Alessandro Michelucci
Latest publications
NF-κB and TNF Affect the Astrocytic Differentiation from Neural Stem Cells.
- Neuro-Immunology Group
2021 Apr. Cells.10(4):840.
Microglia in health and disease: The strength to be diverse and reactive.
- Neuro-Immunology Group
- Luxembourg Center of Neuropathology
2021 Mar. Front Cell Neurosci.
Single-cell transcriptomics and in situ morphological analyses reveal microglia heterogeneity across the nigrostriatal pathway.
- Neuro-Immunology Group
- Luxembourg Center of Neuropathology
2021 Mar. Front Immunol.12:639613. Accepted.
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.
- NORLUX Neuro-Oncology Laboratory
- Translational Radiomics
- Neuro-Immunology Group
- Computational Biomedicine
- Multiomics Data Science
- Luxembourg Center of Neuropathology
- Personalized Therapy Discovery
2020 Dec. Acta Neuropathol.140(6):919-949. Epub 2020 Oct 3.
Pituitary tumor transforming gene 1 orchestrates gene regulatory variation in mouse ventral midbrain during aging.
- Neuro-Immunology Group
- Luxembourg Center of Neuropathology
2020 Sep. Front Genet.11(1119).
Revealing and harnessing tumour-associated microglia/macrophage heterogeneity in glioblastoma.
- Neuro-Immunology Group
- NORLUX Neuro-Oncology Laboratory
2020 Jan. Int J Mol Sci.21(3):E689.
Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment.
- NORLUX Neuro-Oncology Laboratory
- Computational Biomedicine
- Competence Center for Methodology and Statistics
- Platform National Cytometry
2019 Apr. Nat Commun.10(1):1787.
Transcriptional and epigenetic mechanisms underlying astrocyte identity.
- NORLUX Neuro-Oncology Laboratory
2019 Mar. Prog Neurobiol.174:36-52. Epub 2018 Dec 29.
The itaconate pathway is a central regulatory node linking innate immune tolerance and trained immunity.
- NORLUX Neuro-Oncology Laboratory
2019 Jan. Cell Metab.29(1):211-220 e5. Epub 2018 Oct 4.
Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures.
- NORLUX Neuro-Oncology Laboratory
- Computational Biomedicine
2018 Nov. EMBO Rep.19(11). Epub 2018 Sep 11.
Microglia in health and disease: A unique immune cell population. (Book)
- NORLUX Neuro-Oncology Laboratory
- Luxembourg Center of Neuropathology
2018 Sep. Michelucci A, Mittelbronn M and Gomez-Nicola D, eds. Lausanne: Frontiers Media, 2018. 106 p. (Frontiers Research topic). ISBN 978-2-88945-601-7.
Microglia in health and disease: a unique immune cell population.
- NORLUX Neuro-Oncology Laboratory
- Luxembourg Center of Neuropathology
2018 Aug. Front Immunol.9:1779.
Integrative computational network analysis reveals site-specific mediators of inflammation in Alzheimer's disease.
- NORLUX Neuro-Oncology Laboratory
2018 Mar. Front Physiol.9:154.
Cellular and molecular characterization of microglia: A unique immune cell population.
- NORLUX Neuro-Oncology Laboratory
2017 Mar. Front Immunol.8:198.
Inflammation promotes a conversion of astrocytes into neural progenitor cells via NF-kappaB activation.
- NORLUX Neuro-Oncology Laboratory
2016 Oct. Mol Neurobiol.53(8):5041-55. Epub 2015 Sep 17.
The Neurogenic Potential of Astrocytes Is Regulated by Inflammatory Signals.
- NORLUX Neuro-Oncology Laboratory
2016 Aug. Mol Neurobiol.53(6):3724-3739. Epub 2015 Jul 4.
Immunoresponsive gene 1 and itaconate inhibit succinate dehydrogenase to modulate intracellular succinate levels.
- NORLUX Neuro-Oncology Laboratory
2016 Jul. J Biol Chem.291(27):14274-84. Epub 2016 May 9.
Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism.
- NORLUX Neuro-Oncology Laboratory
2016 May. Neurobiol Dis.89:112-25. Epub 2016 Feb 1.
Transcriptomic analyses of primary astrocytes under TNFα treatment.
- NORLUX Neuro-Oncology Laboratory
2016 Mar. Genom Data.7:7-11.
Gene regulatory network inference of Immunoresponsive Gene 1 (IRG1) identifies Interferon Regulatory Factor 1 (IRF1) as its transcriptional regulator in mammalian macrophages.
- NORLUX Neuro-Oncology Laboratory
- Platform LUXGEN - Micro-Array
2016 Feb. PLoS One.11(2):e0149050.