno-Pharmacology and Interactomics
- Immune Endocrine and Epigenetics
- Transversal Translational Medicine
- Allergy and Clinical Immunology
2020 Jun. Nat Commun.11(1):3033.
Assessment of biased agonism among distinct synthetic cannabinoid receptor agonist scaffolds.
- Immuno-Pharmacology and Interactomics
2020 Apr. ACS Pharmacol Transl Sci.3(2):285-295.
Structural features of an extended C-terminal tail modulate function of the chemokine CCL21.
- Immuno-Pharmacology and Interactomics
2020 Apr. Biochemistry.59(13):1338-1350. Epub 2020 Mar 26.
The diverse and complex roles of atypical chemokine receptors in cancer: From molecular biology to clinical relevance and therapy.
- Immuno-Pharmacology and Interactomics
2020 Feb. Adv Cancer Res.145:99-138. Epub 2020 Feb 14.
The soluble form of pan-RTK inhibitor and tumor suppressor LRIG1 mediates downregulation of AXL through direct protein-protein interaction in glioblastoma.
- NORLUX Neuro-Oncology Laboratory
- Multiomics Data Science
- Immuno-Pharmacology and Interactomics
2019 Sep. Neurooncol Adv.1(1):vdz024.
Predominance of the heterozygous CCR5 delta-24 deletion in African individuals resistant to HIV infection might be related to a defect in CCR5 addressing at the cell surface.
- HIV Clinical and Translational Research
- Platform National Cytometry
- Immuno-Pharmacology and Interactomics
2019 Sep. J Int AIDS Soc.22(9):e25384.
The distinct roles of CXCR3 variants and their ligands in the tumor microenvironment.
- Immuno-Pharmacology and Interactomics
- Tumor Immunotherapy and Microenvironment
- NORLUX Neuro-Oncology Laboratory
2019 Jun. Cells.8(6).
A novel ACKR2-dependent role of fibroblast-derived CXCL14 in epithelial-to-mesenchymal transition and metastasis of breast cancer.
- Immuno-Pharmacology and Interactomics
2019 Jun. Clin Cancer Res.25(12):3702-3717. Epub 2019 Mar 8.
Aurora A plays a dual role in migration and survival of human glioblastoma cells according to the CXCL12 concentration.
- Immuno-Pharmacology and Interactomics
2019 Jan. Oncogene.38(1):73-87. Epub 2018 Aug 6.
Driving cytotoxic natural killer cells into melanoma: If CCL5 plays the music, autophagy calls the shots.
- Tumor Immunotherapy and Microenvironment
- Immuno-Pharmacology and Interactomics
- Allergy and Clinical Immunology
2018 Sep. Crit Rev Oncog.23(5-6):321-332.
Development of Mimokines, chemokine N terminus-based CXCR4 inhibitors optimized by phage display and rational design.
- Immuno-Pharmacology and Interactomics
- HIV Clinical and Translational Research
2018 Aug. J Leukoc Biol.104(2):343-357. Epub 2018 Mar 23.
Emerging roles of the protease allergen Der p 1 in house dust mite-induced airway inflammation.
- Immuno-Pharmacology and Interactomics
2018 Aug. J Allergy Clin Immunol.142(2):398-400. Epub 2018 Jun 12.
Mutational analysis of the extracellular disulphide bridges of the atypical chemokine receptor ACKR3/CXCR7 uncovers multiple binding and activation modes for its chemokine and endogenous non-chemokine agonists.
- Immuno-Pharmacology and Interactomics
2018 Jul. Biochem Pharmacol.153:299-309. Epub 2018 Mar 9.
Different contributions of chemokine N-terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3.
- Immuno-Pharmacology and Interactomics
2018 May. Br J Pharmacol.175(9):1419-1438. Epub 2018 Mar 23.
Profiling the extended cleavage specificity of the house dust mite protease allergens Der p 1, Der p 3 and Der p 6 for the prediction of new cell surface protein substrates.
- Immuno-Pharmacology and Interactomics
2017 Jun. Int J Mol Sci.18(7).
Activation of the orphan G protein-coupled receptor GPR27 by surrogate ligands promotes beta-arrestin 2 recruitment.
- Immuno-Pharmacology and Interactomics
2017 Jun. Mol Pharmacol.91(6):595-608. Epub 2017 Mar 17.