Marker allergens in Hymenoptera venom allergy — Characteristics and potential use in precision medicine.

  • Allergy and Clinical Immunology
November 17, 2020 By:
  • Blank S
  • Bilò MB
  • Grosch J
  • Schmidt-Weber CB
  • Ollert M
  • Jakob T.

A comprehensive diagnostic work-up is essential to ensure adequate patient management for the potentially life-threatening condition of Hymenoptera venom allergy (HVA). This includes an unambiguous identification of the allergy-relevant venom as prerequisite for successful venom-specific immunotherapy (VIT). If the clinical history does not allow the identification of the culprit insect, diagnosis is often hampered by positive test results to various venoms. Modern component-resolved diagnostics (CRD) applying marker allergens of Hymenoptera venoms has created new opportunities which facilitate therapeutic decisions and may allow personalized risk stratification for individual patients.

2020 Nov. Allergo J Int.
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