Molecular allergology and its impact in specific allergy diagnosis and therapy.

  • Department of Infection and Immunity
May 31, 2021 By:
  • Barber D
  • Diaz-Perales A
  • Escribese MM
  • Kleine-Tebbe J
  • Matricardi P
  • Ollert M
  • Santos AF
  • Sastre J.

Progressive knowledge of allergenic structures resulted in a broad availability of allergenic molecules for diagnosis. Component resolved diagnosis allowed a better understanding of patient sensitization patterns, facilitating allergen immunotherapy decisions. In parallel to the discovery of allergenic molecules, there was a progressive development of a regulation framework that affected both in vitro diagnostics and Allergen Immunotherapy products. With a progressive understanding of underlying mechanisms associated to Allergen immunotherapy and an increasing experience of application of molecular diagnosis in daily life, we focus in analyzing the evidencesof the value provided by molecular allergology in daily clinical practice, with a focus on Allergen Immunotherapy decisions.

2021 May. Allergy. Online ahead of print.
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